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Marjorie G. Horning
Marjorie Janice Groothuis Horning (August 23, 1917 – June 11, 2020) was an American biochemist and pharmacologist. She was considered to be a pioneer of chromatography for her work in developing new techniques and applying them to the study of drug metabolism. She demonstrated that drugs and their metabolites can be transferred from a pregnant woman to her developing child, and later through breast milk, from a mother to a baby. Horning's work made possible the prevention of birth defects, as doctors began to warn of the dangers of drugs, alcohol, and smoking during pregnancy. Early life and education Marjorie Janice Groothuis was born in August 1917 in Detroit, Michigan, to Nina Jane Potter and Herman Groothuis. She studied at Goucher College in Baltimore, Maryland, graduating with a Bachelor of Arts in 1938. She then attended the University of Michigan, graduating with a Master of Science in 1940 and a Doctor of Philosophy in 1943. She worked as a research assistant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Detroit
Detroit ( , ; , ) is the largest city in the U.S. state of Michigan. It is also the largest U.S. city on the United States–Canada border, and the seat of government of Wayne County. The City of Detroit had a population of 639,111 at the 2020 census, making it the 27th-most populous city in the United States. The metropolitan area, known as Metro Detroit, is home to 4.3 million people, making it the second-largest in the Midwest after the Chicago metropolitan area, and the 14th-largest in the United States. Regarded as a major cultural center, Detroit is known for its contributions to music, art, architecture and design, in addition to its historical automotive background. ''Time'' named Detroit as one of the fifty World's Greatest Places of 2022 to explore. Detroit is a major port on the Detroit River, one of the four major straits that connect the Great Lakes system to the Saint Lawrence Seaway. The City of Detroit anchors the second-largest regional economy in t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Michigan Health System
Michigan Medicine (University of Michigan Health System or UMHS before 2017) is the wholly owned academic medical center of the University of Michigan, a public research university in Ann Arbor, Michigan. Michigan Medicine includes the University of Michigan Medical School, with its faculty group practice and research laboratories; the university's affiliated hospitals and health centers, including the University of Michigan Hospital, C.S. Mott Children's Hospital, Von Voigtlander Women's Hospital, and approximately 40 health centers and home care services across southeast Michigan; the clinical programs of the University of Michigan School of Nursing; and the activities of the Michigan Health Corporation, through which U-M partners with other medical centers and hospitals to provide specialized care throughout Michigan. History In 1869 the University of Michigan opened the first hospital in the country owned and operated by a university, in a house in Ann Arbor originally ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Pharmacology And Experimental Therapeutics
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University (also the founder of the American Society for Biochemistry and Molecular Biology), with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis. Publications The society publishes three research journals and a review journal: the ''Journal of Pharmacology and Experimental Therapeutics'', ''Drug Metabolism and Disposition'', ''Molecular Pharmacology'', and ''Pharmacological Reviews'' Starting in 2012 these publications are only offered online. The society copublishes a who ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trends In Pharmacological Sciences
A fad or trend is any form of collective behavior that develops within a culture, a generation or social group in which a group of people enthusiastically follow an impulse for a short period. Fads are objects or behaviors that achieve short-lived popularity but fade away. Fads are often seen as sudden, quick-spreading, and short-lived. Fads include diets, clothing, hairstyles, toys, and more. Some popular fads throughout history are toys such as yo-yos, hula hoops, and fad dances such as the Macarena, floss and the twist. Similar to habits or customs but less durable, fads often result from an activity or behavior being perceived as emotionally popular or exciting within a peer group, or being deemed " cool" as often promoted by social networks.Kornblum (2007), p. 213. A fad is said to "catch on" when the number of people adopting it begins to increase to the point of being noteworthy. Fads often fade quickly when the perception of novelty is gone. Overview The specific nat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Chromatography B
The ''Journal of Chromatography B'' is a Peer review, peer-reviewed scientific journal publishing research papers in analytical chemistry, with a focus on chromatography techniques and methods in the biological and life sciences. According to the ''Journal Citation Reports'', 'Journal of Chromatography B'' has a 2020 impact factor of 3.205, ranking it 36th out of 83 in the category of Chemistry, Analytical. See also * Journal of Chromatography A References Publications established in 1958 Elsevier academic journals Chemistry journals {{chemistry-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxicology And Applied Pharmacology
