|
Marcus Pembrey
Marcus Edred Pembrey FMedSci (born 20 April 1943) is a British clinical geneticist with a research interest in non-Mendelian inheritance in humans. He is Emeritus Professor of Paediatric Genetics at UCL Great Ormond Street Institute of Child Health and Visiting Professor of Paediatric Genetics, University of Bristol. He featured in a 2005 'Horizon' program on BBC television called 'the Ghost in Your Gene Early life and education Born into a medical family, Marcus Pembrey spent his childhood in Hurstpierpoint, Sussex, where his father was a General Practitioner. The rural setting and his aunts’ farm encouraged an interest in natural history. Educated at Hurstpierpoint College, he went to Guy's Hospital Medical School, London in 1960; with postgraduate research training at the Nuffield Unit of Medical Genetics, University of Liverpool 1969-71. Career and research After further clinical training at Guy's Hospital, in 1979 he was appointed head of the new Mothercare Unit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British People
British people or Britons, also known colloquially as Brits, are the citizens of the United Kingdom of Great Britain and Northern Ireland, the British Overseas Territories, and the Crown dependencies.: British nationality law governs modern British citizenship and nationality, which can be acquired, for instance, by descent from British nationals. When used in a historical context, "British" or "Britons" can refer to the Ancient Britons, the indigenous inhabitants of Great Britain and Brittany, whose surviving members are the modern Welsh people, Cornish people, and Bretons. It also refers to citizens of the former British Empire, who settled in the country prior to 1973, and hold neither UK citizenship nor nationality. Though early assertions of being British date from the Late Middle Ages, the Union of the Crowns in 1603 and the creation of the Kingdom of Great Britain in 1707 triggered a sense of British national identity.. The notion of Britishness and a shared Brit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Geneticist
Medical genetics is the branch tics in that human genetics is a field of scientific research that may or may not apply to medicine, while medical genetics refers to the application of genetics to medical care. For example, research on the causes and inheritance of genetic disorders would be considered within both human genetics and medical genetics, while the diagnosis, management, and counselling people with genetic disorders would be considered part of medical genetics. In contrast, the study of typically non-medical phenotypes such as the genetics of eye color would be considered part of human genetics, but not necessarily relevant to medical genetics (except in situations such as albinism). ''Genetic medicine'' is a newer term for medical genetics and incorporates areas such as gene therapy, personalized medicine, and the rapidly emerging new medical specialty, predictive medicine. Scope Medical genetics encompasses many different areas, including clinical practice of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-Mendelian Inheritance
Non-Mendelian inheritance is any pattern in which traits do not segregate in accordance with Mendel's laws. These laws describe the inheritance of traits linked to single genes on chromosomes in the nucleus. In Mendelian inheritance, each parent contributes one of two possible alleles for a trait. If the genotypes of both parents in a genetic cross are known, Mendel's laws can be used to determine the distribution of phenotypes expected for the population of offspring. There are several situations in which the proportions of phenotypes observed in the progeny do not match the predicted values. Non-Mendelian inheritance plays a role in several disease which affected the processes. Types Incomplete dominance In cases of intermediate inheritance due to incomplete dominance, the principle of dominance discovered by Mendel does not apply. Nevertheless, the principle of uniformity works, as all offspring in the F1-generation have the same genotype and same phenotype. Mendel's prin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Horizon (BBC TV Series)
''Horizon'' is an ongoing and long-running British documentary television series on BBC Two that covers science and philosophy. History The programme was first broadcast on 2 May 1964 with "The World of Buckminster Fuller" which explored the theories and structures of inventor Richard Buckminster Fuller and included the ''Horizon'' mission statement: "The aim of ''Horizon'' is to provide a platform from which some of the world's greatest scientists and philosophers can communicate their curiosity, observations and reflections, and infuse into our common knowledge their changing views of the universe". ''Horizon'' continues to be broadcast on BBC Two, and in 2009 added a series of films based on the rich ''Horizon'' archive called ''Horizon Guides'' on BBC Four. In December 2016, it was announced that ''Horizon'' will no longer be made exclusively by the BBC's in-house production division, BBC Studios, and the BBC invited independent production companies to pitch to make episodes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hurstpierpoint College
(''Blessed are the pure in heart'') , established = , closed = , type = Public SchoolIndependent School , religious_affiliation = Church of England , president = , head_label = Headmaster , head = Dominic Mott , r_head_label = , r_head = , chair_label = Chairman of Governors , chair = Tony Jarvis , founder = Canon Nathaniel Woodard , specialist = , address = College Lane , city = Hurstpierpoint , county = West Sussex , country = England , postcode = BN6 9JS , local_authority = West Sussex , ofsted = , dfeno = 938/6206 , staff = , enrolment = c.1,337 , gender = Mixed , lower_age = 4 , upper_age = 18 , houses = 13 , colours = Red and White , publication = , free_label_1 = Former pupils , free_1 = Old Johnians , free_label_2 Alumni Website, free_2 www.theojclub.com, free_label_3 = Affiliation , free_ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Liverpool
