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Mary Bartlett Bunge
Mary Elizabeth Bartlett Bunge (April 3, 1931 – February 17, 2024) was an American neuroscientist who researched a cure for paralysis at the University of Miami, where she was a professor of cell biology. Early life Mary Bartlett was born on April 3, 1931, in New Haven, Connecticut, to George Chapman Bartlett and Margaret Elizabeth (Reynolds) Bartlett. Her father built and renovated houses, including the house in which she grew up, whereas her mother, a descendant of painter Sir Joshua Reynolds, worked as a painter and decorator. Neither of her parents had a college education, and her father thought that a college education was useless for women. Their careers were filled with an artistic expression that Mary found appealing. After her grandmother taught her how to sew, she expressed herself through art and fashion by designing and making all of her own clothes with the ultimate dream to be a fashion designer in New York City. She strongly considered a career in fashion ...
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New Haven, Connecticut
New Haven is a city in the U.S. state of Connecticut. It is located on New Haven Harbor on the northern shore of Long Island Sound in New Haven County, Connecticut and is part of the New York City metropolitan area. With a population of 134,023 as determined by the 2020 U.S. census, New Haven is the third largest city in Connecticut after Bridgeport and Stamford and the principal municipality of Greater New Haven, which had a total 2020 population of 864,835. New Haven was one of the first planned cities in the U.S. A year after its founding by English Puritans in 1638, eight streets were laid out in a four-by-four grid, creating the "Nine Square Plan". The central common block is the New Haven Green, a square at the center of Downtown New Haven. The Green is now a National Historic Landmark, and the "Nine Square Plan" is recognized by the American Planning Association as a National Planning Landmark. New Haven is the home of Yale University, New Haven's biggest taxpayer ...
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Laboratory Technician
A laboratory technician is a person who works in a laboratory performing analytical or experimental procedures, maintaining laboratory equipment and assisting scientists with their work. According to the Oxford English Dictionary, the first use of the term laboratory technician was in 1896:It 'sc.'' a therapeutic propertyis now totally abandoned by the advanced laboratory technicians.The term is now widely accepted. Laboratory technicians are found in a wide range of scientific fields, including forensic science, pathology, chemistry, biomedical science and physics. More junior employees may be known as laboratory assistants, with more senior staff referred to as laboratory technical officers. Laboratory technicians may hold a range of formal academic qualifications, such as associate degrees, often obtained through vocational education Vocational education is education that prepares people to work as a technician or to take up employment in a skilled craft or trade as a t ...
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Tenure-track
Tenure is a category of academic appointment existing in some countries. A tenured post is an indefinite academic appointment that can be terminated only for cause or under extraordinary circumstances, such as financial exigency or program discontinuation. Tenure is a means of defending the principle of academic freedom, which holds that it is beneficial for society in the long run if scholars are free to hold and examine a variety of views. By country United States and Canada Under the tenure systems adopted by many universities and colleges in the United States and Canada, some faculty positions have tenure and some do not. Typical systems (such as the widely adopted "1940 Statement of Principles on Academic Freedom and Tenure" of the American Association of University Professors) allow only a limited period to establish a record of published research, ability to attract grant funding, academic visibility, teaching excellence, and administrative or community service. They ...
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Washington University School Of Medicine
Washington University School of Medicine (WUSM) is the medical school of Washington University in St. Louis in St. Louis, Missouri. Founded in 1891, the School of Medicine has 1,260 students, 604 of which are pursuing a medical degree with or without a combined Doctor of Philosophy or other advanced degree. It also offers doctorate degrees in biomedical research through the Division of Biology and Biological Sciences. The School has developed large physical therapy (273 students) and occupational therapy (233 students) programs, as well as the Program in Audiology and Communication Sciences (100 students) which includes a Doctor of Audiology (Au.D.) degree and a Master of Science in Deaf Education (M.S.D.E.) degree. There are 1,772 faculty, 1,022 residents, and 765 fellows. The clinical service is provided by Washington University Physicians, a comprehensive medical and surgical practice providing treatment in more than 75 medical specialties. Washington University Physicians ...
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Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, Columbia is the oldest institution of higher education in New York and the fifth-oldest institution of higher learning in the United States. It is one of nine colonial colleges founded prior to the Declaration of Independence. It is a member of the Ivy League. Columbia is ranked among the top universities in the world. Columbia was established by royal charter under George II of Great Britain. It was renamed Columbia College in 1784 following the American Revolution, and in 1787 was placed under a private board of trustees headed by former students Alexander Hamilton and John Jay. In 1896, the campus was moved to its current location in Morningside Heights and renamed Columbia University. Columbia scientists and scholars have ...
