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Mieczysław Mąkosza
Mieczysław Józef Mąkosza (born 16 November 1934) is a Polish chemist specializing in organic synthesis and investigation of organic mechanisms. Along with Jerzy Winiarski he is credited for the discovery of the aromatic vicarious nucleophilic substitution, VNS. He also contributed to the discovery of phase transfer catalysis reactions. From 1979 to 2005 he was director of the Institute of Organic Chemistry of the Polish Academy of Sciences The Polish Academy of Sciences ( pl, Polska Akademia Nauk, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of .... References 1934 births Polish chemists Living people Recipients of the State Award Badge (Poland) {{Poland-scientist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Synthesis
Organic synthesis is a special branch of chemical synthesis and is concerned with the intentional construction of organic compounds. Organic molecules are often more complex than inorganic compounds, and their synthesis has developed into one of the most important branches of organic chemistry. There are several main areas of research within the general area of organic synthesis: ''total synthesis'', ''semisynthesis'', and ''methodology''. Total synthesis A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available petrochemical or natural precursors. Total synthesis may be accomplished either via a linear or convergent approach. In a ''linear'' synthesis—often adequate for simple structures—several steps are performed one after another until the molecule is complete; the chemical compounds made in each step are called synthetic intermediates. Most often, each step in a synthesis refers to a separate rea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Warsaw University Of Technology
The Warsaw University of Technology ( pl, Politechnika Warszawska, lit=Varsovian Polytechnic) is one of the leading institutes of technology in Poland and one of the largest in Central Europe. It employs 2,453 teaching faculty, with 357 professors (including 145 titular professors). The student body numbers 36,156 (as of 2011), mostly full-time. There are 19 faculties (divisions) covering almost all fields of science and technology. They are in Warsaw, except for one in Płock. The Warsaw University of Technology has about 5,000 graduates per year. According to the 2008 ''Rzeczpospolita'' newspaper survey, engineers govern Polish companies. Warsaw Tech alums make up the highest percentage of Polish managers and executives. Every ninth president among the top 500 corporations in Poland is a graduate of the Warsaw University of Technology. Professor Kurnik, the rector, explained that the school provides a solid basis for the performance of managers by equipping its students with an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polish Academy Of Sciences
The Polish Academy of Sciences ( pl, Polska Akademia Nauk, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars and a network of research institutes. It was established in 1951, during the early period of the Polish People's Republic following World War II. History The Polish Academy of Sciences is a Polish state-sponsored institution of higher learning, headquartered in Warsaw, that was established by the merger of earlier science societies, including the Polish Academy of Learning (''Polska Akademia Umiejętności'', abbreviated ''PAU''), with its seat in Kraków, and the Warsaw Society of Friends of Learning (Science), which had been founded in the late 18th century. The Polish Academy of Sciences functions as a learned society acting through an elected assembly of leading scholars and research institutions. The Academy h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leningrad University
Saint Petersburg State University (SPBU; russian: Санкт-Петербургский государственный университет) is a public research university in Saint Petersburg, Russia. Founded in 1724 by a decree of Peter the Great, the university from the beginning has had a focus on fundamental research in science, engineering and humanities. During the Soviet period, it was known as Leningrad State University (russian: Ленинградский государственный университет). It was renamed after Andrei Zhdanov in 1948 and was officially called "Leningrad State University, named after A. A. Zhdanov and decorated with the Order of Lenin and the Order of the Red Banner of Labour." Zhdanov's was removed in 1989 and Leningrad in the name was officially replaced with Saint Petersburg in 1992. It is made up of 24 specialized faculties (departments) and institutes, the Academic Gymnasium, the Medical College, the College of Physical Culture ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vicarious Nucleophilic Substitution
In organic chemistry, the vicarious nucleophilic substitution is a special type of nucleophilic aromatic substitution in which a nucleophile replaces a hydrogen atom on the aromatic ring and not leaving groups such as halogen substituents which are ordinarily encountered in SNAr. This reaction type was reviewed in 1987 by Polish chemists Mieczysław Mąkosza and Jerzy Winiarski.''Synthesis of heterocyclic compounds via vicarious nucleophilic substitution of hydrogen'' Mieczysław Mąkosza Pure Appl. Chem., Vol. 69, No. 3, pp. 559-564, 1997''Article link It is typically encountered with nitroarenes and especially with nucleophiles, resulting in alkylated arenes: the new substituent can take the ''ortho'' or ''para'' positions, reversing the selectivity for the ''meta'' position that is usually observed with such compounds under electrophilic substitution. Carbon nucleophiles carry an electron-withdrawing group and a leaving group: the nucleophile attacks the aromatic ring, and exc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phase Transfer Catalysis
In chemistry, a phase-transfer catalyst or PTC is a catalyst that facilitates the transition of a reactant from one phase into another phase where reaction occurs. Phase-transfer catalysis is a special form of heterogeneous catalysis. Ionic reactants are often soluble in an aqueous phase but insoluble in an organic phase in the absence of the phase-transfer catalyst. The catalyst functions like a detergent for solubilizing the salts into the organic phase. Phase-transfer catalysis refers to the acceleration of the reaction upon the addition of the phase-transfer catalyst. By using a PTC process, one can achieve faster reactions, obtain higher conversions or yields, make fewer byproducts, eliminate the need for expensive or dangerous solvents that will dissolve all the reactants in one phase, eliminate the need for expensive raw materials and/or minimize waste problems. Phase-transfer catalysts are especially useful in green chemistry—by allowing the use of water, the nee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polish People
Poles,, ; singular masculine: ''Polak'', singular feminine: ''Polka'' or Polish people, are a West Slavic nation and ethnic group, who share a common history, culture, the Polish language and are identified with the country of Poland in Central Europe. The preamble to the Constitution of the Republic of Poland defines the Polish nation as comprising all the citizens of Poland, regardless of heritage or ethnicity. The majority of Poles adhere to Roman Catholicism. The population of self-declared Poles in Poland is estimated at 37,394,000 out of an overall population of 38,512,000 (based on the 2011 census), of whom 36,522,000 declared Polish alone. A wide-ranging Polish diaspora (the '' Polonia'') exists throughout Europe, the Americas, and in Australasia. Today, the largest urban concentrations of Poles are within the Warsaw and Silesian metropolitan areas. Ethnic Poles are considered to be the descendants of the ancient West Slavic Lechites and other tribes that inhabite ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vicarious Nucleophilic Substitution
In organic chemistry, the vicarious nucleophilic substitution is a special type of nucleophilic aromatic substitution in which a nucleophile replaces a hydrogen atom on the aromatic ring and not leaving groups such as halogen substituents which are ordinarily encountered in SNAr. This reaction type was reviewed in 1987 by Polish chemists Mieczysław Mąkosza and Jerzy Winiarski.''Synthesis of heterocyclic compounds via vicarious nucleophilic substitution of hydrogen'' Mieczysław Mąkosza Pure Appl. Chem., Vol. 69, No. 3, pp. 559-564, 1997''Article link It is typically encountered with nitroarenes and especially with nucleophiles, resulting in alkylated arenes: the new substituent can take the ''ortho'' or ''para'' positions, reversing the selectivity for the ''meta'' position that is usually observed with such compounds under electrophilic substitution. Carbon nucleophiles carry an electron-withdrawing group and a leaving group: the nucleophile attacks the aromatic ring, and exc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phase Transfer Catalysis
In chemistry, a phase-transfer catalyst or PTC is a catalyst that facilitates the transition of a reactant from one phase into another phase where reaction occurs. Phase-transfer catalysis is a special form of heterogeneous catalysis. Ionic reactants are often soluble in an aqueous phase but insoluble in an organic phase in the absence of the phase-transfer catalyst. The catalyst functions like a detergent for solubilizing the salts into the organic phase. Phase-transfer catalysis refers to the acceleration of the reaction upon the addition of the phase-transfer catalyst. By using a PTC process, one can achieve faster reactions, obtain higher conversions or yields, make fewer byproducts, eliminate the need for expensive or dangerous solvents that will dissolve all the reactants in one phase, eliminate the need for expensive raw materials and/or minimize waste problems. Phase-transfer catalysts are especially useful in green chemistry—by allowing the use of water, the nee ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gazeta Wyborcza
''Gazeta Wyborcza'' (; ''The Electoral Gazette'' in English) is a Polish daily newspaper based in Warsaw, Poland. It is the first Polish daily newspaper after the era of "real socialism" and one of Poland's newspapers of record, covering the gamut of political, international and general news from a liberal perspective. History and profile The ''Gazeta Wyborcza'' was first published on 8 May 1989, under the rhyming masthead motto, "''Nie ma wolności bez Solidarności''" ("There's no freedom without Solidarity"). The founders were Andrzej Wajda, Aleksander Paszyński and Zbigniew Bujak. Its founding was an outcome of the Polish Round Table Agreement between the communist government of the People's Republic of Poland and political opponents centred on the Solidarity movement. It was initially owned by Agora SA. Later the American company Cox Communications partially bought the daily. The paper was to serve as the voice of the Solidarity movement during the run-up to the 198 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1934 Births
Events January–February * January 1 – The International Telecommunication Union, a specialist agency of the League of Nations, is established. * January 15 – The 8.0 Nepal–Bihar earthquake strikes Nepal and Bihar with a maximum Mercalli intensity of XI (''Extreme''), killing an estimated 6,000–10,700 people. * January 26 – A 10-year German–Polish declaration of non-aggression is signed by Nazi Germany and the Second Polish Republic. * January 30 ** In Nazi Germany, the political power of federal states such as Prussia is substantially abolished, by the "Law on the Reconstruction of the Reich" (''Gesetz über den Neuaufbau des Reiches''). ** Franklin D. Roosevelt, President of the United States, signs the Gold Reserve Act: all gold held in the Federal Reserve is to be surrendered to the United States Department of the Treasury; immediately following, the President raises the statutory gold price from US$20.67 per ounce to $35. * February 6 – F ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
