Madeleine M. Joullié
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Madeleine M. Joullié
Madeleine M. Joullié (born March 29, 1927) is a French-born American organic chemist. She was the first woman to join the University of Pennsylvania chemistry faculty as well as the first female organic chemist to be appointed to a tenure track position in a major American university. She was one of the first affirmative action officers at the University of Pennsylvania. She has a distinguished record as a teacher of both undergraduate and graduate-level organic chemistry, and as a mentor of students. Joullié is also an active researcher in organic chemistry who has published three textbooks of organic chemistry, more than 18 review articles, and more than 300 scientific papers. Her work in synthesizing organic compounds such as tilorone, furanomycin, and numerous cyclopeptides has led to the development of antibiotic and antiviral drugs. Joullié has received numerous awards, including the 1978 Garvan Medal from the American Chemical Society, in recognition of her accompl ...
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Paris
Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. Since the 17th century, Paris has been one of the world's major centres of finance, diplomacy, commerce, fashion, gastronomy, and science. For its leading role in the arts and sciences, as well as its very early system of street lighting, in the 19th century it became known as "the City of Light". Like London, prior to the Second World War, it was also sometimes called the capital of the world. The City of Paris is the centre of the Île-de-France region, or Paris Region, with an estimated population of 12,262,544 in 2019, or about 19% of the population of France, making the region France's primate city. The Paris Region had a GDP of €739 billion ($743 billion) in 2019, which is the highest in Europe. According to the Economist Intelli ...
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São Paulo
São Paulo (, ; Portuguese for 'Saint Paul') is the most populous city in Brazil, and is the capital of the state of São Paulo, the most populous and wealthiest Brazilian state, located in the country's Southeast Region. Listed by the GaWC as an alpha global city, São Paulo is the most populous city proper in the Americas, the Western Hemisphere and the Southern Hemisphere, as well as the world's 4th largest city proper by population. Additionally, São Paulo is the largest Portuguese-speaking city in the world. It exerts strong international influences in commerce, finance, arts and entertainment. The city's name honors the Apostle, Saint Paul of Tarsus. The city's metropolitan area, the Greater São Paulo, ranks as the most populous in Brazil and the 12th most populous on Earth. The process of conurbation between the metropolitan areas around the Greater São Paulo (Campinas, Santos, Jundiaí, Sorocaba and São José dos Campos) created the São Paulo Macrometr ...
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Ugi Reaction
The Ugi reaction is a multi-component reaction in organic chemistry involving a ketone or aldehyde, an amine, an isocyanide and a carboxylic acid to form a bis-amide. The reaction is named after Ivar Karl Ugi, who first reported this reaction in 1959. The Ugi reaction is exothermic and usually complete within minutes of adding the isocyanide. High concentration (0.5M - 2.0M) of reactants give the highest yields. Polar, aprotic solvents, like DMF, work well. However, methanol and ethanol have also been used successfully. This uncatalyzed reaction has an inherent high atom economy as only a molecule of water is lost, and the chemical yield in general is high. Several reviews have been published. Due to the reaction products being potential protein mimetics there have been many attempts to development an enantioselective Ugi reaction, the first successful report of which was in 2018. Reaction mechanism One plausible reaction mechanism is depicted below: Amine 1 and ketone ...
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Furanomycin
Furanomycin is an isoleucine Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form under biological conditions), an α-carboxylic acid group (which is in the deprot ... antagonist. References {{heterocyclic-stub Amino acids Dihydrofurans ...
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University Of Toronto
The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in Scarborough and Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major rankings, the university consistently ranks in the top ten public universities in the world and as the top university ...
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Peter Yates
Peter James Yates (24 July 1929 – 9 January 2011) was an English film director and producer. Biography Early life Yates was born in Aldershot, Hampshire. The son of an army officer, he attended Charterhouse School as a boy, graduated from the Royal Academy of Dramatic Art and worked for some years as an actor, director and stage manager. He directed plays in London and New York. He also spent two years as racing manager for Stirling Moss and Peter Collins. Early film industry jobs and assistant director In the 1950s he started in the film industry doing odd jobs such as dubbing foreign films and editing documentaries. He eventually became a leading assistant director. He was an assistant director to Mark Robson on ''The Inn of the Sixth Happiness'' (1958), Terence Young on ''Serious Charge'' (1959) with Cliff Richard, Terry Bishop on '' Cover Girl Killer'' (1959), Guy Hamilton on ''A Touch of Larceny'' (1960), Jack Cardiff on ''Sons and Lovers'' (1960), Tony Richardson ...
