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Momordin Ia
Momordin may be one of two classes of chemicals found in certain plants: * Momordin (saponin), a derivative of the triterpenoid oleanic acid * Momordin (protein) Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibit ..., an enzymatic protein that inactivates ribosomes See also * '' Momordica'', a plant genus that yields momordins of both kinds. {{disamb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin (saponin)
Momordin is one of several saponins derived from oleanolic acid, a triterpenoid. These chemical compounds are found in some plants of the genus ''Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''), as well as in other Asian herbal medicine plants such as ''Kochia scoparia'' and ''Ampelopsis radix''. Momordins include: * Momordin I, oleanolic acid 3-''O''-α-''L''-arabinopyranosyl(1→3)-β-D-glucuronopyranoside. A white powder that decomposes at 235–240 °C. Found in the root of ''Momordica cochinchinensis'' where it constitutes 10% of the dried methanol extract. * Momordin Ia, from ''M. cochinchinensis''. * Momordin Ib, from ''M. cochinchinensis''. * Momordin Ic or (3β)-17-carboxy-28-norolean-12-en-3-yl 3'-''O''-(β-D-xylopyranosyl)-β-D-glucuronide (), CAS number 96990-18-0. It is obtained as colorless fine crystals that decompose at 240 °C. It inhibits gastric emptying in mice. * Momordin Id, from ''M. cochinchi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Momordin (protein)
Momordin or α-momorcharin is one of several related proteins isolated from several plants of the genus '' Momordica'', which includes the bitter melon (''M. charantia'') and the balsam apple (''M. balsamina''). These enzymes are potent inhibitor of protein synthesis in eukaryotes by inactivating the ribosomes. However its cytotoxic activity is limited because it is not taken up by the cells; it has to be chemically modified to do so. There are several variants, including momordin II (from ''M. balsamina'') and momordin-a (from ''M. charantia''). See also * Momordin (saponin), an unrelated compound (a saponin of the triterpenoid Triterpenes are a class of chemical compounds composed of three terpene units with the molecular formula C30H48; they may also be thought of as consisting of six isoprene units. Animals, plants and fungi all produce triterpenes, including squale ... oleanic acid). References Ribosome-inactivating proteins {{protein-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
