Little Nicky (cat)
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Little Nicky (cat)
Little Nicky (born October 17, 2004) is the first commercially produced clone of a cat. He was produced from the DNA of a 17-year-old Maine Coon cat named Nicky who died in 2003. Little Nicky's owner, a north Texas woman named Julie (whose last name was not released) paid $50,000 to have Nicky cloned. Little Nicky's owner reported that the cat shared many characteristics with his predecessor, including a similar personality and appearance. Origin and Cloning The cloning of Little Nicky was performed by the California-based company Genetic Savings & Clone, which later closed in 2006. This followed the first successful cloning of a cat by the company in conjunction with Texas A&M University. The cloning was performed by the chromatin transfer technique, a variant of nuclear transfer. The cloning of Little Nicky was a result of an offer by the company called the "Nine Lives Extravaganza" launched in 2004. Ethical controversy Groups such as the Humane Society of the United States, ...
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Cloning
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of Cell (biology), cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millio ...
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Maine Coon
The Maine Coon is a large domesticated cat breed. It is one of the oldest natural breeds in North America. The breed originated in the U.S. state of Maine, where it is the official state cat. The breed was popular in cat shows in the late 19th century, but its existence became threatened when long-haired breeds from overseas were introduced in the early 20th century. The Maine Coon has since made a comeback and is now the third most popular pedigreed cat breed in the world. The Maine Coon is a large and social cat, which could be the reason why it has a reputation of being referred to as "the gentle giant." The Maine Coon is predominantly known for its size and dense coat of fur which helps the large feline to survive in the harsh climate of Maine, the state from which they originated. The Maine Coon is often cited as having " dog-like" characteristics. Due to the large size of this feline, professionals have noticed certain health problems arising in the breed, including fel ...
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Texas
Texas (, ; Spanish language, Spanish: ''Texas'', ''Tejas'') is a state in the South Central United States, South Central region of the United States. At 268,596 square miles (695,662 km2), and with more than 29.1 million residents in 2020, it is the second-largest U.S. state by both List of U.S. states and territories by area, area (after Alaska) and List of U.S. states and territories by population, population (after California). Texas shares borders with the states of Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, New Mexico to the west, and the Mexico, Mexican States of Mexico, states of Chihuahua (state), Chihuahua, Coahuila, Nuevo León, and Tamaulipas to the south and southwest; and has a coastline with the Gulf of Mexico to the southeast. Houston is the List of cities in Texas by population, most populous city in Texas and the List of United States cities by population, fourth-largest in the U.S., while San Antonio is the second most pop ...
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California
California is a U.S. state, state in the Western United States, located along the West Coast of the United States, Pacific Coast. With nearly 39.2million residents across a total area of approximately , it is the List of states and territories of the United States by population, most populous U.S. state and the List of U.S. states and territories by area, 3rd largest by area. It is also the most populated Administrative division, subnational entity in North America and the 34th most populous in the world. The Greater Los Angeles area and the San Francisco Bay Area are the nation's second and fifth most populous Statistical area (United States), urban regions respectively, with the former having more than 18.7million residents and the latter having over 9.6million. Sacramento, California, Sacramento is the state's capital, while Los Angeles is the List of largest California cities by population, most populous city in the state and the List of United States cities by population, ...
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Genetic Savings & Clone
Genetic Savings & Clone, Inc. was a company headquartered in Sausalito, California that offered commercial pet gene banking and cloning services, between 2004 and 2006. History The company was founded as a result of the efforts to clone Lou Hawthorne's favorite family dog, Missy. The Missyplicity project generated enough interest that Lou Hawthorne decided to build a company devoted to dog and cat cloning. The company opened for business in February 2000, funded production of the first cloned cat, CC, in 2001, and launched its pet cloning service in February 2004, operating a "petbank", to which pet owners could send tissue samples for later use in cloning. The company delivered the world's first commercially cloned cat, Little Nicky, in December 2004. Little Nicky was sold to a Texas woman for a reported US$50,000. He is a genetic twin of "Nicky," a 17-year-old Maine Coon cat that had been kept as a pet. Musician Liam Lynch's cat was cloned after its death, presumably making hi ...
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CC (cat)
CC, for "CopyCat" ''or'' "Carbon Copy" (December 22, 2001 – March 3, 2020), was a brown tabby and white domestic shorthair and the first cloned pet. She was cloned by scientists at Texas A&M University in conjunction with Genetic Savings & Clone Inc. CC's surrogate mother was a tabby, but her genetic donor, Rainbow, was a calico domestic shorthair. The difference in hair coloration between CC and Rainbow is due to X-inactivation and epigenetic re-programming, which normally occurs in a fertilized embryo before implantation. In September 2006, CC gave birth to four kittens. The litter was fathered naturally by another lab cat named Smokey. It included two males named Tim and Zip and one female named Tess. Another kitten (a female) was stillborn. This incident was the first time a cloned pet gave birth. Throughout her life, CC appeared to be free of the cloning-related health problems that have arisen in some other animal clones. "CC has always been a perfectly normal cat ...
