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Merbecovirus
''Merbecovirus'' is a subgenus of viruses in the genus ''Betacoronavirus'', including the human pathogen Middle East respiratory syndrome–related coronavirus (MERS-CoV). The viruses in this subgenus were previously known as group 2c coronaviruses. Structure The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored. See also *''Embecovirus'' (group 2a) *''Sarbecovirus'' (group 2b) *''Nobecovirus ''Nobecovirus'' is a subgenus of viruses in the genus ''Betacoronavirus''. The viruses in the group were previously known as group 2d coronaviruses. Structure The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope ...'' (group 2d) References Virus subgenera Betacoronaviruses {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merbecovirus
''Merbecovirus'' is a subgenus of viruses in the genus ''Betacoronavirus'', including the human pathogen Middle East respiratory syndrome–related coronavirus (MERS-CoV). The viruses in this subgenus were previously known as group 2c coronaviruses. Structure The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored. See also *''Embecovirus'' (group 2a) *''Sarbecovirus'' (group 2b) *''Nobecovirus ''Nobecovirus'' is a subgenus of viruses in the genus ''Betacoronavirus''. The viruses in the group were previously known as group 2d coronaviruses. Structure The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope ...'' (group 2d) References Virus subgenera Betacoronaviruses {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MERS-CoV
''Middle East respiratory syndrome–related coronavirus'' (''MERS-CoV''), or EMC/2012 ( HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the DPP4 receptor. The species is a member of the genus ''Betacoronavirus'' and subgenus ''Merbecovirus''. Initially called simply novel coronavirus or nCoV, it was first reported in June 2012 after genome sequencing of a virus isolated from sputum samples from a person who fell ill in a 2012 outbreak of a new flu-like respiratory illness. By July 2015, MERS-CoV cases had been reported in over 21 countries, in Europe, North America and Asia as well as the Middle East. MERS-CoV is one of several viruses identified by the World Health Organization (WHO) as a likely cause of a future epidemic. They list it for urgent research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NeoCoV
''Middle East respiratory syndrome–related coronavirus'' (''MERS-CoV''), or EMC/2012 ( HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the DPP4 receptor. The species is a member of the genus ''Betacoronavirus'' and subgenus ''Merbecovirus''. Initially called simply novel coronavirus or nCoV, it was first reported in June 2012 after genome sequencing of a virus isolated from sputum samples from a person who fell ill in a 2012 outbreak of a new flu-like respiratory illness. By July 2015, MERS-CoV cases had been reported in over 21 countries, in Europe, North America and Asia as well as the Middle East. MERS-CoV is one of several viruses identified by the World Health Organization (WHO) as a likely cause of a future epidemic. They list it for urgent research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middle East Respiratory Syndrome–related Coronavirus
''Middle East respiratory syndrome–related coronavirus'' (''MERS-CoV''), or EMC/2012 ( HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the DPP4 receptor. The species is a member of the genus ''Betacoronavirus'' and subgenus ''Merbecovirus''. Initially called simply novel coronavirus or nCoV, it was first reported in June 2012 after genome sequencing of a virus isolated from sputum samples from a person who fell ill in a 2012 outbreak of a new flu-like respiratory illness. By July 2015, MERS-CoV cases had been reported in over 21 countries, in Europe, North America and Asia as well as the Middle East. MERS-CoV is one of several viruses identified by the World Health Organization (WHO) as a likely cause of a future epidemic. They list it for urgent research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Middle East Respiratory Syndrome-related Coronavirus
''Middle East respiratory syndrome–related coronavirus'' (''MERS-CoV''), or EMC/2012 ( HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The infecting virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the DPP4 receptor. The species is a member of the genus ''Betacoronavirus'' and subgenus ''Merbecovirus''. Initially called simply novel coronavirus or nCoV, it was first reported in June 2012 after genome sequencing of a virus isolated from sputum samples from a person who fell ill in a 2012 outbreak of a new flu-like respiratory illness. By July 2015, MERS-CoV cases had been reported in over 21 countries, in Europe, North America and Asia as well as the Middle East. MERS-CoV is one of several viruses identified by the World Health Organization (WHO) as a likely cause of a future epidemic. They list it for urgent researc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pipistrellus Bat Coronavirus HKU5
''Pipistrellus bat coronavirus HKU5'' (''Bat-CoV HKU5'') is an enveloped, positive-sense single-stranded RNA mammalian Group 2 ''Betacoronavirus'' discovered in Japanese ''Pipistrellus'' in Hong Kong. This strain of coronavirus is closely related to the newly identified novel MERS-CoV that is responsible for the 2012 ''Middle East respiratory syndrome-related coronavirus'' outbreaks in Saudi Arabia, Jordan, United Arab Emirates, the United Kingdom, France, and Italy. Transmission The exact means of transmission to humans is not yet well known. However, it has been demonstrated that betaCoV's including HKU5 have the propensity to recombine and cause interspecies transmission. However, this is not seen in Group C betaCov's to which MERS-CoV is most closely related. See also * London1 novel CoV/2012 * Severe acute respiratory syndrome Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coron ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hedgehog Coronavirus 1
