Lyman C. Craig
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Lyman C. Craig
Lyman C. Craig (born 1906 in Palmyra Township, Warren County, Iowa; died 1974) was a chemical researcher who worked at The Rockefeller Institute for Medical Research from 1933 onward. In 1944 he published a seminal work on countercurrent distribution, which became an important separation technique. Craig continued to develop the theory, improve the apparatus and devise new applications of the countercurrent distribution into the 1970s. Countercurrent distribution not only proved to be a useful separation technique, it also inspired the development of the field of countercurrent chromatography. In 1950, Craig invented the rotary evaporator which is a necessary equipment in most chemical labs. He also invented the Craig tube, an apparatus used in small-scale chemistry, in particular for recrystallization. He received recognition from his peers and several honors for his scientific accomplishments. He was elected to the National Academy of Sciences in 1950. He was the recipient of the 1 ...
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Iowa
Iowa () is a state in the Midwestern region of the United States, bordered by the Mississippi River to the east and the Missouri River and Big Sioux River to the west. It is bordered by six states: Wisconsin to the northeast, Illinois to the east and southeast, Missouri to the south, Nebraska to the west, South Dakota to the northwest, and Minnesota to the north. During the 18th and early 19th centuries, Iowa was a part of French Louisiana and Spanish Louisiana; its state flag is patterned after the flag of France. After the Louisiana Purchase, people laid the foundation for an agriculture-based economy in the heart of the Corn Belt. In the latter half of the 20th century, Iowa's agricultural economy transitioned to a diversified economy of advanced manufacturing, processing, financial services, information technology, biotechnology, and green energy production. Iowa is the 26th most extensive in total area and the 31st most populous of the 50 U.S. states, with a populat ...
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Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classified among "R2: Doctoral Universities – High research activity." Rockefeller is the oldest biomedical research institute in the United States. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Sciences, 17 members of the National Academy of Medicine, seven Lasker Award recipients, and five Nobel laureates. As of March 2022, a total of 26 Nobel laureates have been affiliated with Rockefeller University. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine' ...
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Countercurrent Distribution
Countercurrent distribution (CCD, also spelled "counter current" distribution) is an analytical chemistry technique which was developed by Lyman C. Craig in the 1940s. Countercurrent distribution is a separation process that is founded on the principles of liquid–liquid extraction where a chemical compound is distributed (partitioned) between two immiscible liquid phases (oil and water for example) according to its relative solubility in the two phases. The simplest form of liquid-liquid extraction is the partitioning of a mixture of compounds between two immiscible liquid phases in a separatory funnel. This occurs in five steps: 1) preparation of the separatory funnel with the two phase solvent system, 2) introduction of the compound mixture into the separatory funnel, 3) vigorous shaking of the separatory funnel to mix the two layers and allow for mass transfer of compounds in and out of the phases, 4) The contents of the separatory funnel are allowed to settle back into two dist ...
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Countercurrent Chromatography
Countercurrent chromatography (CCC, also counter-current chromatography) is a form of liquid–liquid chromatography that uses a liquid stationary phase that is held in place by inertia of the molecules composing the stationary phase accelerating toward the center of a centrifuge due to centripetal force and is used to separate, identify, and quantify the chemical components of a mixture. In its broadest sense, countercurrent chromatography encompasses a collection of related liquid chromatography techniques that employ two immiscible liquid phases without a solid support. The two liquid phases come in contact with each other as at least one phase is pumped through a column, a hollow tube or a series of chambers connected with channels, which contains both phases. The resulting dynamic mixing and settling action allows the components to be separated by their respective solubilities in the two phases. A wide variety of two-phase solvent systems consisting of at least two immiscible ...
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Rotary Evaporator
A rotary evaporator (rotovap) is a device used in chemical laboratories for the efficient and gentle removal of solvents from samples by evaporation. When referenced in the chemistry research literature, description of the use of this technique and equipment may include the phrase "rotary evaporator", though use is often rather signaled by other language (e.g., "the sample was evaporated under reduced pressure"). Rotary evaporators are also used in molecular cooking for the preparation of distillates and extracts. A simple rotary evaporator system was invented by Lyman C. Craig. It was first commercialized by the Swiss companBüchiin 1957. Walter Büchi developed a world first commercial rotary evaporator, which separates substances with different boiling points, and greatly simplifies work in research laboratories. In research the most common form is the 1L bench-top unit, whereas large scale (e.g., 20L-50L) versions are used in pilot plants in commercial chemical operations. De ...