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Texas A&M University
Texas A&M University (Texas A&M, A&M, or TAMU) is a public, land-grant, research university in College Station, Texas. It was founded in 1876 and became the flagship institution of the Texas A&M University System in 1948. As of late 2021, Texas A&M has the largest student body in the United States, and is the only university in Texas to hold simultaneous designations as a land, sea, and space grant institution. In 2001, it was inducted into the Association of American Universities. The university's students, alumni, and sports teams are known as Aggies, and its athletes compete in eighteen varsity sports as a member of the Southeastern Conference. The university was the first public higher-education institution in Texas; it opened for classes on October 4, 1876, as the Agricultural and Mechanical College of Texas (A.M.C.) under the provisions of the 1862 Morrill Land-Grant Act. In the following decades, the college grew in size and scope, expanding to its largest enrol ...
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Nuclear Transfer
Nuclear transfer is a form of cloning. The step involves removing the DNA from an oocyte (unfertilised egg), and injecting the nucleus which contains the DNA to be cloned. In rare instances, the newly constructed cell will divide normally, replicating the new DNA while remaining in a pluripotent state. If the cloned cells are placed in the uterus of a female mammal, a cloned organism develops to term in rare instances. This is how Dolly the Sheep and many other species were cloned. Cows are commonly cloned to select those that have the best milk production. On 24 January 2018, two monkey clones were reported to have been created with the technique for the first time. Despite this, the low efficiency of the technique has prompted some researchers, notably Ian Wilmut, creator of Dolly the cloned sheep, to abandon it. Tools and reagents Nuclear transfer is a delicate process that is a major hurdle in the development of cloning technology. Materials used in this procedure are ...
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Humane Society Of The United States
The Humane Society of the United States (HSUS) is an American nonprofit organization that focuses on animal welfare and opposes animal-related cruelties of national scope. It uses strategies that are beyond the abilities of local organizations. It works on issues including pets, wildlife, farm animals, horses and other Equus (genus), equines, and animals used in research, Animal testing, testing and education.Simon M. Shane. (January 14, 2014Interview with Wayne Pacelle, president of HSUS Egg-Cite.com. As of 2001, the group's major campaigns targeted factory farming, animal blood sports, the fur trade, puppy mills, and wildlife abuse. The HSUS is based in Washington, D.C., and was founded in 1954 by journalist Fred Myers and Helen Jones, Larry Andrews, Marcia Glaser and Oliver M Evans. In 2013, the ''Chronicle of Philanthropy'' ranked HSUS as the 136th largest charity in the US in its Philanthropy 400 listing.October 16, 2011Lists from the Philanthropy 400 ''The Chronicle of Phil ...
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Best Friends Animal Society
Best Friends Animal Society, (BFAS) founded in its present form in 1993, is an American nonprofit 501(c)(3) animal welfare organization. BFAS does outreach nationwide with shelters, rescue groups and members to promote pet adoption, no-kill animal rescue, and spay-and-neuter practices. Best Friends has a 3-star 'Give With Confidence' rating from Charity Navigator. History The group originated in England in 1966 as the Process Church of the Final Judgment, co-founded by Mary Ann MacLean, who was married to former church member and Best Friends Animal Society co-founder Gabriel Depeyer, and who lived on Best Friends' sanctuary grounds until her 2005 death. The Foundation church relocated animals from its Arizona ranch to property in Kanab, Utah, in 1984. In 1991, the church was renamed Best Friends Animal Sanctuary, which became a tax-exempt, nonprofit charity, and in 2003, renamed Best Friends Animal Society. In 2019, Best Friends Animal Society and Southern Utah University beg ...
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Animal Welfare
Animal welfare is the well-being of non-human animals. Formal standards of animal welfare vary between contexts, but are debated mostly by animal welfare groups, legislators, and academics. Animal welfare science uses measures such as longevity, disease, immunosuppression, behavior, physiology, and reproduction, although there is debate about which of these best indicate animal welfare. Respect for animal welfare is often based on the belief that nonhuman animals are sentient and that consideration should be given to their well-being or suffering, especially when they are under the care of humans. These concerns can include how animals are slaughtered for food, how they are used in scientific research, how they are kept (as pets, in zoos, farms, circuses, etc.), and how human activities affect the welfare and survival of wild species. There are two forms of criticism of the concept of animal welfare, coming from diametrically opposite positions. One view, held by some think ...
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Pet Cloning
Commercial animal cloning is the cloning of animals for commercial purposes, currently, including livestock, competition camels and horses, pets, medical uses, endangered and extinct animals, as first demonstrated in 1996 for Dolly the sheep. Cloning methods Moving or copying all (or nearly all) genes from one animal to form a second, genetically nearly identical, animal is usually done through one of three methods: the Roslin technique, the Honolulu technique, and Artificial Twinning. The first two of these involve a process known as somatic cell nuclear transfer. In this process, an oocyte is taken from a surrogate mother and put through enucleation, a process that removes the nucleus from inside the oocyte. Somatic cells are then taken from the animal that is being cloned, transferred into the blank oocyte in order to provide genetic material, and fused with the oocyte using an electrical current. The oocyte is then activated and re-inserted into the surrogate mother. The end ...
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