M. Xenopi
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M. Xenopi
''Mycobacterium xenopi'' is a slow-growing scotochromogenic species of ''Mycobacterium''. It was first reported by Schwabacher in 1959, having been isolated in lesions found on a ''Xenopus laevis'', but the possibility of human infection was not confirmed until 1965. It has been cultured from hot and cold water taps, hospital hot water generators and storage tanks, and other environmental sources. It has low pathogenicity in humans, and where infections have been found they are closely associated with immunocompromised individuals, such as an extrapulmonary malignancy, alcoholism, diabetes mellitus, or immunosuppressive therapy. Pulmonary disease may be chronic, subacute, or acute; symptoms are indistinguishable from those associated with disease caused by ''M. kansasii''. Radiographic findings with ''M. xenopi'' pulmonary disease are variable but most often include upper lobe cavitary abnormalities similar to tuberculosis. On solid media, there is an egg next colony produced ...
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Scotochromogenic
Scotochromogenic bacteria develop pigment in the dark. Runyon Group II nontuberculous mycobacteria such as Mycobacterium gordonae ''Mycobacterium gordonae'' is a species of '' Mycobacterium'' named for Ruth E. Gordon. It is a species of the phylum Actinomycetota (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), b ... are examples but the term could apply to many other organisms. References Bacteria {{Bacteria-stub ...
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Mycobacterium
''Mycobacterium'' is a genus of over 190 species in the phylum Actinomycetota, assigned its own family, Mycobacteriaceae. This genus includes pathogens known to cause serious diseases in mammals, including tuberculosis ('' M. tuberculosis'') and leprosy ('' M. leprae'') in humans. The Greek prefix ''myco-'' means 'fungus', alluding to this genus' mold-like colony surfaces. Since this genus has cell walls with Gram-positive and Gram-negative features, acid-fast staining is used to emphasize their resistance to acids, compared to other cell types. Metabolism and Morphology Mycobacteria are aerobic with 0.2-0.6 µm wide and 1.0-10 µm long rod shapes. They are generally non-motile, except for the species ''Mycobacterium marinum'', which has been shown to be motile within macrophages. Mycobacteria possess capsules and most do not form endospores. ''M. marinum'' and perhaps ''M. bovis'' have been shown to sporulate; however, this has been contested by further research. The disti ...
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Lesion
A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classification or naming convention for lesions. Since lesions can occur anywhere in the body and the definition of a lesion is so broad, the varieties of lesions are virtually endless. Generally, lesions may be classified by their patterns, their sizes, their locations, or their causes. They can also be named after the person who discovered them. For example, Ghon lesions, which are found in the lungs of those with tuberculosis, are named after the lesion's discoverer, Anton Ghon. The characteristic skin lesions of a varicella zoster virus infection are called '' chickenpox''. Lesions of the teeth are usually called dental caries. Location Lesions are often classified by their tissue types or locations. For example, a "skin lesion" or a " bra ...
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Xenopus Laevis
The African clawed frog (''Xenopus laevis'', also known as the xenopus, African clawed toad, African claw-toed frog or the ''platanna'') is a species of African aquatic frog of the family Pipidae. Its name is derived from the three short claws on each hind foot, which it uses to tear apart its food. The word ''Xenopus'' means 'strange foot' and ''laevis'' means 'smooth'. The species is found throughout much of Sub-Saharan Africa (Nigeria and Sudan to South Africa),Weldon; du Preez; Hyatt; Muller; and Speare (2004). Origin of the Amphibian Chytrid Fungus.' Emerging Infectious Diseases 10(12). and in isolated, introduced populations in North America, South America, Europe, and Asia. All species of the family Pipidae are tongueless, toothless and completely aquatic. They use their hands to shove food in their mouths and down their throats and a hyobranchial pump to draw or suck things in their mouth. Pipidae have powerful legs for swimming and lunging after food. They also use the ...
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Pathogenicity
In biology, a pathogen ( el, πάθος, "suffering", "passion" and , "producer of") in the oldest and broadest sense, is any organism or agent that can produce disease. A pathogen may also be referred to as an infectious agent, or simply a germ. The term ''pathogen'' came into use in the 1880s. Typically, the term ''pathogen'' is used to describe an ''infectious'' microorganism or agent, such as a virus, bacterium, protozoan, prion, viroid, or fungus. Small animals, such as helminths and insects, can also cause or transmit disease. However, these animals are usually referred to as parasites rather than pathogens. The scientific study of microscopic organisms, including microscopic pathogenic organisms, is called microbiology, while parasitology refers to the scientific study of parasites and the organisms that host them. There are several pathways through which pathogens can invade a host. The principal pathways have different episodic time frames, but soil has the longes ...
