Leo Sternbach
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Leo Sternbach
Leo Sternbach (May 7, 1908 – September 28, 2005) was a Polish American chemist who is credited with first synthesizing benzodiazepines, the main class of tranquilizers. Background and family Sternbach was born on May 7, 1908, in Opatija, Kingdom of Hungary, Austro-Hungarian Empire, to an upper middle class Jewish family. He had a younger brother, Giusi. Ha-Kol (Glasilo Židovske zajednice u Hrvatskoj); Sanja Dukić; Povratak velikana u rodnu Opatiju; stranica 40, 41; broj 94, svibanj / lipanj 2006. His father Michael Abracham Sternbach was from the Polish city of Przemyśl in Galicia (then part of Austria-Hungary), and his mother Piroska (née Cohn) Sternbach was from Orosháza, Hungary. Sternbach's parents met and married in Opatija where they both lived. The family lived in modest conditions, in a rented four-room apartment on the third floor of the "Vila Jadran" (Villa Adriatic), near the pharmacy owned by Sternbach's father. Sternbach attended a private German school ...
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Opatija
Opatija (; it, Abbazia; german: Sankt Jakobi) is a town and a municipality in Primorje-Gorski Kotar County in western Croatia. The traditional seaside resort on the Kvarner Gulf is known for its Mediterranean climate and its historic buildings reminiscent of the Austrian Riviera. Geography Opatija is located northwest of the regional capital Rijeka, about from Trieste by rail and from Pula by road. The city is geographically on the Istrian peninsula, though not in Istria County. The tourist resort is situated on the Kvarner Gulf, part of the Adriatic coast, in a sheltered position at the foot of Učka massif, with the ''Vojak'' peak reaching at a height of . cesnus, the municipality had 10,661 inhabitants in total, of which 5,715 lived in the urban settlement. The town is a popular summer and winter resort, with average high temperatures of 10 °C in winter, and 32 °C in summer. Opatija is surrounded by beautiful woods of bay laurel. The whole sea-coast to the no ...
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Bielitz
Bielsko (german: Bielitz, cs, Bílsko) was until 1950 an independent town situated in Cieszyn Silesia, Poland. In 1951 it was joined with Biała Krakowska to form the new town of Bielsko-Biała. Bielsko constitutes the western part of that town. Bielsko was founded by the Duchy of Cieszyn, Cieszyn Piast dukes in the late 13th century on the grounds of village later called Stare Bielsko (''Old Bielsko''), on the Biała River (Vistula basin), Biała River. It was first mentioned in a written document in 1312. Originally settled by Germans, it became the largest German-language center (''Deutsche Sprachinsel Bielitz'') in the Duchy of Teschen, and remained so until the end of World War II. In 1572 it gained autonomy as the Duchy of Bielsko, Duchy (State) of Bielsko. During the 18th century a rapid development of textile industry occurred, and at the beginning of the 19th century more than 500 weaving, weavers worked in the town. After the 1920 division of Cieszyn Silesia between P ...
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Diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken by mouth, inserted into the rectum, injected into muscle, injected into a vein or used as a nasal spray. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects begin after 15 to 60 minutes. Common side-effects include sleepiness and trouble with coordination. Serious side effects are rare. They include increased risk of suicide, decreased breathing, and an increased risk of seizures if used too frequently in those with epilepsy. Occasionally, excitement or agitation may occur. Long-term use can result in tolerance, dependence, and withdrawal symptoms on dose reduction ...
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Chlordiazepoxide
Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of Drug withdrawal, withdrawal from Alcohol (drug), alcohol and other drugs. Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life. The drug has amnesic, anticonvulsant, anxiolytic, hypnotic, sedative and skeletal muscle relaxant properties. Chlordiazepoxide was patented in 1958 and approved for medical use in 1960. It was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use. Medical uses Chlordiazepoxide is indicated for the short-term (2–4 weeks) treatment of anxiety that is severe and disab ...
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Science History Institute
The Science History Institute is an institution that preserves and promotes understanding of the history of science. Located in Philadelphia, Pennsylvania, it includes a library, museum, archive, research center and conference center. It was founded in 1982 as a joint venture of the American Chemical Society and the University of Pennsylvania, as the Center for the History of Chemistry (CHOC). The American Institute of Chemical Engineers (AIChE) became a co-founder in 1984. It was renamed the Chemical Heritage Foundation (CHF) in 1992, and moved two years later to the institution's current location, 315 Chestnut Street in Old City, Philadelphia, Old City. On December 1, 2015, CHF merged with the Life Sciences Foundation, creating an organization that covers "the history of the life sciences and biotechnology together with the history of the chemical sciences and engineering." As of February 1, 2018, the organization was renamed the Science History Institute, to reflect its wide ...
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Nutley, New Jersey
Nutley is a township in Essex County, New Jersey, United States. As of the 2020 United States census, the township's population was 30,143. What is now Nutley was originally incorporated as Franklin Township by an act of the New Jersey Legislature on February 18, 1874, from portions of Belleville Township. Nutley was incorporated as a town on March 5, 1902, replacing Franklin Township.Snyder, John P''The Story of New Jersey's Civil Boundaries: 1606–1968'' Bureau of Geology and Topography; Trenton, New Jersey; 1969. p. 130 for Nutley, p. 128 for Franklin Township. Accessed June 1, 2012. In 1981, the town was one of seven Essex County municipalities to pass a referendum to become a township, joining four municipalities that had already made the change, of what would ultimately be more than a dozen Essex County municipalities to reclassify themselves as townships in order take advantage of federal revenue sharing policies that allocated townships a greater share of government ai ...