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Hans Ris
Hans Ris (June 15, 1914 – November 19, 2004) was an American cytologist and pioneer electron microscopy, electron microscopist. His studies of chromosome structure revealed the importance of non-histone proteins, and along with evolutionary biologist Lynn Margulis, he was one of the first to recognize that blue-green algae were a special type of bacteria. He coined the term wikt:genophore, genophore for prokaryote DNA to highlight its differences from the eukaryal chromosome. Ris was a founding member of the American Society for Cell Biology and received the Distinguished Scientist Award by the Microscopy Society of America in 1983. Biography Hans Ris was born in Bern, Switzerland on 15 June 1914, where he also grew up. Inspired by the works of the French entomologist Jean Henri Fabre, he observed the habits of ants, wasps and bees. He came to America in 1938 to work with B.H. Willier at Rochester, New York. After receiving his doctorate at Columbia University he moved to Johns ...
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Thesis
A thesis ( : theses), or dissertation (abbreviated diss.), is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings.International Standard ISO 7144: DocumentationâPresentation of theses and similar documents International Organization for Standardization, Geneva, 1986. In some contexts, the word "thesis" or a cognate is used for part of a bachelor's or master's course, while "dissertation" is normally applied to a doctorate. This is the typical arrangement in American English. In other contexts, such as within most institutions of the United Kingdom and Republic of Ireland, the reverse is true. The term graduate thesis is sometimes used to refer to both master's theses and doctoral dissertations. The required complexity or quality of research of a thesis or dissertation can vary by country, university, or program, and the required minimum study period may thus vary significantly in d ...
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Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow. Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it. Vitamin B12 is the most chemically complex of all vitamins, and for humans, the only vitamin that must be sourced from animal-derived foods or from supplements. Only some archaea and bacteria can synthesize vitamin B12. Most people in developed countries get enough B12 from the consumption of meat or foods with animal sources. Foods containing vitamin B12 include meat, clams, liver, fish, poultry, eggs, and dairy products. Many breakfast cereals are ...
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Pernicious Anemia
Pernicious anemia is a type of vitamin B12 deficiency anemia, a disease in which not enough red blood cells are produced due to the malabsorption of vitamin B12. Malabsorption in pernicious anemia results from the lack or loss of intrinsic factor needed for the absorption of vitamin B12. Anemia is defined as a condition in which the blood has a lower than normal amount of red blood cells or hemoglobin. There may be larger red blood cells than normal but they are not always present. The most common initial symptoms are tiredness, and weakness. Other signs and symptoms of anemia include breathlessness, dizziness, a sore red tongue, lightheadedness, headaches, poor ability to exercise, cold hands and feet, low blood pressure, pale or yellow skin, chest pain, and an irregular heartbeat. The digestive tract may also be disturbed giving symptoms that can include nausea and vomiting, heartburn, upset stomach and loss of appetite. Pernicious anemia can cause osteoporosis and may ...
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Gastric Juices
Gastric acid, gastric juice, or stomach acid is a digestive fluid formed within the stomach lining. With a pH between 1 and 3, gastric acid plays a key role in digestion of proteins by activating digestive enzymes, which together break down the long chains of amino acids of proteins. Gastric acid is regulated in feedback systems to increase production when needed, such as after a meal. Other cells in the stomach produce bicarbonate, a base, to buffer the fluid, ensuring a regulated pH. These cells also produce mucus – a viscous barrier to prevent gastric acid from damaging the stomach. The pancreas further produces large amounts of bicarbonate and secretes bicarbonate through the pancreatic duct to the duodenum to neutralize gastric acid passing into the digestive tract. The active components of gastric acid are protons and chloride. Often simplistically described as hydrochloric acid, these species are produced by parietal cells in the gastric glands in the stomach ...
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Intrinsic Factor
Intrinsic factor (IF), cobalamin binding intrinsic factor, also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells (in humans) or chief cells (in rodents) of the stomach. It is necessary for the absorption of vitamin B12 later on in the distal ileum of the small intestine. In humans, the gastric intrinsic factor protein is encoded by the ''CBLIF'' gene. Haptocorrin ( transcobalamin I) is another glycoprotein secreted by the salivary glands which binds to vitamin B12. Vitamin B12 is acid-sensitive and in binding to haptocorrin it can safely pass through the acidic stomach to the duodenum. In the less acidic environment of the small intestine, pancreatic enzymes digest the glycoprotein carrier and vitamin B12 can then bind to intrinsic factor. This new complex is then absorbed by the epithelial cells (enterocytes) of the ileum. Inside the cells, vitamin B12 dissociates once again and binds to another protein, transcobalamin II; the new compl ...
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University Of Wisconsin Medical School
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university ...
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