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Michael Heidelberger
Michael Heidelberger (April 29, 1888 – June 25, 1991) was an American immunologist, often regarded as the father of modern immunology. He and Oswald Avery showed that the polysaccharides of pneumococcus are antigens, enabling him to show that antibodies are proteins. He spent most his early career at Columbia University and comparable time in his later years on the faculty of New York University. In 1934 and 1936 he received the Guggenheim Fellowship. In 1967 he received the National Medal of Science, and then he earned the Lasker Award for basic medical research in 1953 and again in 1978. His papers are held at the National Library of Medicine in Bethesda, Maryland. Early life Heidelberger was born in 1888 in New York City to a Jewish couple, David and Fannie Campe Heidelberger, a traveling salesman and a homemaker respectively. An older brother had died shortly after birth; a younger brother, Charles, was born 21 months after Michael. His paternal grandfather, also named Mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York City
New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the List of United States cities by population density, most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York (state), New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban area, urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous Megacity, megacities, and over 58 million people live within of the city. New York City is a global city, global Culture of New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oswald Avery
Oswald Theodore Avery Jr. (October 21, 1877 – February 20, 1955) was a Canadian-American physician and medical researcher. The major part of his career was spent at the Rockefeller Hospital in New York City. Avery was one of the first molecular biologists and a pioneer in immunochemistry, but he is best known for the experiment (published in 1944 with his co-workers Colin MacLeod and Maclyn McCarty) that isolated DNA as the material of which genes and chromosomes are made. The Nobel laureate Arne Tiselius said that Avery was the most deserving scientist not to receive the Nobel Prize for his work, though he was nominated for the award throughout the 1930s, 1940s, and 1950s. The lunar crater Avery was named in his honor. Early life and education Avery was born in Halifax, Nova Scotia in 1877 to Francis Joseph Avery, a Baptist minister, and his wife Elizabeth Crowdy. The couple had immigrated from Britain in 1873. Oswald Avery was born and grew up in a small wooden row h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marston Taylor Bogert
Marston Taylor Bogert (April 18, 1868 – March 21, 1954) was an American chemist. Biography He was born in Flushing, New York on April 18, 1868 and studied at the Flushing Institute, which was a well known private school, where he was a straight-A student. He entered Columbia College in New York in 1886 and graduated in 1890 with an A.B. degree. He entered the new Columbia School of Mines and gained a PhD in 1894. He stayed on to teach organic chemistry and in 1904 was appointed a full professor, retiring in 1939 as Emeritus Professor of Organic Chemistry in Residence. In 1893 he married Charlotte Hoogland. He was President of the American Chemical Society 1907-8 and President of the Society of Chemical Industry in 1912. During the First World War he served as a colonel in the US Chemical Warfare Service, and in the Second World War served on the Chemical Industry Branch of the War Production Board. He died in New York City on March 21, 1954. Honors and awards *1906: Awa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinazoline
Quinazoline is an organic compound with the formula C8H6N2. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring. It is a light yellow crystalline solid that is soluble in water. Also known as 1,3-diazanaphthalene, quinazoline received its name from being an aza derivative of quinoline. Though the parent quinazoline molecule is rarely mentioned by itself in technical literature, substituted derivatives have been synthesized for medicinal purposes such as antimalarial and anticancer agents. Quinazoline is a planar molecule. It is isomeric with the other diazanaphthalenes of the benzodiazine subgroup: cinnoline, quinoxaline, and phthalazine. Over 200 biologically active quinazoline and quinoline alkaloids are identified. Synthesis : The synthesis of quinazoline was first reported in 1895 by August Bischler and Lang through the decarboxylation of the 2-carboxy derivative (quinazoline-2-car ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes physical and chemical properties, and evaluation of chemical reactivity to understand their behavior. The study of organic reactions includes the chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical ( in silico) study. The range of chemicals studied in organic chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but also containing other elements, especially oxygen, nitrogen, sulfur, phosphorus (included in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clarinet
The clarinet is a musical instrument in the woodwind family. The instrument has a nearly cylindrical bore and a flared bell, and uses a single reed to produce sound. Clarinets comprise a family of instruments of differing sizes and pitches. The clarinet family is the largest such woodwind family, with more than a dozen types, ranging from the BB♭ contrabass to the E♭ soprano. The most common clarinet is the B soprano clarinet. German instrument maker Johann Christoph Denner is generally credited with inventing the clarinet sometime after 1698 by adding a register key to the chalumeau, an earlier single-reed instrument. Over time, additional keywork and the development of airtight pads were added to improve the tone and playability. Today the clarinet is used in classical music, military bands, klezmer, jazz, and other styles. It is a standard fixture of the orchestra and concert band. Etymology The word ''clarinet'' may have entered the English language via the Fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humanism
