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Mallinckrodt Pharmaceuticals
Mallinckrodt Pharmaceuticals is an American-Irish domiciled manufacturer of specialty pharmaceuticals (namely, adrenocorticotropic hormone), generic drugs and imaging agents. In 2017 it generated 90% of its sales from the U.S. healthcare system. While Mallinckrodt is headquartered in Ireland for tax purposes, its operational headquarters are in the U.S. Mallinckrodt's 2013 tax inversion to Ireland drew controversy when it was shown Acthar was Medicaid's most expensive drug. Mallinckrodt acquires (for repricing), manufactures, and distributes products used in diagnostic procedures and in the treatment of pain and related conditions. This includes the acquisition, manufacture, and distribution of specialty pharmaceuticals, active pharmaceutical ingredients, contrast products, and radiopharmaceuticals. The company employed 5,500 and had net sales of $3.2 billion in 2017; of which $2.9 billion was from the U.S. healthcare system. The company has been implicated as a major contrib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contrast Medium
A contrast agent (or contrast medium) is a substance used to increase the contrast of structures or fluids within the body in medical imaging. Contrast agents absorb or alter external electromagnetism or ultrasound, which is different from radiopharmaceuticals, which emit radiation themselves. In x-rays, contrast agents enhance the radiodensity in a target tissue or structure. In MRIs, contrast agents shorten (or in some instances increase) the relaxation times of nuclei within body tissues in order to alter the contrast in the image. Contrast agents are commonly used to improve the visibility of blood vessels and the gastrointestinal tract. Several types of contrast agent are in use in medical imaging and they can roughly be classified based on the imaging modalities where they are used. Most common contrast agents work based on X-ray attenuation and magnetic resonance signal enhancement. Radiocontrast media For radiography, which is based on X-rays, iodine and barium are the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Washington University In St
Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on Washington, D.C. * George Washington George Washington (February 22, 1732, 1799) was an American military officer, statesman, and Founding Father who served as the first president of the United States from 1789 to 1797. Appointed by the Continental Congress as commander of th ... (1732–1799), the first president of the United States Washington may also refer to: Places England * Washington, Tyne and Wear, a town in the City of Sunderland metropolitan borough ** Washington Old Hall, ancestral home of the family of George Washington * Washington, West Sussex, a village and civil parish Greenland * Cape Washington, Greenland * Washington Land Philippines *New Washington, Aklan, a municipality *Washington, a barangay in Catar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyco International
Tyco International plc was a security systems company incorporated in the Republic of Ireland, with operational headquarters in Princeton, New Jersey, United States (Tyco International (US) Inc.). Tyco International was composed of two major business segments: security solutions and fire protection. On January 25, 2016, Johnson Controls announced it would merge with Tyco, and all businesses of Tyco and Johnson Controls would be combined under Tyco International plc, to be renamed as Johnson Controls International plc. The merger was completed on September 9, 2016. Timeline 1960s Founded by Arthur J. Rosenberg in 1960, Tyco, Inc. was formed as an investment and holding company with two segments: Tyco Semiconductors and The Materials Research Laboratory. In the first two years of operation, the company focused primarily on governmental research and military experiments in the private sector. In 1962, the business was incorporated in Massachusetts and refocused on high-tech ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Minerals And Chemical Corporation
IMC Global (also known as International Minerals and Chemical Corporation and Imcera) was a mining and production company, formerly listed on the S&P MidCap 400. It was founded in 1909 as International Agricultural Corporation. In 2004, IMC Global merged with Cargill, Inc.'s crop nutrition division to form The Mosaic Company, a crop nutrition company. History IMC Global was incorporated as International Agricultural Corporation on June 14, 1909 by Walderman Schmidten in the state of New York. A native German, Schmidten moved to secure entire capital in mines from his home country; he was successful in doing so with the Kaliwerke Sollstedt Gewerkschaft. Phosphate and potash production facilities were acquired in Tennessee and Florida. Capital stock of the International Agricultural Corporation was originally fixed at $15 million in July 1909, but increased to $36 million by April 1911. As World War I broke out, demand for fertilizer declined while that for sulfuric acid skyrocketed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avon Products
Avon Products, Inc. or simply known as Avon, is an American-British multinational cosmetics, skin care, fragrance and personal care company, based in London. It sells directly to the public. Avon had annual sales of $9.1 billion worldwide in 2020. It is the fourteenth-largest beauty company and, with 6.4 million representatives, is the second largest direct-selling enterprise in the world (after Amway). The company's CEO is Angela Cretu, who was appointed to the position in January 2020. In May 2019, the multinational company Natura & Co announced its intent to acquire Avon; the deal closed in January 2020. Following the merger, existing Natura shareholders held 73% of the combined company, Natura Holding S.A., with former Avon shareholders owning 27%. At merger completion, Avon became a privately held company, common stock was removed from the NYSE trading. History Avon's founder, David H. McConnell, initially sold books as a door-to-door salesman to New York homes. In Se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Environmental Protection Agency
