MDR Dusty Miller
MDR may refer to: Biology * MDR1, an ATP-dependent cellular efflux pump affording multiple drug resistance * Mammalian Diving reflex * Medical device reporting * Multiple drug resistance Multiple drug resistance (MDR), multidrug resistance or multiresistance is antimicrobial resistance shown by a species of microorganism to at least one antimicrobial drug in three or more antimicrobial categories. Antimicrobial categories are c ..., when a microorganism has become resistant to multiple drugs Technology * Managed Detection and Response, a type of computer Managed security service * Massive Data Repository, a data storage facility for the United States' Intelligence Community * Sony MDR-V6, a line of studio headphones designed by Sony * Single use medical device reprocessing, Medical device reprocessing * Memory data register, a hardware register where data to be transferred to/from memory are temporarily stored * Mental dead reckoning * ''Merchant discount rate,'' see Merchant ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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MDR1
P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells. More formally, it is an ATP-dependent efflux pump with broad substrate specificity. It exists in animals, fungi, and bacteria, and it likely evolved as a defense mechanism against harmful substances. P-gp is extensively distributed and expressed in the intestinal epithelium where it pumps xenobiotics (such as toxins or drugs) back into the intestinal lumen, in liver cells where it pumps them into bile ducts, in the cells of the proximal tubule of the kidney where it pumps them into urinary filtrate (in the proximal tubule), and in the capillary endothelial cells composing the blood–brain barrier and blood–testis barrier, where it pumps them back into the capillar ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Multifactor Dimensionality Reduction
Multifactor dimensionality reduction (MDR) is a statistical approach, also used in machine learning automatic approaches, for detecting and characterizing combinations of attributes or independent variables that interact to influence a dependent or class variable. MDR was designed specifically to identify nonadditive interactions among discrete variables that influence a binary outcome and is considered a nonparametric and model-free alternative to traditional statistical methods such as logistic regression. The basis of the MDR method is a constructive induction or feature engineering algorithm that converts two or more variables or attributes to a single attribute. This process of constructing a new attribute changes the representation space of the data. The end goal is to create or discover a representation that facilitates the detection of nonlinear or nonadditive interactions among the attributes such that prediction of the class variable is improved over that of the original ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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MD (other)
MD, Md, mD or md may refer to: Places * Moldova (ISO country code MD) * Maryland (US postal abbreviation MD) * Magdeburg (vehicle plate prefix MD), a city in Germany * Mödling District (vehicle plate prefix MD), in Lower Austria, Austria People * Muhammad (name) or Mohammed (Md) Arts, entertainment, and media Music * ' or ' (MD or m.d.; "right hand"), in piano scores * Music director * Mini Disc Other arts, entertainment, and media * ''MDs'' (TV series), 2002 * ', ("Materials and discussions for the analysis of classical texts"), an Italian journal Brands and enterprises * Air Madagascar, IATA airline code * McDonnell Douglas aircraft model prefix * MD Helicopters Science and technology Biology and medicine * Doctor of Medicine, a medical degree * Medial dorsal nucleus, a cluster of neurons in the thalamus * Muscular dystrophy, a group of diseases involving breakdown of skeletal muscles * Ménière's disease, a disorder of the inner ear * MD (Ayurveda), a degree in Indian ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Republican Democratic Movement
The Republican Democratic Movement (french: Mouvement démocratique républicain, MDR) was a political party in Rwanda. History The party was established in 1991,Profiles: Kagame's opponents BBC News, 22 August 2003 after the (MRND) lost its monopoly on politics and opposition parties were legalised. The MDR took its name from MDR-Parmehutu, the ruling party in the early 1960s. Like Parmehutu, the MDR's primary base of political support was Hutus in the centre of the countr ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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List Of French Expressions In English
Many words in the English vocabulary are of French origin, most coming from the Anglo-Norman spoken by the upper classes in England for several hundred years after the Norman Conquest, before the language settled into what became Modern English. English words of French origin, such as ''art'', ''competition'', ''force'', ''machine'', and ''table'' are pronounced according to English rules of phonology, rather than French, and are commonly used by English speakers without any consciousness of their French origin. This article, on the other hand, covers French words and phrases that have entered the English lexicon without ever losing their character as Gallicisms: they remain unmistakably "French" to an English speaker. They are most common in written English, where they retain French diacritics and are usually printed in italics. In spoken English, at least some attempt is generally made to pronounce them as they would sound in French; an entirely English pronunciation is reg ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mitteldeutscher Rundfunk
Mitteldeutscher Rundfunk (MDR; ''Central German Broadcasting'') is the public broadcaster for the federal states of Thuringia, Saxony and Saxony-Anhalt in Germany. Established in January 1991, its headquarters are in Leipzig, with regional studios in Dresden, Erfurt and Magdeburg. MDR is a member of the ARD consortium of public broadcasters in Germany. MDR broadcasts its own television channel to the three states it serves and also contributes programming to the first German TV channel ( Das Erste), and broadcasts a number of radio channels. History Origins The Mitteldeutsche Rundfunk AG (MIRAG) was founded on 22 January 1924 in Leipzig. It aired its first program on 1 March 1924 at 14:30 CET. During the '' Gleichschaltung'' in the Nazi era, the MIRAG was transferred to the "Reichssender Leipzig" in 1934. After the end of the Second World War, the Soviet Military Administration in Germany temporarily licensed "Radio Leipzig" in 1945, which only existed for a few months unti ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Medical Device
