MRC Human Genetics Unit
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MRC Human Genetics Unit
The Medical Research Council (UK) Human Genetics Unit is situated at the Western General Hospital in Edinburgh. It is one of the largest MRC research establishments, housing over two hundred scientists, support staff, research fellows, PhD students, and visiting workers. Staff current and former staff at the MRC HGU include: Directors * 1956–1969 Dr Michael Court Brown * 1969–1994 Professor John Evans * 1994–2015 Professor Nicholas Hastie * 2015– Professor Wendy Bickmore Group leaders * Pleasantine Mill * Chris Ponting Sections The Human Genetics Unit is divided into three sections: Biomedical Genomics -Research harnesses the power of large genome-size and population data to reveal the complex nature of disease processes. Section Head: Professor Chris Ponting Genome Regulation -Research focuses on mechanisms that maintain the stability of the genome between cells and between generations, regulate the expression of genes and how changes to these contribute to dis ...
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Wendy Bickmore
Wendy Anne Bickmore (born 28 July 1961) is a British genome biologist known for her research on the organisation of genomic material in cells. Early life and education Bickmore was born at Shoreham-by-Sea on 28 July 1961 to Beryl and Keith Bickmore. She was educated at Chichester High School For Girls and obtained an undergraduate Bachelor of Arts degree in biochemistry from the University of Oxford and her PhD from the University of Edinburgh for research analysing nucleic acid sequences from the Y chromosome of humans supervised by Howard Cooke and Adrian Bird. Career Bickmore’s interest in science began as a teen being influenced by her biology teacher and her parents who were keen amateur gardeners. Her interest in biochemistry was confirmed having read ‘The Chemistry of Life’ by Steven Rose and she went on to study biochemistry at university. Her Ph.D. research examined DNA sequences from the Y chromosome in humans. She was an independent fellow at the Lister In ...
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Website
A website (also written as a web site) is a collection of web pages and related content that is identified by a common domain name and published on at least one web server. Examples of notable websites are Google Search, Google, Facebook, Amazon (website), Amazon, and Wikipedia. All publicly accessible websites collectively constitute the World Wide Web. There are also private websites that can only be accessed on a intranet, private network, such as a company's internal website for its employees. Websites are typically dedicated to a particular topic or purpose, such as news, education, commerce, entertainment or social networking. Hyperlinking between web pages guides the navigation of the site, which often starts with a home page. User (computing), Users can access websites on a range of devices, including desktop computer, desktops, laptops, tablet computer, tablets, and smartphones. The application software, app used on these devices is called a Web browser. History ...
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Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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Western General Hospital
The Western General Hospital (often abbreviated to simply ‘The Western General’) is a health facility at Craigleith, Edinburgh, Scotland. It is managed by NHS Lothian. History The hospital was designed by Peddie and Kinnear and opened as the St. Cuthberts and Canongate Poorhouse in 1868, principally as a workhouse but also having some hospital functions. It was later renamed Craigleith Poorhouse. In 1915, during the First World War, the building was requisitioned by the War Office to create the 2nd Scottish General Hospital, a facility for the Royal Army Medical Corps to treat military casualties. After returning to poorhouse use in 1920 it was converted fully to hospital use in 1927. A nurses' home was added in 1935 and a pathology block was completed in 1939. It joined the National Health Service in 1948 and a new library was completed in 1979. The first Maggie's Cancer Caring Centre opened on the Western General Hospital site in 1996. In June 2012 the Medicine for the ...
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Edinburgh
Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian on the southern shore of the Firth of Forth. Edinburgh is Scotland's List of towns and cities in Scotland by population, second-most populous city, after Glasgow, and the List of cities in the United Kingdom, seventh-most populous city in the United Kingdom. Recognised as the capital of Scotland since at least the 15th century, Edinburgh is the seat of the Scottish Government, the Scottish Parliament and the Courts of Scotland, highest courts in Scotland. The city's Holyrood Palace, Palace of Holyroodhouse is the official residence of the Monarchy of the United Kingdom, British monarchy in Scotland. The city has long been a centre of education, particularly in the fields of medicine, Scots law, Scottish law, literature, philosophy, the sc ...
