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Mike Youle
Michael (Mike) Simon Youle (born 1960) is a British doctor and clinical researcher specializing in HIV treatment. He publicised the concept of pre-exposure prophylaxis (PREP) for HIV and has studied the health economics of HIV therapy. In 1995, he was listed as one of 40 influential gay men by ''The Independent''. Education and career Youle qualified at Sheffield Medical School in 1984. One of the founders of the Kobler Clinic of Chelsea & Westminster Hospital in London, the earliest specialist centre combining HIV care and research in the UK, he was the centre's Clinical Trials Co-ordinator from 1986 to 1996. In 1990–91, he served as a consultant for the World Health Organization's Global Programme on AIDS and the National Programme on AIDS in Kampala. Youle has been Director of HIV Clinical Research at the Royal Free Hospital in London and Honorary Senior Lecturer in Public Health at the Royal Free & University College Medical School (now UCL Medical School) since 1996. He held ...
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Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ...
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Ageing
Ageing ( BE) or aging ( AE) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. In a broader sense, ageing can refer to single cells within an organism which have ceased dividing, or to the population of a species. In humans, ageing represents the accumulation of changes in a human being over time and can encompass physical, psychological, and social changes. Reaction time, for example, may slow with age, while memories and general knowledge typically increase. Ageing increases the risk of human diseases such as cancer, Alzheimer's disease, diabetes, cardiovascular disease, stroke and many more. Of the roughly 150,000 people who die each day across the globe, about two-thirds die from age-related causes. Current ageing theories are assigned to the damage concept, whereby the accumulation of damage (such as DNA ox ...
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HIV/AIDS Researchers
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS). This stage is often also associated with unintended weight loss. HIV is spread primarily by unprotected sex (including anal and vaginal sex), contaminated blood transfusions, hypodermic needles, and from mother to child during ...
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Academics Of University College London
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, d ...
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Alumni Of The University Of Sheffield
Alumni (singular: alumnus (masculine) or alumna (feminine)) are former students of a school, college, or university who have either attended or graduated in some fashion from the institution. The feminine plural alumnae is sometimes used for groups of women. The word is Latin and means "one who is being (or has been) nourished". The term is not synonymous with "graduate"; one can be an alumnus without graduating (Burt Reynolds, alumnus but not graduate of Florida State, is an example). The term is sometimes used to refer to a former employee or member of an organization, contributor, or inmate. Etymology The Latin noun ''alumnus'' means "foster son" or "pupil". It is derived from PIE ''*h₂el-'' (grow, nourish), and it is a variant of the Latin verb ''alere'' "to nourish".Merriam-Webster: alumnus
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21st-century English Medical Doctors
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ...
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PharmacoEconomics (journal)
Pharmacoeconomics refers to the scientific discipline that compares the value of one pharmaceutical drug or drug therapy to another. It is a sub-discipline of health economics. A pharmacoeconomic study evaluates the cost (expressed in monetary terms) and effects (expressed in terms of monetary value, efficacy or enhanced quality of life) of a pharmaceutical product. Pharmacoeconomic studies serve to guide optimal healthcare resource allocation, in a standardized and scientifically grounded manner. Economic evaluation Pharmacoeconomics centers on the economic evaluation of pharmaceuticals, and can use cost-minimization analysis, cost-benefit analysis, cost-effectiveness analysis or cost-utility analysis. Quality-adjusted life years have become the dominant outcome of interest in pharmacoeconomic evaluations, and many studies employ a cost-per-QALY analysis. Economic evaluations are carried out alongside randomized controlled trials and using methods of decision-analytic model ...
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Journal Of The International Association Of Physicians In AIDS Care
The ''Journal of the International Association of Providers of AIDS Care'' is a bimonthly peer-reviewed medical journal that covers research on AIDS. The editor-in-chief is Jose M. Zuniga (International Association of Providers of AIDS Care). The journal was established in 2002 and is published by SAGE Publications. Abstracting and indexing The journal is abstracted and indexed in: * CAB Abstracts * CINAHL * EBSCO databases * Global Health * MEDLINE * Rural Development Abstracts * Tropical Diseases Bulletin CAB Direct is a source of references for the '' applied life sciences'' It incorporates two bibliographic databases: ''CAB Abstracts'' and ''Global Health''. CAB Direct is an access point for multiple bibliographic databases produced by ''CABI' ... External links * SAGE Publishing academic journals English-language journals HIV/AIDS journals Academic journals established in 2002 Bimonthly journals Academic journals associated with learned and professional socie ...
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Churchill Livingstone
Churchill Livingstone is an academic publisher. It was formed in 1971 from the merger of Longman's medical list, E & S Livingstone (Edinburgh, Scotland) and J & A Churchill (London, England) and was owned by Pearson. Harcourt acquired Churchill Livingstone in 1997. It is now integrated as an imprint in Elsevier's health science division after Elsevier acquired Harcourt in 2001. In the past it published a number of classic medical texts, including Sir William Osler's textbook '' The Principles and Practice of Medicine, Gray's Anatomy,'' and ''Myles In Greek mythology, Myles (; Ancient Greek: Μύλης means 'mill-man') was an ancient king of Laconia. He was the son of the King Lelex and possibly the naiad Queen Cleocharia, and brother of Polycaon. Myles was the father of Eurotas who begott ...' Textbook for Midwives.'' In the 1980s, in addition to new texts in all areas of clinical medicine, it published an extensive list of medical and nursing textbooks in low-cost editions ...
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Wiley-Blackwell
Wiley-Blackwell is an international scientific, technical, medical, and scholarly publishing business of John Wiley & Sons. It was formed by the merger of John Wiley & Sons Global Scientific, Technical, and Medical business with Blackwell Publishing in 2007.About Wiley-Blackwell
John Wiley & Sons, Inc.
Wiley-Blackwell is now an imprint that publishes a diverse range of academic and professional fields, including , , ,

Gay Man's Guide To Safer Sex
''Gay Man's Guide to Safer Sex'' is the name of a safer sex instructional documentary produced by Mike Esser and Tony Carne of Pride Video in association with the Terrence Higgins Trust in 1992. The film was directed by David Lewis and featured a soundtrack by John Balance and Peter Christopherson of Coil. The medical information included in the film is presented by Mike Youle, a British doctor specialising in HIV treatment. In 1997 a sequel was released, directed by Robert Falconer. ''Gay Man's Guide to Safer Sex '97'' featured a radical recut of some of the original scenes asking the British Board of Film Classification to look again at what was permissible and becoming one of the first programmes to discuss the breakthrough of Triple Combination Therapy and the ramifications and personal experiences of living with HIV. The medical information and discussion was again led by Mike Youle. The 1997 film was released on retail video in the UK and USA and later on DVD. It is still in ...
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Safer Sex
In cryptography, SAFER (Secure And Fast Encryption Routine) is the name of a family of block ciphers designed primarily by James Massey (one of the designers of IDEA) on behalf of Cylink Corporation. The early SAFER K and SAFER SK designs share the same encryption function, but differ in the number of rounds and the key schedule. More recent versions — SAFER+ and SAFER++ — were submitted as candidates to the AES process and the NESSIE project respectively. All of the algorithms in the SAFER family are unpatented and available for unrestricted use. SAFER K and SAFER SK The first SAFER cipher was SAFER K-64, published by Massey in 1993, with a 64-bit block size. The "K-64" denotes a key size of 64 bits. There was some demand for a version with a larger 128-bit key, and the following year Massey published such a variant incorporating new key schedule designed by the Singapore Ministry for Home affairs: SAFER K-128. However, both Lars Knudsen and Sean Murphy found minor ...
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