''Hedgehog coronavirus 1'' is a mammalian Group C ''Betacoronavirus'', a positive-sense RNA virus, discovered in European hedgehogs (''Erinaceus europaeus'') from Germany and first described in 2014. Most ''Betacoronavirus'' clade c viruses are known from bats. The hedgehog is in the animal order Eulipotyphla, which is phylogenetically related to the bats, Chiroptera, so the researchers investigated faecal samples to look for coronaviruses. The virus was found in the highest concentrations in the lower gastrointestinal tract. See also *Animal viruses *MERS-CoV ''Middle East respiratory syndrome–related coronavirus'' (''MERS-CoV''), or EMC/2012 ( HCoV-EMC/2012), is the virus that causes Middle East respiratory syndrome (MERS). It is a species of coronavirus which infects humans, bats, and camels. The ... References {{Taxonbar, from=Q24808940 Merbecovirus Animal viral diseases Hedgehog diseases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Betacoronavirus
''Betacoronavirus'' (β-CoVs or Beta-CoVs) is one of four genera (''Alpha''-, ''Beta-'', '' Gamma-'', and '' Delta-'') of coronaviruses. Member viruses are enveloped, positive-strand RNA viruses that infect mammals (of which humans are part). The natural reservoir for betacoronaviruses are bats and rodents. Rodents are the reservoir for the subgenus ''Embecovirus'', while bats are the reservoir for the other subgenera. The coronavirus genera are each composed of varying viral lineages with the betacoronavirus genus containing four such lineages: A, B, C, D. In older literature, this genus is also known as "group 2 coronaviruses". The genus is in the subfamily ''Orthocoronavirinae'' in the family ''Coronaviridae'', of the order '' Nidovirales''. The betacoronaviruses of the greatest clinical importance concerning humans are OC43 and HKU1 (which can cause the common cold) of lineage A, SARS-CoV and SARS-CoV-2 (which has caused the disease COVID-19) of lineage B, and MERS-CoV ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobecovirus
''Nobecovirus'' is a subgenus of viruses in the genus ''Betacoronavirus''. The viruses in the group were previously known as group 2d coronaviruses. Structure The viruses of this subgenus, like other Coronavirus, coronaviruses, have a lipid bilayer Viral envelope, envelope in which the coronavirus membrane protein, membrane (M), coronavirus envelope protein, envelope (E) and coronavirus spike protein, spike (S) structural proteins are anchored. See also *''Embecovirus'' (group 2a) *''Sarbecovirus'' (group 2b) *''Merbecovirus'' (group 2c) References Betacoronaviruses Virus subgenera {{virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Embecovirus
''Embecovirus'' is a subgenus of coronaviruses in the genus ''Betacoronavirus''. The viruses in this subgenus, unlike other coronaviruses, have a hemagglutinin esterase (HE) gene. The viruses in the subgenus were previously known as group 2a coronaviruses. Structure The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored. Unlike other coronaviruses, viruses in this subgenus also have an additional shorter spike-like structural protein called hemagglutinin esterase (HE). Recombination Genetic recombination can occur when two or more viral genomes are present in the same host cell. The dromedary camel beta-coronavirus (Beta-CoV HKU23) exhibits genetic diversity in the African camel population.Diversity of Dromedary Camel Coronavirus HKU23 in African Camels Revealed Multiple Recombination Events among Closely Related Betacoronaviruses of the Subgenus Embecoviru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tylonycteris Bat Coronavirus HKU4
''Tylonycteris bat coronavirus HKU4'' (''Bat-CoV HKU4'') is an enveloped, positive-sense single-stranded RNA virus mammalian Group 2 ''Betacoronavirus'' that has been found to be genetically related to the ''Middle East respiratory syndrome-related coronavirus'' (''MERS-CoV'') that is responsible for the 2012 Middle East respiratory syndrome coronavirus outbreak in Saudi Arabia, Jordan, United Arab Emirates, the United Kingdom, France, and Italy. Transmission The exact means of transmission to humans is not yet well known. However, it has been demonstrated that betaCoV's including HKU4 have the propensity to recombine and cause interspecies transmission. However, this is not seen in Group C betaCov's to which MERS-CoV is most closely related. See also * Severe acute respiratory syndrome (SARS) * ''Tylonycteris'' * ''Pipistrellus'' * ''Human coronavirus HKU1'' * Human coronavirus OC43 * ''Pipistrellus bat coronavirus HKU5'' * RNA virus * Positive/negative-sense * London1 novel C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coronavirus Spike Protein
Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion. The distinctive appearance of these spikes when visualized using negative stain transmission electron microscopy, "recalling the solar corona", gives the virus family its name. The function of the spike glycoprotein is to mediate viral entry into the host cell by first interacting with molecules on the exterior cell surface and then fusing the viral and cellular membranes. Spike glycoprotein is a class I fusion protein that contains two regions, known as S1 and S2, responsible for these two functions. The S1 region contains the receptor-binding domain that binds to receptors on the cell surface. Coronaviruses use a very diverse range of receptors; SARS-CoV (which causes SARS) an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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