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MasSpec Pen
The MasSpec Pen, or the precìso MasSpec Pen System, is a mass spectrometry (MS) based cancer detection and diagnosis system that can be used for ''ex vivo'' and ''in vivo'' tissue sample analysis. The system collects biological molecules from a tissue sample surface via a solid-liquid extraction mechanism and transports the molecules to a mass spectrometer for analysis. The composition of the extracted molecules can then be used to predict if the tissue sample analyzed contains cancerous cells using machine learning algorithms and statistical models. In early-stage clinical research, the MasSpec Pen system was able to distinguish various cancer tissues, including thyroid, breast, lung, and ovarian tumor tissues, from their normal counterparts with an overall accuracy of 96.3%. A follow-up study in illustrating the use of the device for detection of serous ovarian carcinoma in ex vivo tissue biopsies allowed for the discrimination of normal and cancerous ovarian samples with a clini ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mass Spectrometry
Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used in many different fields and is applied to pure samples as well as complex mixtures. A mass spectrum is a type of plot of the ion signal as a function of the mass-to-charge ratio. These spectra are used to determine the elemental or isotopic signature of a sample, the masses of particles and of molecules, and to elucidate the chemical identity or structure of molecules and other chemical compounds. In a typical MS procedure, a sample, which may be solid, liquid, or gaseous, is ionized, for example by bombarding it with a beam of electrons. This may cause some of the sample's molecules to break up into positively charged fragments or simply become positively charged without fragmenting. These ions (fragments) are then separated accordin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Livia S
Livia Drusilla (30 January 59 BC – 28 September AD 29) was a Roman empress from 27 BC to AD 14 as the wife of Emperor Augustus Caesar. She was known as Julia Augusta after her formal adoption Adoption is a process whereby a person assumes the parenting of another, usually a child, from that person's biological or legal parent or parents. Legal adoptions permanently transfer all rights and responsibilities, along with filiation, from ... into the Julia gens, Julian family in AD 14. Livia was the daughter of Roman Senator Marcus Livius Drusus Claudianus and his wife Alfidia. She married Tiberius Claudius Nero (father of Tiberius Caesar), Tiberius Claudius Nero around 43 BC, and they had two sons, Tiberius and Nero Claudius Drusus, Drusus. In 38 BC, she divorced Tiberius Claudius Nero and married the political leader Octavian. The Senate granted Octavian the title ''Augustus (honorific), Augustus'' in 27 BC, effectively making him emperor. Livia then became the Roman empress ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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