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Nicholas Hastie
Professor Nicholas Dixon Hastie (born 1947) CBE, FRS, FRSE is a British geneticist, and former Director of the MRC Human Genetics Unit at the University of Edinburgh. Education Hastie was educated at the University of Liverpool and the University of Cambridge. Awards and honours Hastie was elected a Fellow of the Royal Society in 2002. His nomination reads Hastie was also a member of the Faculty of 1000 F1000 (formerly "Faculty of 1000") is an open research publisher for scientists, scholars, and clinical researchers. F1000 offers a different research evaluation service from standard academic journals by offering peer-review after, rather than .... References {{DEFAULTSORT:Hastie, Nicholas British geneticists Commanders of the Order of the British Empire Fellows of the Royal Society Fellows of the Royal Society of Edinburgh Living people 1947 births Alumni of the University of Liverpool ...
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Pleasantine Mill
Pleasantine Mill is a cell biologist and group leader at the MRC Human Genetics Unit at the University of Edinburgh. She won the 2018 British Society for Cell Biology Women in Cell Biology Early Career Medal. Early life and education Mill completed her bachelor's degree at McGill University in 1999. She joined University of Toronto for her PhD, working on transcription factors in the Hedgehog signaling pathway in skin development and tumorigenesis supervised by Chi-chung Hui. Her work contributed to the book ''Hedgehog-Gli Signaling in Human Disease.'' She worked at the Hospital for Sick Children and earned her PhD in 2004. Career and research Mill was awarded a Canadian Natural Sciences and Engineering Research Council (NSERC) postdoctoral research fellowship to join the Medical Research Council (MRC) Human Genetics Unit (HGU). She worked on mouse mutagenesis. During her postdoctoral work she identified several novel mutant lines that disrupted developmental signalling ...
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Chris Ponting
Christopher Paul Ponting is a British computational biologist, specializing in the evolution and function of genes and genomes. He is currently Chair of Medical Bioinformatics at the University of Edinburgh and group leader in the MRC Human Genetics Unit. He is also an Associate Faculty member of the Wellcome Trust Sanger Institute, a Fellow of the Academy of Medical Sciences, member of the European Molecular Biology Organisation and Fellow of the Royal Society of Edinburgh. His research focuses on long noncoding RNA function and evolution, on single cell biology and on disease genomics. Outside of science, Chris is an amateur novelist and wrote an unpublished, science fiction novel about engineered viruses.The Bioinformatics CRO Podcast'. Episode 2, 2020. Education After receiving his Bachelor of Arts and Master of Science in physics from University of Oxford and the University of British Columbia, respectively, he returned to Oxford, completing his Doctor of Philosophy in bi ...
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University Of Edinburgh
The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played an important role in Edinburgh becoming a chief intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the " Athens of the North." Edinburgh is ranked among the top universities in the United Kingdom and the world. Edinburgh is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2021, it had a total income of £1.176 billion, of ...
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Cancer Research UK
Cancer Research UK (CRUK) is the world's largest independent cancer research organization. It is registered as a charity in the United Kingdom and Isle of Man, and was formed on 4 February 2002 by the merger of The Cancer Research Campaign and the Imperial Cancer Research Fund. Cancer Research UK conducts research using both its own staff and grant-funded researchers. It also provides information about cancer and runs campaigns aimed at raising awareness and influencing public policy. The organisation's work is almost entirely funded by the public. It raises money through donations, legacies, community fundraising, events, retail and corporate partnerships. Over 40,000 people are regular volunteers. History The Imperial Cancer Research Fund (ICRF) was founded in 1902 as the Cancer Research Fund, changing its name to the Imperial Cancer Research Fund in 1904. It grew over the next twenty years to become one of the world's leading cancer research charities. Its flagship laborato ...
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Genetics In The United Kingdom
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context ...
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Genetics Or Genomics Research Institutions
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinians, Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Phenotypic trait, Trait inheritance and Molecular genetics, molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the Cell (biolo ...
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