Leptomeningeal Collateral Circulation
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Leptomeningeal Collateral Circulation
The leptomeningeal collateral circulation (also known as leptomeningeal Anastomosis, anastomoses or pial collaterals) is a network of small blood vessels in the brain that connects branches of the middle, anterior and posterior cerebral arteries (Middle cerebral artery, MCA, Anterior cerebral artery, ACA, and Posterior cerebral artery, PCA), with variation in its precise anatomy between individuals. During a stroke, leptomeningeal collateral vessels allow limited blood flow when other, larger blood vessels provide inadequate blood supply to a part of the brain. Structure Leptomeningeal collaterals lie within the Meninges#Leptomeninges, leptomeninges, the two deep layers of the meninges called the pia mater and the arachnoid mater. Their diameter has been measured at approximately 300 micrometers, but there is variability between individuals in the size, quantity and location of these vessels, and between either hemisphere within the same subject. ''Inter-territorial'' end to e ...
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Brain
A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a vertebrate's body. In a human, the cerebral cortex contains approximately 14–16 billion neurons, and the estimated number of neurons in the cerebellum is 55–70 billion. Each neuron is connected by synapses to several thousand other neurons. These neurons typically communicate with one another by means of long fibers called axons, which carry trains of signal pulses called action potentials to distant parts of the brain or body targeting specific recipient cells. Physiologically, brains exert centralized control over a body's other organs. They act on the rest of the body both by generating patterns of muscle activity and by driving the secretion of chemicals called hormones. This centralized control allows rapid and coordinated respon ...
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TOF MRI Angiography Of Right Middle Cerebral Artery Stenosis
TOF may refer to: * The Original Factory Shop, a British discount department store * Time of flight, a principle of several scientific methods ** Time-of-flight camera, a camera system that analyzes time of flight of the light it captures, to resolve depth ** Time-of-flight mass spectrometry uses the time of flight of an ion in the gas phase to resolve its mass-to-charge ratio * Tetralogy of Fallot, a congenital heart defect * TOF, British abbreviation for Tracheoesophageal fistula, an abnormal connection between the esophagus and the trachea * Turnover frequency, a rate in chemical reactions * TOF, IATA airport code for Bogashevo Airport, in Tomsk, Russia * ''Torch of Freedom'', a novel by David Weber * TOF, MTR station code for Tong Fong Tsuen stop, in Hong Kong * TOF (Top of Form), relates to the print start position i.e. the position the printer starts printing from at the top of the page * ''Tower of Fantasy ''Tower of Fantasy'' () is a free-to-play open world action rol ...
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Primate
Primates are a diverse order of mammals. They are divided into the strepsirrhines, which include the lemurs, galagos, and lorisids, and the haplorhines, which include the tarsiers and the simians (monkeys and apes, the latter including humans). Primates arose 85–55 million years ago first from small terrestrial mammals, which adapted to living in the trees of tropical forests: many primate characteristics represent adaptations to life in this challenging environment, including large brains, visual acuity, color vision, a shoulder girdle allowing a large degree of movement in the shoulder joint, and dextrous hands. Primates range in size from Madame Berthe's mouse lemur, which weighs , to the eastern gorilla, weighing over . There are 376–524 species of living primates, depending on which classification is used. New primate species continue to be discovered: over 25 species were described in the 2000s, 36 in the 2010s, and three in the 2020s. Primates have large bra ...
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Penumbra (medicine)
In pathology and anatomy the penumbra is the area surrounding an ischemic event such as thrombotic or embolic stroke. Immediately following the event, blood flow and therefore oxygen transport is reduced locally, leading to hypoxia of the cells near the location of the original insult. This can lead to hypoxic cell death (infarction) and amplify the original damage from the ischemia; however, the penumbra area may remain viable for several hours after an ischemic event due to the collateral arteries that supply the penumbral zone. As time elapses after the onset of stroke, the extent of the penumbra tends to decrease; therefore, in the emergency department a major concern is to protect the penumbra by increasing oxygen transport and delivery to cells in the danger zone, thereby limiting cell death. The existence of a penumbra implies that salvage of the cells is possible. There is a high correlation between the extent of spontaneous neurological recovery and the volume of penum ...
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Otto Heubner
Johann Otto Leonhard Heubner (January 21, 1843 – October 17, 1926) was a German internist and pediatrician who was a native of Mühltroff. He studied medicine at the University of Leipzig, and in 1867 became an assistant to Carl Reinhold August Wunderlich (1815–1877) at Leipzig. He later founded a children's hospital and clinic in Leipzig, and in 1891 was appointed to the chair of pediatrics. In 1894 he moved to Berlin, where he became director of the children's clinic and polyclinic at the Charité. Heubner is considered one of the fathers of pediatric medicine. He also made important contributions to the treatment of infectious and gastrointestinal diseases. He was instrumental in improving infant mortality at the Charité, and introduced aseptic practices into the hospital environment. With Max Rubner (1854–1932), he investigated energy metabolism in infants, creating the concept of a nutrition quotient. With Eduard Heinrich Henoch (1820–1910), he was among the ...
