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Marjorie Roloff Stetten
Marjorie Roloff Stetten (née Roloff; 1915 − May 19, 1983) was an American biochemist whose carbohydrate metabolism research led to the advancements in biomedical knowledge of enzymes and biosynthesis and the discovery of AICA ribonucleotide. During her career, she was an investigator at the National Institutes of Health and a research professor of experimental medicine at Rutgers Medical School. Education Roloff was born in 1915 in New York City to Belle and George F. Roloff. Her paternal grandparents were from Germany. She graduated from Westfield High School. Roloff completed a B.S. from Douglass Residential College in 1937. She earned a Ph.D. from Columbia University in 1944. She was a member of Sigma Xi and Phi Beta Kappa. Her dissertation was titled, ''The metabolism of l(-)-pioIihe studied with the aid of deuterium and isotopic nitrogen''. Rudolph Schoenheimer was Stetten's doctoral advisor. Career Stetten held positions at Columbia University and Harvard ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York City
New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the List of United States cities by population density, most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York (state), New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban area, urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous Megacity, megacities, and over 58 million people live within of the city. New York City is a global city, global Culture of New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute Of Arthritis And Musculoskeletal And Skin Diseases
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is one of the institutes and centers that make up the National Institutes of Health, an agency of the United States Department of Health and Human Services (HHS). NIH is the primary federal agency that conducts and supports basic, clinical and translational medical research. The institute investigates the prevention, diagnosis, causes, treatments and cures for both common and rare diseases. Mission NIAMS' mission is to support the research of arthritis, musculoskeletal and skin diseases.The institute also disseminates information on research progress in these diseases. NIAMS supports and conducts basic, clinical, translational and epidemiologic research and research training at universities and medical centers. The institute also conducts and supports basic research on the normal structure and function of bones, joints, muscles, and skin. Basic research involves a wide variety of scientific disc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American People Of German Descent
German Americans (german: Deutschamerikaner, ) are Americans who have full or partial German ancestry. With an estimated size of approximately 43 million in 2019, German Americans are the largest of the self-reported ancestry groups by the United States Census Bureau in its American Community Survey. German Americans account for about one third of the total population of people of German ancestry in the world. Very few of the German states had colonies in the new world. In the 1670s, the first significant groups of German immigrants arrived in the British colonies, settling primarily in Pennsylvania, New York and Virginia. The Mississippi Company of France moved thousands of Germans from Europe to Louisiana and to the German Coast, Orleans Territory between 1718 and 1750. Immigration ramped up sharply during the 19th century. There is a "German belt" that extends all the way across the United States, from eastern Pennsylvania to the Oregon coast. Pennsylvania, with 3.5 milli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientists From New York City
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have advanced degrees in an area of science and pursue careers in various sectors of the economy such as academia, industry, government, and nonprofit environments.'''' History The roles ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Women Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1983 Deaths
The year 1983 saw both the official beginning of the Internet and the first mobile cellular telephone call. Events January * January 1 – The migration of the ARPANET to TCP/IP is officially completed (this is considered to be the beginning of the true Internet). * January 24 – Twenty-five members of the Red Brigades are sentenced to life imprisonment for the 1978 murder of Italian politician Aldo Moro. * January 25 ** High-ranking Nazi war criminal Klaus Barbie is arrested in Bolivia. ** IRAS is launched from Vandenberg AFB, to conduct the world's first all-sky infrared survey from space. February * February 2 – Giovanni Vigliotto goes on trial on charges of polygamy involving 105 women. * February 3 – Prime Minister of Australia Malcolm Fraser is granted a double dissolution of both houses of parliament, for elections on March 5, 1983. As Fraser is being granted the dissolution, Bill Hayden resigns as leader of the Australian Labor Party, and in the subsequ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tudor Period
