Leloir Institute
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Leloir Institute
The Leloir Institute is a non-profit research center in Buenos Aires specializing in biochemistry, cellular biology, molecular biology, and related activities. Overview The research center was inaugurated in 1947 by way of an initiative of University of Buenos Aires Physiology Professors Bernardo Houssay and Luis Leloir. The project was funded by the philanthropic support of local textile industrialist Jaime Campomar, and Dr. Houssay devoted a share of the proceeds from the Nobel Prize in Physiology he earned that year to the establishment of the institute. Initially located in a belle époque building in the Palermo section of Buenos Aires, the institute was first directed by Dr. Leloir and, following Campomar's death in 1956, it became a recipient of an endowment from both the Rockefeller Institute and the National Institutes of Health, both in the United States. The institute was formally named the Campomar Institute of Research in Biochemistry in 1958, when it was relocate ...
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Leloir Cardini
Luis Federico Leloir (September 6, 1906 – December 2, 1987) was an Argentine physician and biochemist who received the 1970 Nobel Prize in Chemistry for his discovery of the metabolic pathways in lactose. Although born in France, Leloir received the majority of his education at the University of Buenos Aires and was director of the private research group Fundación Instituto Campomar until his death in 1987. His research into sugar nucleotides, carbohydrate metabolism, and renal hypertension garnered international attention and led to significant progress in understanding, diagnosing and treating the congenital disease galactosemia. Luis Leloir is buried in La Recoleta Cemetery, Buenos Aires. Biography Early years Leloir's parents, Federico Augusto Rufino Leloir Bernal and Hortensia Aguirre de Leloir, traveled from Buenos Aires to Paris in the middle of 1906 with the intention of treating Federico's illness. However, Federico died in late August, and a week later Luis was ...
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Oncology
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenome ...
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ...
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Weizmann Institute
The Weizmann Institute of Science ( he, מכון ויצמן למדע ''Machon Vaitzman LeMada'') is a public research university in Rehovot, Israel, established in 1934, 14 years before the State of Israel. It differs from other Israeli universities in that it offers only postgraduate degrees in the natural and exact sciences. It is a multidisciplinary research center, with around 3,800 scientists, postdoctoral fellows, Ph.D. and M.Sc. students, and scientific, technical, and administrative staff working at the institute. As of 2019, six Nobel laureates and three Turing Award winners have been associated with the Weizmann Institute of Science. History Founded in 1934 by Chaim Weizmann and his first team, among them Benjamin M. Bloch, as the Daniel Sieff Research Institute. Weizmann had offered the post of director to Nobel Prize laureate Fritz Haber, but took over the directorship himself after Haber's death en route to Palestine. Before he became President of ...
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Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company – an American aerospace firm which was divested to various firms over time. History The institute was fo ...
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Partners Harvard Medical International
Partners HealthCare International (PHI) provides advisory services and professional consulting to organizations outside the United States. PHI is a subsidiary of Partners HealthCare System, a non-profit health care system based in Boston, Massachusetts. History PHI was founded in 1994 as a subsidiary of Harvard University. From 1994 until 2008, the organization was known as Harvard Medical International, or HMI. Operated as a division of Harvard Medical School, HMI's original focus was to work with institutions around the world — primarily medical schools and health care delivery organizations — interested in developing education programs and health care programs with the help of Harvard professors and the staff of Harvard Medical School. In April 2008, HMI became Partners Harvard Medical International and became part of Partners HealthCare. Since 1994, the company has developed collaborative relationships with institutions in more than 40 countries. Organization PHI's c ...
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Parque Centenario
Parque Centenario is an extensive public park in the Caballito district of Buenos Aires, Argentina. Overview Presiding over a rapidly expanding city, the Buenos Aires City Council in 1908 approved the purchase of a 10 hectare (25 acre) plot belonging to Parmenio Piñero, a local brickmaker, for the purpose of a creating a "Westside Park" (the area was near Buenos Aires' western limits at the time). The project was entrusted to the City Parks Administrator, the renowned French Argentine urbanist Charles Thays, who completed the project in time for the 1910 centennial of the May Revolution (hence the park's name, ''Centenario''). Rerouting two streets, Thays created a circular green space anchored by fountain in the middle. The outer sections of the park were planned for residential development, though these plans were later rescinded. The outermost lots were made available to a number of cultural and scientific institutions, notably the Louis Pasteur Institute (founded in 1927), ...
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Caballito, Buenos Aires
Caballito (; Spanish for "little horse") is a '' barrio'' (neighborhood) of the Argentine capital, Buenos Aires. It is the only ''barrio'' in the administrative division ''Comuna'' 6. It is located in the geographical centre of the city, limited by the following streets and avenues: Rio de Janeiro, Av. Rivadavia, Av. La Plata, Av. Directorio, Curapaligüe, Av. Donato Álvarez, Av. Juan B. Justo, Av. San Martín, and Av. Ángel Gallardo. The name is said to come from the horse-shaped (Spanish ''caballo'') weather vane from a local ''pulpería'' (gauchos' bar); ''Caballito'' meaning "Little horse". Places of interest In Caballito there are numerous points of interest; the "English District" with British style "Fin de Siècle" architecture, the Ferro Carril Oeste football Club (or "Verdolaga"), the "Historical Tramway museum of Buenos Aires", the old "Mercado del Progreso" (Market of Progress) a neighborhood favorite since 1890, the Italian Club and the Portuguese Club. Among ...
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Galactosemia
Galactosemia (British galactosaemia, from Greek γαλακτόζη + αίμα, meaning galactose + blood, accumulation of galactose in blood) is a rare genetic metabolic disorder that affects an individual's ability to metabolize the sugar galactose properly. Galactosemia follows an autosomal recessive mode of inheritance that confers a deficiency in an enzyme responsible for adequate galactose degradation. Friedrich Goppert (1870–1927), a German physician, first described the disease in 1917, with its cause as a defect in galactose metabolism being identified by a group led by Herman Kalckar in 1956. Galactosemia was the second disorder found to be detectable through newborn screening methods by Robert Guthrie. Its incidence is about 1 per 60,000 births for people of European ancestry. In other populations the incidence rate differs. Galactosaemia is about one hundred times more common (1:480 births) in the Irish Traveller population. Symptoms Adults Infants Infan ...
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