The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it began operation on December 2, 1970, after Nixon signed an executive order. The order establishing the EPA was ratified by committee hearings in the House and Senate. The agency is led by its administrator, who is appointed by the president and approved by the Senate. The current administrator is Michael S. Regan. The EPA is not a Cabinet department, but the administrator is normally given cabinet rank. The EPA has its headquarters in Washington, D.C., regional offices for each of the agency's ten regions and 27 laboratories. The agency conducts environmental assessment, research, and education. It has the responsibility of maintaining and enforcing national standards under a variety of environmental laws, in consultation with state, tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Superfund
Superfund is a United States federal environmental remediation program established by the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). The program is administered by the United States Environmental Protection Agency, Environmental Protection Agency (EPA). The program is designed to investigate and clean up sites contaminated with hazardous substances. Sites managed under this program are referred to as "Superfund" sites. There are 40,000 federal Superfund sites across the country, and approximately 1,300 of those sites have been listed on the National Priorities List (NPL). Sites on the NPL are considered the most highly contaminated and undergo longer-term remedial investigation and remedial action (cleanups). The EPA seeks to identify parties responsible for hazardous substances released to the environment (polluters) and either compel them to clean up the sites, or it may undertake the cleanup on its own using the Superfund (a trust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coldwater Creek (Missouri River Tributary)
Coldwater Creek (also Cold Water Creek) is a 19-mile tributary of the Missouri River in north St. Louis County in the U.S. state of Missouri. It is known to be contaminated with radioactive wastes. Location The creek begins in a small spring-fed lake in Overland, then flows north through the towns of Breckenridge Hills, St. Ann and Bridgeton, before entering a culvert underneath Lambert International Airport. North of the airport, it flows northeast through the cities of Hazelwood, Berkeley, Florissant, Old Jamestown, Black Jack, and Spanish Lake. According to ''St. Louis Magazine'', "It runs past schools, golf courses, and soccer fields." The creek terminates in the Missouri River between the Lewis Bridge and the Columbia Bottom Conservation Area. History The name "Coldwater Creek" is a translation of the original French name ''Rivière de L'eau Froide''. The Spaniards called it Rio Fernando, Spanish for "Ferdinand River." The French also called it Riviere aux Bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uranium Ore
Uranium ore deposits are economically recoverable concentrations of uranium Uranium is a chemical element with the symbol U and atomic number 92. It is a silvery-grey metal in the actinide series of the periodic table. A uranium atom has 92 protons and 92 electrons, of which 6 are valence electrons. Uranium is weak ... within the Earth's crust (geology), crust. Uranium is one of the more common elements in the Earth's crust, being 40 times more common than silver and 500 times more common than gold. It can be found almost everywhere in rock, soil, rivers, and oceans. The challenge for commercial uranium extraction is to find those areas where the concentrations are adequate to form an economically viable deposit. The primary use for uranium obtained from mining is in fuel for nuclear reactors. Globally, the distribution of uranium ore deposits is widespread on all continents, with the largest deposits found in Australia, Kazakhstan, and Canada. To date, high-grade deposi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arthur Holly Compton
Arthur Holly Compton (September 10, 1892 – March 15, 1962) was an American physicist who won the Nobel Prize in Physics in 1927 for his 1923 discovery of the Compton effect, which demonstrated the particle nature of electromagnetic radiation. It was a sensational discovery at the time: the wave nature of light had been well-demonstrated, but the idea that light had both wave and particle properties was not easily accepted. He is also known for his leadership over the Metallurgical Laboratory at the University of Chicago during the Manhattan Project, and served as chancellor of Washington University in St. Louis from 1945 to 1953. In 1919, Compton was awarded one of the first two National Research Council Fellowships that allowed students to study abroad. He chose to go to the University of Cambridge's Cavendish Laboratory in England, where he studied the scattering and absorption of gamma rays. Further research along these lines led to the discovery of the Compton ef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Manhattan Project
The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project was under the direction of Major General Leslie Groves of the United States Army Corps of Engineers, U.S. Army Corps of Engineers. Nuclear physicist Robert Oppenheimer was the director of the Los Alamos Laboratory that designed the actual bombs. The Army component of the project was designated the Manhattan District as its first headquarters were in Manhattan; the placename gradually superseded the official codename, Development of Substitute Materials, for the entire project. Along the way, the project absorbed its earlier British counterpart, Tube Alloys. The Manhattan Project began modestly in 1939, but grew to employ more than 130,000 people and cost nearly US$2 billion (equivalent to about $ billion in ). Over 90 percent of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