, mottoeng = These days of peace foster learning , established = 1881 – University College Liverpool1884 – affiliated to the federal Victoria Universityhttp://www.legislation.gov.uk/ukla/2004/4 University of Manchester Act 2004. legislation.gov.uk (4 July 2011). Retrieved on 14 September 2011.1903 – royal charter , type = Public , endowment = £190.2 million (2020) , budget = £597.4 million (2020–21) , city = Liverpool , country = England , campus = Urban , coor = , chancellor = Colm Tóibín , vice_chancellor = Dame Janet Beer , head_label = Visitor , head = The Lord President of the Council '' ex officio'' , students = () , undergrad = () , postgrad = () , colours = The University , affiliations = Russell Group, EUA, N8 Group, NWUA, AACSB, AMBA, EQUIS, EASN, Universities UK , website = , logo = Universit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ALSPAC
The Avon Longitudinal Study of Parents and Children (ALSPAC), also known as Children of the 90s and formerly the Avon Longitudinal Study of Pregnancy and Childhood, is a cohort study of children born in the former county of Avon, England during 1991 and 1992.http://www.bristol.ac.uk/alspac/ ALSPAC website, accessed 15 October 2014 It is used by researchers in health, education and other social science disciplines. The study is hosted at the University of Bristol and was initially led by Jean Golding, then George Davey Smith. Currently the Principal Investigator for the study is Prof Nic Timpson. The initial recruits were 15,247 pregnant women with estimated dates of delivery between April 1991 and December 1992. Since then the fathers, siblings and children of the participants have also begun to be studied and the study has launched Children of the Children of the 90s as a new generation is born. It is one of a family of similar studies that were set up at around the same time ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward J
Edward is an English given name. It is derived from the Anglo-Saxon name ''Ēadweard'', composed of the elements '' ēad'' "wealth, fortune; prosperous" and '' weard'' "guardian, protector”. History The name Edward was very popular in Anglo-Saxon England, but the rule of the Norman and Plantagenet dynasties had effectively ended its use amongst the upper classes. The popularity of the name was revived when Henry III named his firstborn son, the future Edward I, as part of his efforts to promote a cult around Edward the Confessor, for whom Henry had a deep admiration. Variant forms The name has been adopted in the Iberian peninsula since the 15th century, due to Edward, King of Portugal, whose mother was English. The Spanish/Portuguese forms of the name are Eduardo and Duarte. Other variant forms include French Édouard, Italian Edoardo and Odoardo, German, Dutch, Czech and Romanian Eduard and Scandinavian Edvard. Short forms include Ed, Eddy, Eddie, Ted, Teddy and Ned ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marion J
Marion may refer to: People *Marion (given name) *Marion (surname) *Marion Silva Fernandes, Brazilian footballer known simply as "Marion" *Marion (singer), Filipino singer-songwriter and pianist Marion Aunor (born 1992) Places Antarctica * Marion Nunataks, Charcot Island Australia * City of Marion, a local government area in South Australia * Marion, South Australia, a suburb of Adelaide Cyprus * Marion, Cyprus, an ancient city-state South Africa *Marion Island, one of the Prince Edward Islands United States * Marion, Alabama * Marion, Arkansas * Marion, Connecticut ** Marion Historic District (Cheshire and Southington, Connecticut) * Marion, Georgia * Marion, Illinois * Marion, Indiana, Grant County * Marion, Shelby County, Indiana * Marion, Iowa * Marion, Kansas ** Marion County Lake ** Marion Reservoir * Marion, Kentucky * Marion, Louisiana * Marion, Massachusetts * Marion Station, Maryland, often referred to as just "Marion" * Marion, Michigan * Marion, Minnesota * Marion ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eva Jablonka
Eva Jablonka ( he, חווה יבלונקה) (born 1952) is an Israeli evolutionary theorist and geneticist, known especially for her interest in epigenetic inheritance. Born in 1952 in Poland, she emigrated to Israel in 1957. She is a professor at the Cohn Institute for the History of Philosophy of Science and Ideas at Tel Aviv University. In 1981 she was awarded the Landau prize of Israel for outstanding Master of Science (M.Sc.) work and in 1988, the Marcus prize for outstanding Ph.D. work. She is a proponent of academic freedom, recognising that on such matters, "academic and political issues cannot really be kept apart", although she is not a proponent of simplistic solutions, and shows a preference to describe her own position. Work on evolutionary themes Jablonka publishes about evolutionary themes, especially epigenetics. Her emphasis on non-genetic forms of evolution has received interest from those attempting to expand the scope of evolutionist thinking into other sphere ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neo-Lamarckism
Lamarckism, also known as Lamarckian inheritance or neo-Lamarckism, is the notion that an organism can pass on to its offspring physical characteristics that the parent organism acquired through use or disuse during its lifetime. It is also called the inheritance of acquired characteristics or more recently soft inheritance. The idea is named after the French zoologist Jean-Baptiste Lamarck (1744–1829), who incorporated the classical era theory of soft inheritance into his theory of evolution as a supplement to his concept of orthogenesis, a drive towards Evolution of biological complexity, complexity. Introductory textbooks contrast Lamarckism with Charles Darwin's theory of evolution by natural selection. However, Darwin's book ''On the Origin of Species'' gave credence to the idea of heritable effects of use and disuse, as Lamarck had done, and his own concept of pangenesis similarly implied soft inheritance. Many researchers from the 1860s onwards attempted to find evidence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