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Craig Tube
A Craig tube is an item of apparatus used in small-scale (up to about 100 mg) preparative and analytical chemistry, particularly for recrystallisation. It was invented by Lyman C. Craig and Otto W. Post. A Craig tube consists of two parts. The first is a stout-walled test tube with a working volume of about 1-5 ml (say, 7-8 cm in length and 1-1.5 cm in diameter). There is a constriction towards the open end of the tube. The second is a loosely-fitting generally-cylindrical stopper, possibly with a teardrop-shaped head, of glass or of another inert material such as PTFE, which seats on the constriction. Recrystallisation is carried out in the usual manner, by dissolving the solid to be purified in a solvent and causing crystals of the solid to form. The stopper can be used to protect the solution from atmospheric contamination. The crystals are separated from the mother liquor by placing the tube and stopperinvertedin a centrifuge tube, followed by centrifugation. T ...
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Industrial & Engineering Chemistry Research
''Industrial & Engineering Chemistry Research'' is a peer-reviewed scientific journal published by the American Chemical Society covering all aspects of chemical engineering. The editor-in-chief is Phillip E. Savage ( Pennsylvania State University). History The journal was established in 1909 as the ''Journal of Industrial & Engineering Chemistry''. It was renamed in 1930 as ''Industrial & Engineering Chemistry'' before obtaining its current title in 1970. From 1911 to 1916 it was edited by Milton C. Whitaker. From 1921 to 1942 it was edited by Dr. Harrison E. Howe. The journal ''I&EC Product Research and Development'' was established in 1962. It was renamed ''Product R&D'' in 1969 and renamed again in 1978 as ''Industrial & Engineering Chemistry Product Research and Development''. In 1986, it and the journals ''Industrial & Engineering Chemistry Fundamentals'' and ''Industrial & Engineering Chemistry Process Design and Development'', both also established in 1962, were comb ...
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National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ...
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Albert Lasker Award For Basic Medical Research
The Albert Lasker Award for Basic Medical Research is one of the prizes awarded by the Lasker Foundation for a fundamental discovery that opens up a new area of biomedical science. The award frequently precedes a Nobel Prize in Medicine; almost 50% of the winners have gone on to win one. List of Albert Lasker Award for Basic Medical Research recipients {, , Valign="top", {, class="wikitable" ! Year !! Recipient , - , Rowspan="3", 2022 , , Richard O. Hynes , - , , Erkki Ruoslahti , - , , Timothy A. Springer , - , Rowspan="3", 2021 , , Karl Deisseroth , - , , Peter Hegemann , - , , Dieter Oesterhelt , - , Rowspan="1", 2020 , , not awarded   , - , Rowspan="2", 2019 , , Max Dale Cooper , - , , Jacques Miller , - , Rowspan="2", 2018 , , C. David Allis , - , , Michael Grunstein , - , Rowspan="1", 2017 , , Michael N. Hall , - , Rowspan="3", 2016 , , William Kaelin, Jr. , - , , Peter J. Ratcliffe , - , , Gregg L. Semenza , - , R ...
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Nobel Prize In Chemistry
) , image = Nobel Prize.png , alt = A golden medallion with an embossed image of a bearded man facing left in profile. To the left of the man is the text "ALFR•" then "NOBEL", and on the right, the text (smaller) "NAT•" then "MDCCCXXXIII" above, followed by (smaller) "OB•" then "MDCCCXCVI" below. , awarded_for = Outstanding contributions in chemistry , presenter = Royal Swedish Academy of Sciences , location = Stockholm, Sweden , reward = 9 million SEK (2017) , year = 1901 , holder = Carolyn R. Bertozzi, Morten P. Meldal and Karl Barry Sharpless (2022) , most_awards = Frederick Sanger and Karl Barry Sharpless (2) , website nobelprize.org, previous = 2021 , year2=2022, main=2022, next=2023 The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for ...
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People From Warren County, Iowa
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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