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Multiscale Electrophysiology Format
Multiscale Electrophysiology Format (MEF) was developed to handle the large amounts of data produced by large-scale electrophysiology in human and animal subjects. MEF can store any time series data up to 24 bits in length, and employs lossless range encoded difference compression. Subject identifying information in the file header can be encrypted using 128-bit AES encryption in order to comply with HIPAA requirements for patient privacy when transmitting data across an open network. Compressed data is stored in independent blocks to allow direct access to the data, facilitate parallel processing and limit the effects of potential damage to files. Data fidelity is ensured by a 32-bit cyclic redundancy check in each compressed data block using the Koopman polynomial (0xEB31D82E), which has a Hamming distance of from 4 to 114 kbits. A formal specification and source code are available online. MEF_import is an EEGLAB plugin to import MEF data into EEGLAB. See also * Range encodin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophysiology
Electrophysiology (from Greek , ''ēlektron'', "amber" etymology of "electron"">Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , '' -logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions (ion current) in biologi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRC-32
A cyclic redundancy check (CRC) is an error-detecting code commonly used in digital networks and storage devices to detect accidental changes to digital data. Blocks of data entering these systems get a short ''check value'' attached, based on the remainder of a polynomial division of their contents. On retrieval, the calculation is repeated and, in the event the check values do not match, corrective action can be taken against data corruption. CRCs can be used for error correction (see bitfilters). CRCs are so called because the ''check'' (data verification) value is a ''redundancy'' (it expands the message without adding information) and the algorithm is based on ''cyclic'' codes. CRCs are popular because they are simple to implement in binary hardware, easy to analyze mathematically, and particularly good at detecting common errors caused by noise in transmission channels. Because the check value has a fixed length, the function that generates it is occasionally used as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotechnology
Neurotechnology encompasses any method or electronic device which interfaces with the nervous system to monitor or modulate neural activity. Common design goals for neurotechnologies include using neural activity readings to control external devices such as neuroprosthetics, altering neural activity via neuromodulation to repair or normalize function affected by neurological disorders, or augmenting cognitive abilities. In addition to their therapeutic or commercial uses, neurotechnologies also constitute powerful research tools to advance fundamental neuroscience knowledge. Some examples of neurotechnologies include deep brain stimulation, photostimulation based on optogenetics and photopharmacology, transcranial magnetic stimulation, and brain–computer interfaces, such as cochlear implants and retinal implants. Background The field of neurotechnology has been around for nearly half a century but has only reached maturity in the last twenty years. The advent of brain imaging ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurophysiology
Neurophysiology is a branch of physiology and neuroscience that studies nervous system function rather than nervous system architecture. This area aids in the diagnosis and monitoring of neurological diseases. Historically, it has been dominated by electrophysiology—the electrical recording of neural activity ranging from the molar (the electroencephalogram, EEG) to the cellular (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field potentials. However, since the neurone is an electrochemical machine, it is difficult to isolate electrical events from the metabolic and molecular processes that cause them. Thus, neurophysiologists currently utilise tools from chemistry (calcium imaging), physics (functional magnetic resonance imaging, Functional magnetic resonance imaging, fMRI), and molecular biology (site directed mutations) to examine brain activity. The word originates f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrophysiology
Electrophysiology (from Greek , ''ēlektron'', "amber" etymology of "electron"">Electron#Etymology">etymology of "electron" , ''physis'', "nature, origin"; and , '' -logia'') is the branch of physiology that studies the electrical properties of biological cells and tissues. It involves measurements of voltage changes or electric current or manipulations on a wide variety of scales from single ion channel proteins to whole organs like the heart. In neuroscience, it includes measurements of the electrical activity of neurons, and, in particular, action potential activity. Recordings of large-scale electric signals from the nervous system, such as electroencephalography, may also be referred to as electrophysiological recordings. They are useful for electrodiagnosis and monitoring. Definition and scope Classical electrophysiological techniques Principle and mechanisms Electrophysiology is the branch of physiology that pertains broadly to the flow of ions (ion current) in biologi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electroencephalography
Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex and allocortex. It is typically non-invasive, with the EEG electrodes placed along the scalp (commonly called "scalp EEG") using the International 10-20 system, or variations of it. Electrocorticography, involving surgical placement of electrodes, is sometimes called " intracranial EEG". Clinical interpretation of EEG recordings is most often performed by visual inspection of the tracing or quantitative EEG analysis. Voltage fluctuations measured by the EEG bioamplifier and electrodes allow the evaluation of normal brain activity. As the electrical activity monitored by EEG originates in neurons in the underlying brain tissue, the recordings made by the electrodes on the surface of the scalp vary in accordance with their orientation and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Interlanguage Links
An interlanguage is an idiolect that has been developed by a learner of a second language (L2) which preserves some features of their first language (L1), and can also overgeneralize some L2 writing and speaking rules. These two characteristics of an interlanguage result in the system's unique linguistic organization. An interlanguage is idiosyncratically based on the learners' experiences with the L2. It can "fossilize", or cease developing, in any of its developmental stages. It is claimed that several factors shape interlanguage rules, including L1 transfer, previous learning strategies, strategies of L2 acquisition, L2 communication strategies, and overgeneralization of L2 language patterns. Interlanguage is based on the theory that there is a dormant psychological framework in the human brain that is activated when one attempts to learn a second language. Interlanguage theory is often credited to Larry Selinker, who coined the terms "interlanguage" and "fossilization." Ur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AES Encryption
The Advanced Encryption Standard (AES), also known by its original name Rijndael (), is a specification for the encryption of electronic data established by the U.S. National Institute of Standards and Technology (NIST) in 2001. AES is a variant of the Rijndael block cipher developed by two Belgian cryptographers, Joan Daemen and Vincent Rijmen, who submitted a proposal to NIST during the AES selection process. Rijndael is a family of ciphers with different key and block sizes. For AES, NIST selected three members of the Rijndael family, each with a block size of 128 bits, but three different key lengths: 128, 192 and 256 bits. AES has been adopted by the U.S. government. It supersedes the Data Encryption Standard (DES), which was published in 1977. The algorithm described by AES is a symmetric-key algorithm, meaning the same key is used for both encrypting and decrypting the data. In the United States, AES was announced by the NIST as U.S. FIPS PUB 197 (FIPS 197) on November ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lossless Data Compression
Lossless compression is a class of data compression that allows the original data to be perfectly reconstructed from the compressed data with no loss of information. Lossless compression is possible because most real-world data exhibits statistical redundancy. By contrast, lossy compression permits reconstruction only of an approximation of the original data, though usually with greatly improved compression rates (and therefore reduced media sizes). By operation of the pigeonhole principle, no lossless compression algorithm can efficiently compress all possible data. For this reason, many different algorithms exist that are designed either with a specific type of input data in mind or with specific assumptions about what kinds of redundancy the uncompressed data are likely to contain. Therefore, compression ratios tend to be stronger on human- and machine-readable documents and code in comparison to entropic binary data (random bytes). Lossless data compression is used in many ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Range Encoding
Range coding (or range encoding) is an entropy coding method defined by G. Nigel N. Martin in a 1979 paper,, 100000)) using the probability distribution . The encoder breaks down the range [0, 100000) into three subranges: A: [ 0, 60000) B: [ 60000, 80000) : [ 80000, 100000) Since our first symbol is an A, it reduces our initial range down to [0, 60000). The second symbol choice leaves us with three sub-ranges of this range. We show them following the already-encoded 'A': AA: [ 0, 36000) AB: [ 36000, 48000) A: [ 48000, 60000) With two symbols encoded, our range is now [0, 36000) and our third symbol leads to the following choices: AAA: [ 0, 21600) AAB: [ 21600, 28800) AA: [ 28800, 36000) This time it is the second of our three choices that represent the message we want to encode, and our range becomes [21600, 28800). It may look harder to determine our sub-ranges in this case, but it is actually not: we can mere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hamming Distance
In information theory, the Hamming distance between two strings of equal length is the number of positions at which the corresponding symbols are different. In other words, it measures the minimum number of ''substitutions'' required to change one string into the other, or the minimum number of ''errors'' that could have transformed one string into the other. In a more general context, the Hamming distance is one of several string metrics for measuring the edit distance between two sequences. It is named after the American mathematician Richard Hamming. A major application is in coding theory, more specifically to block codes, in which the equal-length strings are vectors over a finite field. Definition The Hamming distance between two equal-length strings of symbols is the number of positions at which the corresponding symbols are different. Examples The symbols may be letters, bits, or decimal digits, among other possibilities. For example, the Hamming distance between: ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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