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MADS-box
The MADS box is a conserved sequence motif. The genes which contain this motif are called the MADS-box gene family. The MADS box encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box reported by various researchers varies somewhat, but typical lengths are in the range of 168 to 180 base pairs, i.e. the encoded MADS domain has a length of 56 to 60 amino acids. There is evidence that the MADS domain evolved from a sequence stretch of a type II topoisomerase in a common ancestor of all extant eukaryotes. Origin of name and history of research The first MADS-box gene to be identified was ''ARG80'' from budding yeast, ''Saccharomyces cerevisiae'', but was at that time not recognized as a member of a large gene family. The MADS-box gene family got its name later as an acronym referring to the four founding members, ig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MEF2
In the field of molecular biology, myocyte enhancer factor-2 (Mef2) proteins are a family of transcription factors which through control of gene expression are important regulators of cellular differentiation and consequently play a critical role in embryonic development. In adult organisms, Mef2 proteins mediate the stress response in some tissues. Mef2 proteins contain both MADS-box and Mef2 DNA-binding domains. Discovery Mef2 was originally identified as a transcription factor complex through promoter analysis of the muscle creatine kinase (mck) gene to identify nuclear factors interacting with the mck enhancer region during muscle differentiation. Three human mRNA coding sequences designated RSRF (Related to Serum Response Factor) were cloned and shown to dimerize, bind a consensus sequence similar to the one present in the MCK enhancer region, and drive transcription. RSRFs were subsequently demonstrated to encode human genes now named Mef2A, Mef2B and Mef2D. Spec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Günter Theißen
Günter Theißen (born 16 January 1962 in Mönchengladbach) is a German geneticist. He holds the chair of genetics at the University of Jena. Life Theißen studied biology at the University of Düsseldorf and did his PhD in 1991 with Rolf Wagner at that university. From 1992–2001, he was a group leader at the Max Planck Institute for Plant Breeding Research in Cologne. He did his second doctorate (Habilitation) at the University of Cologne in 2000. In 2001, he was appointed professor at the University of Münster. In 2002, he was appointed to hold the chair of genetics at the University of Jena. Scientific work In his research, Theißen deals, among other things, with molecular genetics and evolution of plant development. In particular, he and his group investigate special transcription factor In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription (genetics), transcription of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serum Response Factor
Serum response factor, also known as SRF, is a transcription factor protein. Function Serum response factor is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). SRF is important during the development of the embryo, as it has been linked to the formation of mesoderm. In the fully developed mammal, SRF is crucial for the growth of skeletal muscle. Interaction of SRF with other proteins, such as steroid hormone receptors, may contribute to regulation of muscle growth by steroids ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agamous
AGAMOUS (AG) is a homeotic gene and MADS-box transcription factor protein present in ''Arabidopsis thaliana ''Arabidopsis thaliana'', the thale cress, mouse-ear cress or arabidopsis, is a small plant from the mustard family (Brassicaceae), native to Eurasia and Africa. Commonly found along the shoulders of roads and in disturbed land, it is generally ...''. The TAIR AGI number is AT4G18960. The identity of a floral organ is determined by particular combinations of the protein products of homeotic genes. These proteins act within regions of undifferentiated cells known as the floral meristem and give the cells a developmental fate. The presence of the ''AGAMOUS ''homeotic gene product in Arabidopsis results in the cessation of all meristem activity and cells procede to facilitate the development of stamens and carpels. In the absence of the AG protein, stamens and carpels do not develop and meristem activity continues, resulting in flowers consisting of many whorls of sepals a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription Factors
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of TFs is to regulate—turn on and off—genes in order to make sure that they are expressed in the desired cells at the right time and in the right amount throughout the life of the cell and the organism. Groups of TFs function in a coordinated fashion to direct cell division, cell growth, and cell death throughout life; cell migration and organization (body plan) during embryonic development; and intermittently in response to signals from outside the cell, such as a hormone. There are approximately 1600 TFs in the human genome. Transcription factors are members of the proteome as well as regulome. TFs work alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zea Mays