The Tudor period occurred between 1485 and 1603 in History of England, England and Wales and includes the Elizabethan period during the reign of Elizabeth I until 1603. The Tudor period coincides with the dynasty of the House of Tudor in England that began with the reign of Henry VII of England, Henry VII (b. 1457, r. 14851509). Historian John Guy (historian), John Guy (1988) argued that "England was economically healthier, more expansive, and more optimistic under the Tudors" than at any time since the Roman occupation. Population and economy Following the Black Death and the agricultural depression of the late 15th century, the population began to increase. In 1520, it was around 2.3 million. By 1600 it had doubled to 4 million. The growing population stimulated economic growth, accelerated the commercialisation of agriculture, increased the production and export of wool, encouraged trade, and promoted the growth of London. The high wages and abundance of available land seen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elizabethan Era
The Elizabethan era is the epoch in the Tudor period of the history of England during the reign of Queen Elizabeth I (1558–1603). Historians often depict it as the golden age in English history. The symbol of Britannia (a female personification of Great Britain) was first used in 1572, and often thereafter, to mark the Elizabethan age as a renaissance that inspired national pride through classical ideals, international expansion, and naval triumph over Spain. This "golden age" represented the apogee of the English Renaissance and saw the flowering of poetry, music and literature. The era is most famous for its theatre, as William Shakespeare and many others composed plays that broke free of England's past style of theatre. It was an age of exploration and expansion abroad, while back at home, the Protestant Reformation became more acceptable to the people, most certainly after the Spanish Armada was repelled. It was also the end of the period when England was a separate r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Biological Chemists
The American Society for Biochemistry and Molecular Biology (ASBMB) is a learned society that was founded on December 26, 1906, at a meeting organized by John Jacob Abel (Johns Hopkins University). The roots of the society were in the American Physiological Society, which had been formed some 20 years earlier. ASBMB is the US member of the International Union of Biochemistry and Molecular Biology. The ASBMB was originally called the American Society of Biological Chemists, before obtaining its current name in 1987. The society is based in Rockville, Maryland. ASBMB's mission is to advance the science of biochemistry and molecular biology through publication of scientific and educational journals, the organization of scientific meetings, advocacy for funding of basic research and education, support of science education at all levels, and by promoting the diversity of individuals entering the scientific workforce. The organization currently has over 12,000 members. Publications ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marine Biological Laboratory
The Marine Biological Laboratory (MBL) is an international center for research and education in biological and environmental science. Founded in Woods Hole, Massachusetts, in 1888, the MBL is a private, nonprofit institution that was independent for most of its history, but became officially affiliated with the University of Chicago on July 1, 2013. It also collaborates with numerous other institutions. As of 2022, 60 Nobel Prize winners have been affiliated with MBL as students, faculty members or researchers. In addition since 1960, there have been, 137 Howard Hughes Medical Institute investigators, early career scientists, international researchers, and professors; 306 members of the National Academy of Sciences; and 236 Members of the American Academy of Arts and Sciences who have been affiliated with the lab. History 19th century The Marine Biological Laboratory grew from the vision of several Bostonians and Spencer Fullerton Baird, the United States' first Fish Commiss ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucose 6-phosphatase
The enzyme glucose 6-phosphatase (EC 3.1.3.9, G6Pase; systematic name D-glucose-6-phosphate phosphohydrolase) catalyzes the hydrolysis of glucose 6-phosphate, resulting in the creation of a phosphate group and free glucose: : D-glucose 6-phosphate + H2O = D-glucose + phosphate Glucose is then exported from the cell via glucose transporter membrane proteins. This catalysis completes the final step in gluconeogenesis and therefore plays a key role in the homeostatic regulation of blood glucose levels. Glucose 6-phosphatase is a complex of multiple component proteins, including transporters for G6P, glucose, and phosphate. The main phosphatase function is performed by the glucose 6-phosphatase catalytic subunit. In humans, there are three isozymes of the catalytic subunit: glucose 6-phosphatase-α, encoded by G6PC; IGRP, encoded by G6PC2; and glucose 6-phosphatase-β, encoded by G6PC3. Glucose 6-phosphatase-α and glucose 6-phosphatase-β are both functional phosphohydrola ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