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Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth largest pharmaceutical company in the world by revenue, and the leading provider of cancer treatments globally. The company controls the American biotechnology company Genentech, which is a wholly owned affiliate, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States-based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020 were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, and Maja Oeri a further 5% apart), with Swiss pharma firm Novartis owning a furth ...
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Basel
, french: link=no, Bâlois(e), it, Basilese , neighboring_municipalities= Allschwil (BL), Hégenheim (FR-68), Binningen (BL), Birsfelden (BL), Bottmingen (BL), Huningue (FR-68), Münchenstein (BL), Muttenz (BL), Reinach (BL), Riehen (BS), Saint-Louis (FR-68), Weil am Rhein (DE-BW) , twintowns = Shanghai, Miami Beach , website = www.bs.ch Basel ( , ), also known as Basle ( ),french: Bâle ; it, Basilea ; rm, label= Sutsilvan, Basileia; other rm, Basilea . is a city in northwestern Switzerland on the river Rhine. Basel is Switzerland's third-most-populous city (after Zürich and Geneva) with about 175,000 inhabitants. The official language of Basel is (the Swiss variety of Standard) German, but the main spoken language is the local Basel German dialect. Basel is commonly considered to be the cultural capital of Switzerland and the city is famous for its many museums, including the Kunstmuseum, which is the first collection of art accessibl ...
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Swiss Federal Institute Of Technology In Zurich
(colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , academic_staff = 6,612 (including doctoral students, excluding 527 professors of all ranks, 34% female, 65% foreign nationals) (full-time equivalents 2021) , administrative_staff = 3,106 (40% female, 19% foreign nationals, full-time equivalents 2021) , students = 24,534 (headcount 2021, 33.3% female, 37% foreign nationals) , undergrad = 10,642 , postgrad = 8,299 , doctoral = 4,460 , other = 1,133 , address = Rämistrasse 101CH-8092 ZürichSwitzerland , city = Zürich , coor = , campus = Urban , language = German, English (Masters and upwards, sometimes Bachelor) , affiliations = CESAER, EUA, GlobalTech, IARU, IDEA League, UNITECH , website ethz.ch, colors = Black and White , logo = ETH Zürich Logo black.svg ETH Zür ...
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Leopold Ružička
Leopold Ružička (; born Lavoslav Stjepan Ružička; 13 September 1887 – 26 September 1976) was a Croatian-Swiss scientist and joint winner of the 1939 Nobel Prize in Chemistry "for his work on polymethylenes and higher terpenes" "including the first chemical synthesis of male sex hormones." He worked most of his life in Switzerland, and received eight doctor ''honoris causa'' in science, medicine, and law; seven prizes and medals; and twenty-four honorary memberships in chemical, biochemical, and other scientific societies. Early life Ružička was born in Vukovar, Kingdom of Croatia-Slavonia, Lands of the Crown of Saint Stephen, Austro-Hungarian Empire (today in Croatia). His family of craftsmen and farmers was mostly of Croat origin, with a Czech great grandparent, Ružička, and a great grandmother and a great grandfather from Austria.Now available from He lost his father, Stjepan, at the age of four, and his mother, Amalija Sever, took him and his younger brother Stje ...
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Sigmund Fränkel
Sigmund Fraenkel or Sigmund Fränkel (22 May 1868, in Krakau – 7 June 1939, in Geneva) was a Polish-born chemist who lived and worked in Austria, and is notable for being the head of the ''Ludwig-Spiegler-Stiftung'' in Vienna from 1904 and his work in the field of Physiological chemistry, notably on the chemistry of the thyroid gland. He studied at the University of Vienna under Ernst Ludwig (1842-1915) and Ernst Wilhelm von Brücke, in Prague under Karl Hugo Huppert (1832–1904) and in Freiburg im Breisgau. In 1892 he obtained his doctorate in medicine in Vienna, and in 1896 he was Private Tutor in Medicinal chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and developme .... Works * ''Die Arzneimittel-Synthese auf Grundlage der Beziehungen zwischen chemischen Aufbau und Wirkung : für ...
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Vienna
en, Viennese , iso_code = AT-9 , registration_plate = W , postal_code_type = Postal code , postal_code = , timezone = CET , utc_offset = +1 , timezone_DST = CEST , utc_offset_DST = +2 , blank_name = Vehicle registration , blank_info = W , blank1_name = GDP , blank1_info = € 96.5 billion (2020) , blank2_name = GDP per capita , blank2_info = € 50,400 (2020) , blank_name_sec1 = HDI (2019) , blank_info_sec1 = 0.947 · 1st of 9 , blank3_name = Seats in the Federal Council , blank3_info = , blank_name_sec2 = GeoTLD , blank_info_sec2 = .wien , website = , footnotes = , image_blank_emblem = Wien logo.svg , blank_emblem_size = Vienna ( ; german: Wien ; ba ...
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