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Metapneumovirus
''Metapneumovirus'' is a genus of viruses in the family ''Pneumoviridae''. The genus contains two species: * Avian metapneumovirus (aMPV) * Human metapneumovirus ''Human metapneumovirus'' (HMPV) is a negative-sense single-stranded RNA virus of the family ''Pneumoviridae'' and is closely related to the '' Avian metapneumovirus'' (AMPV) subgroup C. It was isolated for the first time in 2001 in the Netherlan ... (hMPV) References {{Taxonbar, from=Q16606632 Virus genera Pneumoviridae ...
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Human Metapneumovirus
''Human metapneumovirus'' (HMPV) is a negative-sense single-stranded RNA virus of the family ''Pneumoviridae'' and is closely related to the ''Avian metapneumovirus'' (AMPV) subgroup C. It was isolated for the first time in 2001 in the Netherlands by using the RAP-PCR (RNA arbitrarily primed PCR) technique for identification of unknown viruses growing in cultured cells. It is the second most common cause after ''Respiratory syncytial virus'' (RSV) of lower respiratory infection in young children. The peak age of hospitalization for infants with HMPV occurs between 6–12 months of age, slightly older than the peak of RSV, which is around 2–3 months. The clinical features and severity of HMPV are similar to those of RSV. HMPV is also an important cause of disease in older adults. Taxonomy Epidemiology HMPV is associated with 5% to 40% of respiratory tract infections in hospitalized and outpatient children. The virus is distributed worldwide and, in temperate regions, has a se ...
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Pneumoviridae
''Pneumoviridae'' (from Greek pneumo-, lung, -viridae, virus from Latin, poison, slimy liquid) is a family of negative-strand RNA viruses in the order ''Mononegavirales''. Humans, cattle, and rodents serve as natural hosts. Respiratory tract infections are associated with member viruses such as human respiratory syncytial virus. There are five species in the family which are divided between the genera ''Metapneumovirus'' and '' Orthopneumovirus''. The family used to be considered as a sub-family of ''Paramyxoviridae'', but has been reclassified as of 2016. Virology Structure Pneumoviruses are pleomorphic, capable of producing spherical and filamentous, enveloped virions (virus particles) that vary in size from 150 to 200 nm in diameter. The nucleocapsid consisting of a protein shell and viral nucleic acids has a helical symmetry. Nucleocapsids have a diameter of 13.5 nm and a helical pitch of 6.5 nm. Genome The genome is composed of negative-sense, singl ...
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Avian Metapneumovirus
Avian metapneumovirus (aMPV), also known as turkey rhinotracheitis or swollen head syndrome, causes a variety of disease syndromes in birds, depending on the bird species and virus type (A, B, C or D). First detected in 1978 in South Africa, the virus has spread all over the world except Australia. It is mostly found in turkeys, pheasants, Muscovy ducks and guinea fowls. Turkeys are the most susceptible species for all subtypes. It is presumed that other species are immune. Etiology AMPV belongs to the genus Metapneumovirus alongside human metapneumovirus, both of which belong to the family Pneumoviridae. The spherical formed particles are 100 to 500 nm in diameter and the filamentous formed are 100 nm in width. Most of the particles are not highly pleomorphic but rounded. The virus is divided into four subtypes from A to D, which can be classified by the attachment of glycoprotein (G-protein). Subtypes A, B and D are more closely related in Europe than to the su ...
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Genus
Genus ( plural genera ) is a taxonomic rank used in the biological classification of extant taxon, living and fossil organisms as well as Virus classification#ICTV classification, viruses. In the hierarchy of biological classification, genus comes above species and below family (taxonomy), family. In binomial nomenclature, the genus name forms the first part of the binomial species name for each species within the genus. :E.g. ''Panthera leo'' (lion) and ''Panthera onca'' (jaguar) are two species within the genus ''Panthera''. ''Panthera'' is a genus within the family Felidae. The composition of a genus is determined by taxonomy (biology), taxonomists. The standards for genus classification are not strictly codified, so different authorities often produce different classifications for genera. There are some general practices used, however, including the idea that a newly defined genus should fulfill these three criteria to be descriptively useful: # monophyly – all descendants ...
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Virus Genera
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, ...
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