Malcolm VandenBurg
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Malcolm VandenBurg
Malcolm VandenBurg is a British doctor involved in drug research, sexual health, medicolegal advice and stress management. Medical career VandenBurg qualified in St Bartholomew's Hospital in 1973 with a BSc in Physiology. He lectured in medicine, as an Honorary Senior Registrar at the London Hospital and as an Honorary Lecturer in Clinical Pharmacology at St Bartholomew's Hospital VandenBurg is a Fellow of the Royal College of Physicians, the American College of Clinical Pharmacology and the Faculty of Pharmaceutical Medicine He established the London Hospital Hypertension Clinic in 1975. Research VandenBurg was director of cardiovascular research, Old Church Hospital Romford (1984–1996) and director of clinical research at Merck Sharpe & Dohme (1980–1984) In 1996 he was appointed president and chief executive officer of global research consultancy IBRD – Rostrum Inc. VandenBurg has coordinated drug development programmes for over 30 pharmaceutical products and h ...
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Drug Research
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process – from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials – to approved vaccine or drug typically takes more than a decade. New chemical entity development Broadly, the process of drug development can be divided into preclinical and clinical work. Pre-clinical New chemical entities (NCEs, also known as new molecular entities or NMEs) are compounds that emerge from the process of drug discovery. Thes ...
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Death Of Sean Rigg
Sean Rigg was a 40-year-old black British musician and music producer who had paranoid schizophrenia. He died following a cardiac arrest on 21 August 2008 while in police custody at the entrance to Brixton police station, South London, England. The case became a cause célèbre for civil rights and justice campaigners in the United Kingdom, who called for "improvement and change on a national level" regarding deaths in police custody and the police treatment of suspects with mental health issues. Events leading to death Following a deterioration in his mental health, Rigg—who lived in a hostel for people with a forensic mental health history—became uncooperative and aggressive. Five 999 calls were made over a three-hour period by the hostel staff requesting emergency police help. During the fifth call, operator Maurice Gluck insisted that Rigg was not a police priority, informed the caller to speak with her MP if she was unhappy, and terminated the call. Police eventually res ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Death Of Michael Jackson
On June 25, 2009, American singer Michael Jackson died of acute propofol and benzodiazepine intoxication at his home on North Carolwood Drive in the Holmby Hills neighborhood of Los Angeles, California. His physician, Conrad Murray, said that he found Jackson in his room not breathing and with a weak pulse; he administered cardiopulmonary resuscitation (CPR) to no avail, and security called 9-1-1 at 12:21 p.m. Pacific Daylight Time ( UTC–7). Paramedics treated Jackson at the scene, but he was pronounced dead at the Ronald Reagan UCLA Medical Center. On August 28, 2009, the Los Angeles County Department of Medical Examiner-Coroner concluded that Jackson's death was a homicide. Jackson had been administered propofol and anti-anxiety benzodiazepines lorazepam and midazolam by his doctor. Murray was California v. Murray, convicted of involuntary manslaughter in November 2011, and was released in 2013 after serving two years of his four-year prison sentence with time off for ...
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Propofol
Propofol, marketed as Diprivan, among other names, is a short-acting medication that results in a decreased level of consciousness and a lack of memory for events. Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. It is also used for status epilepticus if other medications have not worked. It is given by injection into a vein, and the maximum effect takes about two minutes to occur and typically lasts five to ten minutes. Propofol is also used for medical assistance in dying in Canada. The medication appears to be safe for use during pregnancy but has not been well studied for use in this case. It is not recommended for use during a cesarean section. It is not a pain medication, so opioids such as morphine may also be used; however, whether or not they are always needed is not clear. Propofol is believed to work at least partly via a receptor for GABA. Propofol was discovered in 1977 ...
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HM Prison Hydebank Wood
His Majesty's Prison, Hydebank Wood (normally known as just Hydebank) is a women's prison located in South Belfast. Young male offenders A young offenders centre (YOC) holding young male prisoners is located on the same site. The YOC houses young males between 18 and 24 years of age, and the site has also been used at times to hold immigration detainees. The institution put a great deal of effort into improving the diet of young offenders and this transformed many of them for the better.''The Guardian ''The Guardian'' is a British daily newspaper. It was founded in 1821 as ''The Manchester Guardian'', and changed its name in 1959. Along with its sister papers ''The Observer'' and ''The Guardian Weekly'', ''The Guardian'' is part of the Gu ...'' (London) 8 August 201Doing porridge: prison, school and hospital meals put to the test/ref> External links Northern Ireland prison service References Prisons in Northern Ireland Young Offender Institutions in Northern Ireland ...