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Thomas Willis
Thomas Willis FRS (27 January 1621 – 11 November 1675) was an English doctor who played an important part in the history of anatomy, neurology and psychiatry, and was a founding member of the Royal Society. Life Willis was born on his parents' farm in Great Bedwyn, Wiltshire, where his father held the stewardship of the manor. He was a kinsman of the Willys baronets of Fen Ditton, Cambridgeshire. He graduated M.A. from Christ Church, Oxford in 1642.Willis, Thomas
The Galileo Project. Galileo.rice.edu. Retrieved on 17 July 2012.
In the Civil War years he was a royalist, dispossessed of the family farm at by Parliamentary forces. In the 1640s, Willis was one of ...
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Otto Heubner 2
Otto is a masculine German given name and a surname. It originates as an Old High German short form (variants ''Audo'', '' Odo'', ''Udo'') of Germanic names beginning in ''aud-'', an element meaning "wealth, prosperity". The name is recorded from the 7th century ( Odo, son of Uro, courtier of Sigebert III). It was the name of three 10th-century German kings, the first of whom was Otto I the Great, the first Holy Roman Emperor, founder of the Ottonian dynasty. The Gothic form of the prefix was ''auda-'' (as in e.g. '' Audaþius''), the Anglo-Saxon form was ''ead-'' (as in e.g. '' Eadmund''), and the Old Norse form was '' auð-''. The given name Otis arose from an English surname, which was in turn derived from ''Ode'', a variant form of ''Odo, Otto''. Due to Otto von Bismarck, the given name ''Otto'' was strongly associated with the German Empire in the later 19th century. It was comparatively frequently given in the United States (presumably in German American families) ...
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Intracranial Hemorrhage
Intracranial hemorrhage (ICH), also known as intracranial bleed, is bleeding within the skull. Subtypes are intracerebral bleeds ( intraventricular bleeds and intraparenchymal bleeds), subarachnoid bleeds, epidural bleeds, and subdural bleeds. More often than not it ends in a lethal outcome. Intracerebral bleeding affects 2.5 per 10,000 people each year. Signs and symptoms Intracranial hemorrhage is a serious medical emergency because the buildup of blood within the skull can lead to increases in intracranial pressure, which can crush delicate brain tissue or limit its blood supply. Severe increases in intracranial pressure (ICP) can cause brain herniation, in which parts of the brain are squeezed past structures in the skull. Causes Trauma is the most common cause of intracranial hemorrhage. It can cause epidural hemorrhage, subdural hemorrhage, and subarachnoid hemorrhage. Other condition such as hemorrhagic parenchymal contusion and cerebral microhemorrhages can also ...
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Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis in which the wall of the artery develops abnormalities, called lesions. These lesions may lead to narrowing due to the buildup of atheroma, atheromatous plaque. At onset there are usually no symptoms, but if they develop, symptoms generally begin around middle age. When severe, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney problems, depending on which Artery, arteries are affected. The exact cause is not known and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory markers, high blood pressure, diabetes, smoking, obesity, family history, genetic, and an unhealthy diet. Atheroma, Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. The narrowing of Artery, arteries limits the flow of oxygen-rich blood to parts of the body. Diagnosis is based upon a physical exam, ele ...
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Stent
In medicine, a stent is a metal or plastic tube inserted into the lumen of an anatomic vessel or duct to keep the passageway open, and stenting is the placement of a stent. A wide variety of stents are used for different purposes, from expandable coronary, vascular and biliary stents, to simple plastic stents that allow urine to flow between kidney and bladder. "Stent" is also used as a verb to describe the placement of such a device, particularly when a disease such as atherosclerosis has pathologically narrowed a structure such as an artery. A stent is different from a shunt. A shunt is a tube that connects two previously unconnected parts of the body to allow fluid to flow between them. Stents and shunts can be made of similar materials, but perform two different tasks. Stent types Etymology The current accepted origin of the word ''stent'' is that it derives from the name of an English dentist, Charles Thomas Stent (1807–1885), notable for his advances in the fi ...
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term memory, remembering recent events. As the disease advances, symptoms can include primary progressive aphasia, problems with language, Orientation (mental), disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and challenging behaviour, behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an alle ...
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CT Scan
A computed tomography scan (CT scan; formerly called computed axial tomography scan or CAT scan) is a medical imaging technique used to obtain detailed internal images of the body. The personnel that perform CT scans are called radiographers or radiology technologists. CT scanners use a rotating X-ray tube and a row of detectors placed in a gantry (medical), gantry to measure X-ray Attenuation#Radiography, attenuations by different tissues inside the body. The multiple X-ray measurements taken from different angles are then processed on a computer using tomographic reconstruction algorithms to produce Tomography, tomographic (cross-sectional) images (virtual "slices") of a body. CT scans can be used in patients with metallic implants or pacemakers, for whom magnetic resonance imaging (MRI) is Contraindication, contraindicated. Since its development in the 1970s, CT scanning has proven to be a versatile imaging technique. While CT is most prominently used in medical diagnosis, ...
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