A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assurance before regulating governments allow marketing of the device in their country. As a general rule, as the associated risk of the device increases the amount of testing required to establish safety and efficacy also increases. Further, as associated risk increases the potential benefit to the patient must also increase. Discovery of what would be considered a medical device by modern standards dates as far back as c. 7000 BC in Baluchistan where Neolithic dentists used flint-tipped drills and bowstrings. Study of archeology and Roman medical literature also indicate that many types of medical devices were in widespread use during the time of ancient Rome. In the United States it wasn't until the Federal Food, Drug, and Cosmetic Act (F ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Regulation (European Union)
A regulation is a legal act of the European Union that becomes immediately enforceable as law in all member states simultaneously. Regulations can be distinguished from directives which, at least in principle, need to be transposed into national law. Regulations can be adopted by means of a variety of legislative procedures depending on their subject matter. Description The description of regulations can be found in Article 288 of the Treaty on the Functioning of the European Union (formerly Article 249 TEC). Article 288 To exercise the Union's competences, the institutions shall adopt regulations, directives, decisions, recommendations and opinions. A regulation shall have general application. It shall be binding in its entirety and directly applicable in all Member States. A directive shall be binding, as to the result to be achieved, upon each Member State to which it is addressed, but shall leave to the national authorities the choice of form and methods. A decision ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Regulation (EU) 2017/745
Regulation (EU) 2017/745 is a regulation of the European Union on the clinical investigation and sale of medical devices for human use. It repeals Directive 93/42/EEC (MDD), which concerns medical devices, and Directive 90/385/EEC, which concerns active implantable medical devices, on 26 May 2021. The regulation was published on 5 April 2017 and came into force on 25 May 2017. Originally approved medical devices will have a transition time of three years (until 26 May 2021) to meet new requirements. Changes Changes compared to the Medical Device Directive include changes in device classification and device scope, stricter oversight of manufacturers by Notified Bodies, introduction of the "Person Responsible for Regulatory Compliance" (PRRC) and of the economic operator concept, the requirement of Unique Device Identification marking for devices, EUDAMED registration (see below), UDI requirements, and increased post-market surveillance activities. Scope and classificatio ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Classified Information In The United States
The United States government classification system is established under Executive Order 13526, the latest in a long series of executive orders on the topic beginning in 1951. Issued by President Barack Obama in 2009, Executive Order 13526 replaced earlier executive orders on the topic and modified the regulations codified to 32 C.F.R. 2001. It lays out the system of classification, declassification, and handling of national security information generated by the U.S. government and its employees and contractors, as well as information received from other governments. The desired degree of secrecy about such information is known as its sensitivity. Sensitivity is based upon a calculation of the damage to national security that the release of the information would cause. The United States has three levels of classification: Confidential, Secret, and Top Secret. Each level of classification indicates an increasing degree of sensitivity. Thus, if one holds a Top Secret security cle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mandar Language
Mandar (also Andian, Manjar, Mandharsche) is an Austronesian language spoken by the Mandar ethnic group living in West Sulawesi province of Indonesia, especially in the coastal regencies of Majene and Polewali Mandar, as well as in a few settlements in the islands of Pangkep District (also known as the Spermonde Archipelago) and Ujung Lero, a small peninsula near Pare-Pare). It is written in the Lontara script. The ethnic Mandar people The Mandarese are an ethnic group in the Indonesian province of West Sulawesi in Sulawesi. The Mandar language belongs to the Northern subgroup of the South Sulawesi languages group of the Malayo-Polynesian branch of the Austronesian language f ... are closely related to three other groups living in South Sulawesi: Bugis, Makassar, and Toraja. References External links Mandar alphabet and pronunciationat ''Omniglot'' *http://unicode-table.com/en/sections/buginese/ Languages of Indonesia South Sulawesi languages {{austronesia ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Moldavian Democratic Republic
The Moldavian Democratic Republic (MDR; ro, Republica Democratică Moldovenească, ), also known as the Moldavian Republic, was a state proclaimed on by the ''Sfatul Țării'' (National Council) of Bessarabia, elected in October–November 1917 following the February Revolution and the start of the disintegration of the Russian Empire. The ''Sfatul Țării'' was its legislative body, while the "Council of Directors General", renamed the "Council of Ministers" after the Declaration of Independence, was its government. The Republic was proclaimed on 2/15 December 1917, as a result of the Declaration of the Rights of the Peoples of Russia. The anthem of the country was ''Deșteaptă-te, române!''. History Summarized The brief history of the 1917-1918 Moldavian Democratic Republic can be divided into three periods: the period of autonomy within Russia, the period of independence, and the period of federation with Romania. On 2/15 December, Moldavia proclaimed itself a c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |