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Latex Allergen Testing
FITkit is an immunological test for measuring natural rubber latex (NRL) allergens from a variety of rubber products, such as gloves. Description FITkit is a method for quantification of the major natural rubber latex (NRL) specific allergens: Hev b 1, Hev b 3, Hev b 5 and Hev b 6.02. The sum of four major allergens shows the allergenic potential of NRL products like gloves, condoms, teats, balloons, etc. These tests are based on the enzyme immunometric assay technique and use specific monoclonal antibodies developed against the clinically relevant latex allergens present in NRL products. FITkit is known also under scientific names EIA (enzyme immunoassay) or IEMA (immuno-enzymometric assay). on Icosagen AS homepage. Retrieved 13 May 2009, (PDF file; 1.07 Mb) The main value of FITkit technology is the focus only on those NRL ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Latex
Latex is an emulsion (stable dispersion) of polymer microparticles in water. Latexes are found in nature, but synthetic latexes are common as well. In nature, latex is found as a milky fluid found in 10% of all flowering plants (angiosperms). It is a complex emulsion that coagulates on exposure to air, consisting of proteins, alkaloids, starches, sugars, oils, tannins, resins, and gums. It is usually exuded after tissue injury. In most plants, latex is white, but some have yellow, orange, or scarlet latex. Since the 17th century, latex has been used as a term for the fluid substance in plants, deriving from the Latin word for "liquid". It serves mainly as defense against herbivorous insects. Latex is not to be confused with plant sap; it is a distinct substance, separately produced, and with different functions. The word latex is also used to refer to natural latex rubber, particularly non-vulcanized rubber. Such is the case in products like latex gloves, latex condoms ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glove
A glove is a garment covering the hand. Gloves usually have separate sheaths or openings for each finger and the thumb. If there is an opening but no (or a short) covering sheath for each finger they are called fingerless gloves. Fingerless gloves having one small opening rather than individual openings for each finger are sometimes called gauntlets, though gauntlets are not necessarily fingerless. Gloves which cover the entire hand or fist but do not have separate finger openings or sheaths are called mittens. Mittens are warmer than other styles of gloves made of the same material because fingers maintain their warmth better when they are in contact with each other; reduced surface area reduces heat loss. A hybrid of glove and mitten contains open-ended sheaths for the four fingers (as in a fingerless glove, but not the thumb) and an additional compartment encapsulating the four fingers. This compartment can be lifted off the fingers and folded back to allow the individual fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Condom
A condom is a sheath-shaped barrier device used during sexual intercourse to reduce the probability of pregnancy or a sexually transmitted infection (STI). There are both male and female condoms. With proper use—and use at every act of intercourse—women whose partners use male condoms experience a 2% per-year pregnancy rate. With typical use the rate of pregnancy is 18% per-year. Their use greatly decreases the risk of gonorrhea, chlamydia, trichomoniasis, hepatitis B, and HIV/AIDS. To a lesser extent, they also protect against genital herpes, human papillomavirus (HPV), and syphilis. The male condom is rolled onto an erect penis before intercourse and works by forming a physical barrier which blocks semen from entering the body of a sexual partner. Male condoms are typically made from latex and, less commonly, from polyurethane, polyisoprene, or lamb intestine. Male condoms have the advantages of ease of use, ease of access, and few side effects. Individuals with late ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoclonal Antibody
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes. It is possible to produce monoclonal antibodies that specifically bind to virtually any suitable substance; they can then serve to detect or purify it. This capability has become an investigative tool in biochemistry, molecular biology, and medicine. Monoclonal antibodies are being used on a clinical level for both the diagnosis and therapy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Immunoassay s (RIAs)
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An enzyme immunoassay is any of several immunoassay methods that use an enzyme bound to an antigen or antibody. These may include: * Enzyme-linked immunosorbent assay (ELISA) * Enzyme multiplied immunoassay technique (EMIT) * Fluorescent enzyme immunoassays (FEIAs) * Chemiluminescent immunoassays (CLIAs) * Radioimmunoassay A radioimmunoassay (RIA) is an immunoassay that uses radiolabeled molecules in a stepwise formation of immune complexes. A RIA is a very sensitive in vitro assay technique used to measure concentrations of substances, usually measuring antigen conc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quattromed
Quattromed Ltd is one of the leading biotechnology companies in Estonia providing medical diagnostics services and performing custom research programs for the biopharmaceutical industry. As of March 2009, Icosagen AS is the new business name of the former Quattromed Ltd. Profile Quattromed was established in 1999 as a spin-off from Tartu University.Estonian Biotechnology Association''. Retrieved 18. June 2007. It is based in Tartu, Estonia. Employing 80 full-time employees, it has grown into the largest biotechnology company in Estonia. Quattromed started with offering molecular diagnostic services, the activities today cover molecular and clinical diagnosticsQuattromed HTI Laboratories, life science productsQuattromed, latex allergen testin(Quattromed Ltd)and protein productionQuattromed Cell Factory. Products and services Quattromed’s activities are divided into three branches: medical diagnostics division, technology development division and life science products division. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Latex Allergy
Latex allergy is a medical term encompassing a range of allergic reactions to the proteins present in natural rubber latex. It generally develops after repeated exposure to products containing natural rubber latex. When latex-containing medical devices or supplies come in contact with mucous membranes, the membranes may absorb latex proteins. In some susceptible people, the immune system produces antibodies that react immunologically with these antigenic proteins. Many items contain or are made from natural rubber, including shoe soles, pen grips, hot water bottles, elastic bands, rubber gloves, condoms, baby-bottle nipples, and balloons; consequently, there are many possible routes of exposure that may trigger a reaction. People with latex allergies may also have or develop allergic reactions to some fruits, such as bananas. Signs and symptoms Allergic reactions to latex range from Type I hypersensitivity, the most serious form of reaction, to Type IV hypersensitivity. Rate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoclonal Antibodies
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies can have monovalent affinity, binding only to the same epitope (the part of an antigen that is recognized by the antibody). In contrast, polyclonal antibodies bind to multiple epitopes and are usually made by several different antibody-secreting plasma cell lineages. Bispecific monoclonal antibodies can also be engineered, by increasing the therapeutic targets of one monoclonal antibody to two epitopes. It is possible to produce monoclonal antibodies that specifically bind to virtually any suitable substance; they can then serve to detect or purify it. This capability has become an investigative tool in biochemistry, molecular biology, and medicine. Monoclonal antibodies are being used on a clinical level for both the diagnosis and therapy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allergology
Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, coughing, a runny nose, shortness of breath, or swelling. Note: food intolerances and food poisoning are separate conditions. Common allergens include pollen and certain foods. Metals and other substances may also cause such problems. Food, insect stings, and medications are common causes of severe reactions. Their development is due to both genetic and environmental factors. The underlying mechanism involves immunoglobulin E antibodies (IgE), part of the body's immune system, binding to an allergen and then to a receptor on mast cells or basophils where it triggers the release of inflammatory chemicals such as histamine. Diagnosis is t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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