''Toxicology and Applied Pharmacology'' is a scientific journal for original research pertaining to action of chemicals, drugs, or natural products to animals or humans. The journal covers mechanistic approaches to physiological, biochemical, cellular, or molecular understanding of toxicologic/pathologic lesions and to methods used to describe these responses. Indexing The journal is included in the Index Medicus and in MEDLINE. According to the ''Journal Citation Reports'', ''Toxicology and Applied Pharmacology'' has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 4.219, ranking it 29 out of 93 in the category ''Toxicology''. References External links Elsevier {{DEFAULTSORT:Toxicology And Applied Pharmacology Monthly journals Elsevier academic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analytical Chemistry (journal)
''Analytical Chemistry'' is a biweekly peer-reviewed scientific journal published since 1929 by the American Chemical Society. Articles address general principles of chemical measurement science and novel analytical methodologies. Topics commonly include chemical reactions and selectivity, chemometrics and data processing, electrochemistry, elemental and molecular characterization, imaging, instrumentation, mass spectrometry, microscale and nanoscale systems, -omics, sensing, separations, spectroscopy, and surface analysis. It is abstracted and indexed in Chemical Abstracts Service, CAB International, EBSCOhost, ProQuest, PubMed, Scopus, and the Science Citation Index Expanded. According to the ''Journal Citation Reports'', it has a 2020 impact factor of 6.986 . The editor-in-chief is Jonathan V. Sweedler (University of Illinois). See also * List of chemistry journals References External links * {{DEFAULTSORT:Analytical Chemistry (Journal) Analytical Chemistry Analyti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Metabolism And Disposition
''Drug Metabolism and Disposition'' is a peer-reviewed scientific journal covering the fields of pharmacology and toxicology. It was established in 1973 and is published monthly by the American Society for Pharmacology and Experimental Therapeutics. The journal publishes articles on ''in vitro'' and ''in vivo'' studies of the metabolism, transport, and disposition of drugs and environmental chemicals, including the expression of drug-metabolizing enzymes and their regulation. , the editor-in-chief is XinXin Ding. All issues are available online as PDFs, with text versions additionally available from 1997. Content from 1997 is available freely 12 months after publication. History ''Drug Metabolism and Disposition'' was established in 1973 by Kenneth C. Leibman. The initial frequency was bimonthly (six annual issues); it increased to monthly in 1995. The journal was published on behalf of the society by Williams & Wilkins until the end of 1996. Abstracting and indexing According t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Houston
The University of Houston (UH) is a Public university, public research university in Houston, Texas. Founded in 1927, UH is a member of the University of Houston System and the List of universities in Texas by enrollment, university in Texas with over 47,000 students. Its campus, which is primarily in southeast Houston, spans , with the inclusion of its Sugar Land and Katy sites. The university is Carnegie Classification of Institutions of Higher Education, classified as an "R1: Doctoral Universities – Very high research activity." The university offers more than 276 degree programs through its 16 academic colleges and schools and an interdisciplinary Honors College - including programs leading to professional degrees in architecture, law, optometry, medicine and pharmacy. The institution spends $203 million annually in research, and operates more than 35 research centers and institutes on campus. Interdisciplinary research includes superconductivity, space commercializatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Houston, Texas
Houston (; ) is the most populous city in Texas, the most populous city in the Southern United States, the fourth-most populous city in the United States, and the sixth-most populous city in North America, with a population of 2,304,580 in 2020. Located in Southeast Texas near Galveston Bay and the Gulf of Mexico, it is the seat and largest city of Harris County and the principal city of the Greater Houston metropolitan area, which is the fifth-most populous metropolitan statistical area in the United States and the second-most populous in Texas after Dallas–Fort Worth. Houston is the southeast anchor of the greater megaregion known as the Texas Triangle. Comprising a land area of , Houston is the ninth-most expansive city in the United States (including consolidated city-counties). It is the largest city in the United States by total area whose government is not consolidated with a county, parish, or borough. Though primarily in Harris County, small portions of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Heart, Lung, And Blood Institute
The National Heart, Lung, and Blood Institute (NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States. It is tasked with allocating about $3.6 billion in FY 2020 in tax revenue to advancing the understanding of the following issues: development and progression of disease, diagnosis of disease, treatment of disease, disease prevention, reduction of health care disparities within the American population, and advancing the effectiveness of the US medical system. NHLBI's Director is Gary H. Gibbons (2012–present). Operation In 1948, the National Heart Act established the National Heart Institute and the National Advisory Heart Council. The intramural research program was established a year later in 1949. In 1969, the National Heart Institute was renamed the National Heart and Lung Institute, and the scope of the institute was expanded. In 1976, it was given its current name, the National Heart, Lung, and Blood Insti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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