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HM Prison Maghaberry
HMP Maghaberry was built on the site of RAF Maghaberry, a World War II airfield near Lisburn, Northern Ireland, which was used as a flying station by the Royal Air Force and also as a transit airfield for the United States Army Air Forces. At the end of the war, the airfield was run down and bought back from the Air Ministry in 1957 by Edward Thomas Boyes who then farmed the old airfield with his sons until the Northern Ireland Office began work on the prison in 1976. Mourne House, which held all female prisoners, young offenders, and remands, was the first part of the new prison to be opened in March 1986. This followed the closure of the existing women's prison at HMP Armagh. The male prison became fully operational on 2 November 1987. Following the closure of HMP Belfast on 31 March 1996, Maghaberry became the adult committal prison in Northern Ireland. Two new accommodation blocks were opened in 1999. In 2003, the Steele report recommended options to make Maghaberry saf ...
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Aaron Hogg
According to Abrahamic religions, Aaron ''′aharon'', ar, هارون, Hārūn, Greek (Septuagint): Ἀαρών; often called Aaron the priest ()., group="note" ( or ; ''’Ahărōn'') was a prophet, a high priest, and the elder brother of Moses. Knowledge of Aaron, along with his brother Moses, exclusively comes from religious texts, such as the Hebrew Bible, Bible and the Quran. The Hebrew Bible relates that, unlike Moses, who grew up in the Egyptian royal court, Aaron and his elder sister Miriam remained with their kinsmen in the eastern border-land of Egypt ( Goshen). When Moses first confronted the Egyptian king about the enslavement of the Israelites, Aaron served as his brother's spokesman ("prophet") to the Pharaoh (). Part of the Law given to Moses at Sinai granted Aaron the priesthood for himself and his male descendants, and he became the first High Priest of the Israelites. Aaron died before the Israelites crossed the Jordan river. According to the Book of Numb ...
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Northern Ireland Prisoner Ombudsman
Northern may refer to the following: Geography * North, a point in direction * Northern Europe, the northern part or region of Europe * Northern Highland, a region of Wisconsin, United States * Northern Province, Sri Lanka * Northern Range, a range of hills in Trinidad Schools * Northern Collegiate Institute and Vocational School (NCIVS), a school in Sarnia, Canada * Northern Secondary School, Toronto, Canada * Northern Secondary School (Sturgeon Falls), Ontario, Canada * Northern University (other), various institutions * Northern Guilford High School, a public high school in Greensboro, North Carolina Companies * Arriva Rail North, a former train operating company in northern England * Northern Bank, commercial bank in Northern Ireland * Northern Foods, based in Leeds, England * Northern Pictures, an Australian-based television production company * Northern Rail, a former train operating company in northern England * Northern Railway of Canada, a defunct railway ...
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Cannabis (drug)
Cannabis, also known as marijuana among List of names for cannabis, other names, is a psychoactive drug from the cannabis plant. Native to Central or South Asia, the cannabis plant has been used as a drug for both Recreational marijuana, recreational and Entheogenic use of cannabis, entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used by Cannabis smoking, smoking, Vaporizer (inhalation device), vaporizing, Cannabis edible, within food, or Tincture of cannabis, as an extract. Cannabis has various effects of cannabis, mental and physical effects, which include euphoria, altered states of mind and Cannabis and time perception, sense of time, difficulty concentrating, Cannabis and memory, impaired short-term memory, impaired motor skill, body mo ...
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Sexual Health
Sexual and reproductive health (SRH) is a field of research, healthcare, and social activism that explores the health of an individual's reproductive system and sexual wellbeing during all stages of their life. The term can also be further defined more broadly within the framework of the World Health Organization's (WHO) definition of health―as "a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity"― to denote sexual wellbeing, encompassing the ability of an individual to have responsible, satisfying and safe sex and the freedom to decide if, when and how often to do so. UN agencies in particular define sexual and reproductive health as including both physical and psychological well-being vis-à-vis sexuality. A further interpretation includes access to sex education, access to safe, effective, affordable and acceptable methods of birth control, as well as access to appropriate health care services, as the ability of ...
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SSRIs
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs increase the extracellular level of the neurotransmitter serotonin by limiting its reabsorption (reuptake) into the presynaptic cell. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having strong affinity for the serotonin transporter and only weak affinity for the norepinephrine and dopamine transporters. SSRIs are the most widely prescribed antidepressants in many countries. The efficacy of SSRIs in mild or moderate cases of depression has been disputed and may or may not be outweighed by side effects, especially in adolescent populations. Medical uses The main indication for SSRIs is major depressive disorder; however, they are frequently prescribed for anxiety disorders, such as social anxiety disorder, general ...
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