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Lipiduria
Lipiduria or lipuria is the presence of lipids in the urine. Lipiduria is most frequently observed in nephrotic syndrome where it is passed as lipoproteins along with other proteins. It has also been reported as a sign following fat embolism. When lipiduria occurs, epithelial cells or macrophages contain endogenous fats. When filled with numerous fat droplets, such cells are called oval fat bodies. Oval fat bodies exhibit a "Maltese cross" configuration under polarized light microscopy. The Maltese cross appearance occurs because of its liquid-crystalline structure giving it a double refraction (birefringence Birefringence is the optical property of a material having a refractive index that depends on the polarization and propagation direction of light. These optically anisotropic materials are said to be birefringent (or birefractive). The birefring ...). See also * Urostealith References Urine {{med-sign-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipid
Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The functions of lipids include storing energy, signaling, and acting as structural components of cell membranes. Lipids have applications in the cosmetic and food industries, and in nanotechnology. Lipids may be broadly defined as hydrophobic or amphiphilic small molecules; the amphiphilic nature of some lipids allows them to form structures such as vesicles, multilamellar/unilamellar liposomes, or membranes in an aqueous environment. Biological lipids originate entirely or in part from two distinct types of biochemical subunits or "building-blocks": ketoacyl and isoprene groups. Using this approach, lipids may be divided into eight categories: fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, saccharolipids, and polyketides (derived from condensati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urine
Urine is a liquid by-product of metabolism in humans and in many other animals. Urine flows from the kidneys through the ureters to the urinary bladder. Urination results in urine being excretion, excreted from the body through the urethra. Cell (biology), Cellular metabolism generates many by-products that are rich in nitrogen and must be clearance (medicine), cleared from the Circulatory system, bloodstream, such as urea, uric acid, and creatinine. These by-products are expelled from the body during urination, which is the primary method for excreting water-soluble chemicals from the body. A urinalysis can detect nitrogenous wastes of the mammalian body. Urine plays an important role in the earth's nitrogen cycle. In balanced ecosystems, urine fertilizes the soil and thus helps plants to grow. Therefore, Reuse of excreta, urine can be used as a fertilizer. Some animals use it to territory (animal)#Scent marking, mark their territories. Historically, aged or fermented urine (kn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nephrotic Syndrome
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure. Causes include a number of kidney diseases such as focal segmental glomerulosclerosis, membranous nephropathy, and minimal change disease. It may also occur as a complication of diabetes or lupus. The underlying mechanism typically involves damage to the glomeruli of the kidney. Diagnosis is typically based on urine testing and sometimes a kidney biopsy. It differs from nephritic syndrome in that there are no red blood cells in the urine. Treatment is directed at the underlying cause. Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. A low salt diet and limiting fluids is often recommended. About 5 per 100,00 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipoprotein
A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat) molecules in water, as in blood plasma or other extracellular fluids. They consist of a triglyceride and cholesterol center, surrounded by a phospholipid outer shell, with the hydrophilic portions oriented outward toward the surrounding water and lipophilic portions oriented inward toward the lipid center. A special kind of protein, called apolipoprotein, is embedded in the outer shell, both stabilising the complex and giving it a functional identity that determines its role. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins. Examples include plasma lipoprotein particles ( HDL, LDL, IDL, VLDL and chylomicrons). Subgroups of these plasma particles are primary drivers or modulators of atherosclerosis. Scope Transmembrane lipoproteins Some transmembrane proteolipids, especially those found in bacteria, are referred ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fat Embolism