Maize (; ''Zea mays''), also known as corn in North American English, is a tall stout Poaceae, grass that produces cereal grain. It was domesticated by indigenous peoples of Mexico, indigenous peoples in southern Mexico about 9,000 years ago from wild teosinte. Native Americans planted it alongside beans and Cucurbita, squashes in the Three Sisters (agriculture), Three Sisters polyculture. The leafy Plant stem, stalk of the plant gives rise to male inflorescences or tassels which produce pollen, and female inflorescences called ear (botany), ears. The ears yield grain, known as Corn kernels, kernels or seeds. In modern commercial varieties, these are usually yellow or white; other varieties can be of many colors. Maize relies on humans for its propagation. Since the Columbian exchange, it has become a staple food in many parts of the world, with the List of most valuable crops and livestock products, total production of maize surpassing that of wheat and rice. Much maize is u ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antirrhinum Majus
''Antirrhinum majus'', the common snapdragon (often – especially in horticulture – simply "snapdragon"), is a species of flowering plant belonging to the genus ''Antirrhinum''. The plant was placed in the family Plantaginaceae following a revision of its prior classical family, Scrophulariaceae. The common name "snapdragon", originates from the flowers' reaction to having their throats squeezed, which causes the "mouth" of the flower to snap open like a dragon's mouth. It is widely used as an ornamental plant in borders and as a cut flower. It is perennial but usually cultivated as an annual plant. The species has been in culture since the 15th century. Description It is an herbaceous perennial plant, growing to 0.5–1 m tall, rarely up to 2 m. The leaves are spirally arranged, broadly lanceolate, 1–7 cm long and 2–2.5 cm broad. The upper glandular stalk is stalk-round, sometimes woody to the middle. The opposite leaves are simple, elliptic or ovate to br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tunicate1
In biology, a tunica (, ; : tunicae) is a layer, coat, sheath, or similar covering. The word came to English from the Neo-Latin of science and medicine. Its literal sense is about the same as that of the word ''tunic'', with which it is cognate. In biology, one of its senses used to be the taxonomic name of a genus of plants, but the nomenclature has been revised and those plants are now included in the genus '' Petrorhagia''. In modern biology in general, ''tunica'' occurs as a technical or anatomical term mainly in botany and zoology. It usually refers to membranous structures that line or cover particular organs. In many such contexts, ''tunica'' is used interchangeably with ''tunic'' according to preference. An organ or organism that has a tunic(a) may be said to be ''tunicate'', as in a ''tunicate bulb''. This adjective ''tunicate'' is not to be confused with the noun ''tunicate'', which refers to a member of the subphylum '' Tunicata''. Botanical and related usages In botany ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the publishing house of the University of Oxford. It is the largest university press in the world. Its first book was printed in Oxford in 1478, with the Press officially granted the legal right to print books by decree in 1586. It is the second-oldest university press after Cambridge University Press, which was founded in 1534. It is a department of the University of Oxford. It is governed by a group of 15 academics, the Delegates of the Press, appointed by the Vice Chancellor, vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, Walton Street, Oxford, opposite Somerville College, Oxford, Somerville College, in the inner suburb of Jericho, Oxford, Jericho. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society Of Plant Biologists
The American Society of Plant Biologists (ASPB) is a non-profit professional society for research and education in plant science with over 4,000 members world-wide. It was founded in 1924, as the American Society of Plant Physiologists (ASPP). The name was changed to the American Society of Plant Biologists (ASPB) as of 2001. Membership in the society is open to any person from any country who deals with physiology, molecular biology, environmental biology, cell biology and plant biophysics or related issues. The society publishes the peer-reviewed journals ''Plant Physiology'' (1926-) and ''The Plant Cell'' (1989-) as well as ''ASPB News''. The American Society of Plant Biologists also has partnered with the Society for Experimental Biology, and Wiley to publish an online-only science journal ''Plant Direct''. In 2000, it published the first edition of the textbook ''Biochemistry & Molecular Biology of Plants''. The society has given the Charles Reid Barnes Life Membership A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