Humanism is a philosophical stance that emphasizes the individual and social potential and agency of human beings. It considers human beings the starting point for serious moral and philosophical inquiry. The meaning of the term "humanism" has changed according to the successive intellectual movements that have identified with it. During the Italian Renaissance, ancient works inspired scholars in various Italian cities, giving rise to a movement now called Renaissance humanism. With Enlightenment, humanistic values were re-enforced by the advances in science and technology, giving confidence to humans in their exploration of the world. By the early 20th century, organizations solely dedicated to humanism flourished in Europe and the United States, and have since expanded all over the globe. In the current day, the term generally refers to a focus on human well-being and advocates for human freedom, autonomy, and progress. It views humanity as responsible for the promotio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ethical Culture School
Ethical Culture Fieldston School (ECFS), also referred to as Fieldston, is a private independent school in New York City. The school is a member of the Ivy Preparatory School League. The school serves approximately 1,700 students with 480 faculty and staff. Joe Algrant is the Head of School. The school consists of four divisions: Ethical Culture, Fieldston Lower, Fieldston Middle, and Fieldston Upper. Ethical Culture, located on the Upper West Side of Manhattan, and Fieldston Lower, located on the Fieldston campus in the Riverdale section of the Bronx, serve Pre-K through 5th grade. The two lower schools feed into Fieldston Middle (6th–8th grades) and Fieldston Upper (9th–12th grades)—also located on the Fieldston campus in Riverdale. Ethical Culture is headed by Principal Rob Cousins, Fieldston Lower is headed by Principal Joe McCauley, Fieldston Middle is headed by Principal Jonathan Alschuler, and Fieldston Upper is headed by Principal Stacey Bobo. Tuition and fees for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Park
Central Park is an urban park in New York City located between the Upper West Side, Upper West and Upper East Sides of Manhattan. It is the List of New York City parks, fifth-largest park in the city, covering . It is the most visited urban park in the United States, with an estimated 42 million visitors annually , and is the most filmed location in the world. After proposals for a large park in Manhattan during the 1840s, it was approved in 1853 to cover . In 1857, landscape architects Frederick Law Olmsted and Calvert Vaux won a Architectural design competition, design competition for the park with their "Greensward Plan". Construction began the same year; existing structures, including a majority-Black settlement named Seneca Village, were seized through eminent domain and razed. The park's first areas were opened to the public in late 1858. Additional land at the northern end of Central Park was purchased in 1859, and the park was completed in 1876. After a period of de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guggenheim Fellowship
Guggenheim Fellowships are grants that have been awarded annually since by the John Simon Guggenheim Memorial Foundation to those "who have demonstrated exceptional capacity for productive scholarship or exceptional creative ability in the arts." Each year, the foundation issues awards in each of two separate competitions: * One open to citizens and permanent residents of the United States and Canada. * The other to citizens and permanent residents of Latin America and the Caribbean. The Latin America and Caribbean competition is currently suspended "while we examine the workings and efficacy of the program. The U.S. and Canadian competition is unaffected by this suspension." The performing arts are excluded, although composers, film directors, and choreographers are eligible. The fellowships are not open to students, only to "advanced professionals in mid-career" such as published authors. The fellows may spend the money as they see fit, as the purpose is to give fellows "b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York University
New York University (NYU) is a private research university in New York City. Chartered in 1831 by the New York State Legislature, NYU was founded by a group of New Yorkers led by then-Secretary of the Treasury Albert Gallatin. In 1832, the non-denominational all-male institution began its first classes near City Hall based on a curriculum focused on a secular education. The university moved in 1833 and has maintained its main campus in Greenwich Village surrounding Washington Square Park. Since then, the university has added an engineering school in Brooklyn's MetroTech Center and graduate schools throughout Manhattan. NYU has become the largest private university in the United States by enrollment, with a total of 51,848 enrolled students, including 26,733 undergraduate students and 25,115 graduate students, in 2019. NYU also receives the most applications of any private institution in the United States and admission is considered highly selective. NYU is organized int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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