Mexrenoic Acid
Mexrenoic acid, or mexrenoate, is a synthetic compound, synthetic steroidal antimineralocorticoid which was never marketed. See also * Mexrenoate potassium * Mexrenone References

Abandoned drugs Antimineralocorticoids Carboxylic acids Methyl esters Enones Pregnanes Spirolactones Tertiary alcohols {{steroid-stub ...
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Antimineralocorticoid
An antimineralocorticoid, also known as a mineralocorticoid receptor antagonist (MRA or MCRA) or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure. Spironolactone, the first member of the class, is also used in the management of hyperaldosteronism (including Conn's syndrome) and female hirsutism (due to additional antiandrogen actions). Most antimineralocorticoids, including spironolactone, are steroidal spirolactones. Finerenone is a nonsteroidal antimineralocorticoid. Medical uses Mineralocorticoid receptor antagonists are diuretic drugs that work primarily on the kidneys. They decrease sodium reabsorption which leads to increased water excretion by the kidneys. By regulating water excretion, mineralocorticoid receptor antagonists lower blood pressure and reduce fluid around t ...
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