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Immunocompromised
Immunodeficiency, also known as immunocompromisation, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection and environmental factors, such as nutrition. Immunocompromisation may also be due to genetic diseases/flaws such as SCID. In clinical settings, immunosuppression by some drugs, such as steroids, can either be an adverse effect or the intended purpose of the treatment. Examples of such use is in organ transplant surgery as an anti- rejection measure and in patients with an overactive immune system, as in autoimmune diseases. Some people are born with intrinsic defects in their immune system, or primary immunodeficiency. A person who has an immunodeficiency of any kind is said to be immunocompromised. An immunocompromised individual may particular ...
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Biological Type
In biology, a type is a particular specimen (or in some cases a group of specimens) of an organism to which the scientific name of that organism is formally attached. In other words, a type is an example that serves to anchor or centralizes the defining features of that particular taxon. In older usage (pre-1900 in botany), a type was a taxon rather than a specimen. A taxon is a scientifically named grouping of organisms with other like organisms, a set that includes some organisms and excludes others, based on a detailed published description (for example a species description) and on the provision of type material, which is usually available to scientists for examination in a major museum research collection, or similar institution. Type specimen According to a precise set of rules laid down in the International Code of Zoological Nomenclature (ICZN) and the International Code of Nomenclature for algae, fungi, and plants (ICN), the scientific name of every taxon is almost al ...
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American Type Culture Collection
ATCC or the American Type Culture Collection is a nonprofit organization which collects, stores, and distributes standard reference microorganisms, cell lines and other materials for research and development. Established in 1925 to serve as a national center for depositing and distributing microbiological specimens, ATCC has since grown to distribute in over 150 countries.Clark, W.A. and D. H. Geary. 1974. The Story of the American Type Culture Collection – Its History and Development (1899-1973). Advances in Applied Microbiology 17:295-309. It is now the largest general culture collection in the world. Products and collections ATCC's collections include a wide range of biological materials for research, including cell lines, microorganisms and bioproducts. The organization holds a collection of more than 3,000 human and animal cell lines and an additional 1,200 hybridomas. ATCC's microorganism collection includes a collection of more than 18,000 strains of bacteria, as well as ...
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Acid-fast Bacilli
Acid-fastness is a physical property of certain bacterial and eukaryotic cells, as well as some sub-cellular structures, specifically their resistance to decolorization by acids during laboratory staining procedures. Once stained as part of a sample, these organisms can resist the acid and/or ethanol-based decolorization procedures common in many staining protocols, hence the name ''acid-fast''. The mechanisms of acid-fastness vary by species, although the most well-known example is in the genus ''Mycobacterium'', which includes the species responsible for tuberculosis and leprosy. The acid-fastness of ''Mycobacteria'' is due to the high mycolic acid content of their cell walls, which is responsible for the staining pattern of poor absorption followed by high retention. Some bacteria may also be partially acid-fast, such as ''Nocardia''. Acid-fast organisms are difficult to characterize using standard microbiological techniques, though they can be stained using concentrated dyes, ...
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Nontuberculous Mycobacteria
Nontuberculous mycobacteria (NTM), also known as environmental mycobacteria, atypical mycobacteria and mycobacteria other than tuberculosis (MOTT), are mycobacteria which do not cause tuberculosis or leprosy (also known as Hansen's disease). NTM do cause pulmonary diseases that resemble tuberculosis. Mycobacteriosis is any of these illnesses, usually meant to exclude tuberculosis. They occur in many animals, including humans and are commonly found in soil and water. Introduction Mycobacteria are a family of small, rod-shaped bacilli that can be classified into three main groups for the purpose of diagnosis and treatment: * ''Mycobacterium tuberculosis'' complex, which can cause tuberculosis: '' M. tuberculosis'', '' M. bovis'', '' M. africanum'', '' M. microti'' and '' M. canetti'' * '' M. leprae'' and '' M. lepromatosis'', which cause Hansen's disease, also called leprosy * Nontuberculous mycobacteria (NTM) are all the other mycobacteria that can cause pulmonary disease resemblin ...
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