Fat embolism syndrome occurs when fat enters the blood stream (fat embolism) and results in symptoms. Symptoms generally begin within a day. This may include a petechial rash, decreased level of consciousness, and shortness of breath. Other symptoms may include fever and decreased urine output. The risk of death is about 10%. Fat embolism most commonly occurs as a result of fractures of bones such as the femur or pelvis. Other potential causes include pancreatitis, orthopedic surgery, bone marrow transplant, and liposuction. The underlying mechanism involved widespread inflammation. Diagnosis is based on symptoms. Treatment is mostly supportive care. This may involve oxygen therapy, intravenous fluids, albumin, and mechanical ventilation. While small amounts of fat commonly occur in the blood after a bone fracture, fat embolism syndrome is rare. The condition was first diagnosed in 1862 by Zenker. Signs and symptoms Symptoms of fat embolism syndrome (FES) can start from 12 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maltese Cross
The Maltese cross is a cross symbol, consisting of four " V" or arrowhead shaped concave quadrilaterals converging at a central vertex at right angles, two tips pointing outward symmetrically. It is a heraldic cross variant which developed from earlier forms of eight-pointed crosses in the 16th century. Although chiefly associated with the Knights Hospitaller (Order of St. John, now the Sovereign Military Order of Malta), and by extension with the island of Malta, it has come to be used by a wide array of entities since the early modern period, notably the Order of Saint Stephen, the city of Amalfi, the Polish Order of the White Eagle (1709), the Prussian order ''Pour le Mérite'' (1740), and the Bavarian Military Merit Order (1866). Unicode defines a character named "Maltese cross" in the Dingbats range at code point U+2720 (✠); however most computer fonts render the code point as a cross pattée. History The Knights Hospitaller during the Crusades used a plain L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polarized Light Microscopy
Polarized light microscopy can mean any of a number of optical microscopy techniques involving polarized light. Simple techniques include illumination of the sample with polarized light. Directly transmitted light can, optionally, be blocked with a polariser orientated at 90 degrees to the illumination. More complex microscopy techniques which take advantage of polarized light include differential interference contrast microscopy and interference reflection microscopy. Scientists will often use a device called a polarizing plate to convert natural light into polarized light. These illumination techniques are most commonly used on birefringent samples where the polarized light interacts strongly with the sample and so generating contrast with the background. Polarized light microscopy is used extensively in optical mineralogy. History Although the invention of the polarizing microscope is typically attributed to David Brewster around 1815, Brewster clearly acknowledges the prio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birefringence
Birefringence is the optical property of a material having a refractive index that depends on the polarization and propagation direction of light. These optically anisotropic materials are said to be birefringent (or birefractive). The birefringence is often quantified as the maximum difference between refractive indices exhibited by the material. Crystals with non-cubic crystal structures are often birefringent, as are plastics under mechanical stress. Birefringence is responsible for the phenomenon of double refraction whereby a ray of light, when incident upon a birefringent material, is split by polarization into two rays taking slightly different paths. This effect was first described by Danish scientist Rasmus Bartholin in 1669, who observed it in calcite, a crystal having one of the strongest birefringences. In the 19th century Augustin-Jean Fresnel described the phenomenon in terms of polarization, understanding light as a wave with field components in transverse polariz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urostealith
Urostealith is a fatty or resinous substance identified by the Austrian chemist J. F. Heller in 1845 as the main constituent of some bladder stones. Giuliano dall'Olio (2008), ''Nuovo componente dei calcoli vescicali — L’ “urostealite ” di Heller''. (In Italian) RIMeL - IJLaM, volume 4, issue 1, Società Italiana Medicina di LaboratorioOnline versionaccessed on 2009-07-30. According to Heller's and other contemporary descriptions, urostealith is a soft brown substance, insoluble in water, sparingly soluble in alcohol and easily soluble in ether. Upon heating it softens at first, then expands and carbonizes before melting. It dissolves in solutions of sodium carbonate, and the latter was successfully used by Heller to dissolve and break up stones in a patient's bladder. Urostealith stones seem to be very rare. S. Materazzi, R. Curini, G. D'Ascenzo, and A. D. Magri (1995), ''TG-FTIR coupled analysis applied to the studies in urolithiasis: characterization of human renal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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