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Heterocyclic Compound
A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of these heterocycles. Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related materials), and many natural and synthetic dyes. More than half of known compounds are heterocycles. 59% of US FDA-approved drugs contain nitrogen heterocycles. Classification The study of heterocyclic chemistry focuses especially on unsaturated derivatives, and the preponderance of work and applications involves unstrained 5- and 6-membered rings. Included are pyridine, thiophene, pyrrole, and furan. Another large class of heterocycles refers to those fused to benzene rings. For example, the fused benzene derivatives of pyridine, thiophene, pyrrole, and furan are quinol ...
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Eliot Stellar
Eliot Stellar (November 1, 1919 – October 12, 1993) was an American a physiological psychologist noted for his research of the physiological processes of the brain and how they affect motivation and behavior. The National Academy of Sciences called him "one of the founders of ... behavioral neuroscience". Stellar was a provost at the University of Pennsylvania, a member of the National Academy of Sciences and the president of the Academy's the Human Rights Committee, president of the Eastern Psychological Association, president of the American Philosophical Society, a recipient of the Warren Medal of the Society of Experimental Physiologists and of the American Psychological Foundation's Gold Medal for Lifetime Achievement. Chronology * November 1, 1919: born in Boston, Massachusetts * 1941: graduated from Harvard University * 1942: M.S., Brown University * 1947: Ph.D., Brown University * 1947-1960: faculty positions at Johns Hopkins University * 1960-1965: professor of phys ...
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Vartan Gregorian
Vartan Gregorian; fa, وارتان گرگوریان (April 8, 1934 – April 15, 2021) was an Armenian-American academic, educator, and historian. He served as president of the Carnegie Corporation from 1997 to 2021. An Armenian born in Iran, Gregorian moved to the United States at 22. He graduated with a PhD from Stanford University. He subsequently taught at several universities and his work as a historian focused mainly on the Muslim world. He went on to join the University of Pennsylvania faculty, then as its provost. From 1981 to 1989 he served as president of the New York Public Library during which he succeeded in financially stabilizing the institution and revitalizing its cultural importance. From 1989 to 1997 he served as the first foreign-born president of Brown University. Gregorian's work has been widely acknowledged. He received dozens of honorary doctorates, the National Humanities Medal (1998), and the Presidential Medal of Freedom (2004). Early life and educ ...
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Mildred Cohn
Mildred Cohn (July 12, 1913 – October 12, 2009) was an American biochemist who furthered understanding of biochemical processes through her study of chemical reactions within animal cells. She was a pioneer in the use of nuclear magnetic resonance for studying enzyme reactions, particularly reactions of adenosine triphosphate (ATP). She received the nation's highest science award, the National Medal of Science, in 1982, and was inducted into the National Women's Hall of Fame. Early life Cohn's parents, childhood sweethearts Isidore Cohn and Bertha Klein Cohn, were Jewish. Her father was a rabbi. They left Russia for the United States around 1907. Mildred Cohn was born July 12, 1913, in the Bronx, where her family lived in an apartment. When Mildred was 13, her father moved the family to a Yiddish-speaking cooperative, ''Heim Gesellschaft'', which strongly emphasized education, the arts, social justice, and the preservation of Yiddish culture.Mildred Cohn, Ph.D.: The Sc ...
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University Of Maryland
The University of Maryland, College Park (University of Maryland, UMD, or simply Maryland) is a public land-grant research university in College Park, Maryland. Founded in 1856, UMD is the flagship institution of the University System of Maryland. It is also the largest university in both the state and the Washington metropolitan area, with more than 41,000 students representing all fifty states and 123 countries, and a global alumni network of over 388,000. Together, its 12 schools and colleges offer over 200 degree-granting programs, including 92 undergraduate majors, 107 master's programs, and 83 doctoral programs. UMD is a member of the Association of American Universities and competes in intercollegiate athletics as a member of the Big Ten Conference. The University of Maryland's proximity to the nation's capital has resulted in many research partnerships with the federal government; faculty receive research funding and institutional support from many agencies, such ...
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Allan R
Allan may refer to: People * Allan (name), a given name and surname, including list of people and characters with this name * Allan (footballer, born 1984) (Allan Barreto da Silva), Brazilian football striker * Allan (footballer, born 1989) (Allan dos Santos Natividade), Brazilian football forward * Allan (footballer, born 1991) (Allan Marques Loureiro), Brazilian football midfielder * Allan (footballer, born 1994) (Allan Christian de Almeida), Brazilian football midfielder * Allan (footballer, born 1997) (Allan Rodrigues de Souza), Brazilian football midfielder Places * Allan, Queensland, Australia * Allan, Saskatchewan, Canada * Allan, the Allaine river's lower course, in France * Allan, Drôme, town in France * Allan, Iran (other), places in Iran Other uses * Allan, a Clan Grant split (or sept) * Ahlawat or Allan, an ethnic clan in India * ''Allan'', a 1966 film directed by Donald Shebib * "Allan" (song), a 1988 song recorded by the French artist Mylène Farmer ...
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