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Lateral Intraparietal Cortex
The lateral intraparietal cortex (area LIP) is found in the intraparietal sulcus of the brain. This area is most likely involved in eye movement, as electrical stimulation evokes saccades (quick movements) of the eyes. It is also thought to contribute to working memory associated with guiding eye movement, examined using a delayed saccade task described below:Pesaran, B., Pezaris, J. S., Sahani, M., Mitra, P. P., & Andersen, R. A. (2002). Temporal structure in neuronal activity during working memory in macaque parietal cortex. Nature neuroscience, 5(8), 805-811. #A subject focuses on a fixation point at the center of a computer screen. #A target (for instance a shape) is presented at a peripheral location on the screen. #The target is removed and followed by a variable-length delay period. #The initial focus point in the middle of the screen is removed. #The subject's task is to make a saccade to the location of the target. Neurons in area LIP have been shown to start responding ...
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Intraparietal Sulcus
The intraparietal sulcus (IPS) is located on the lateral surface of the parietal lobe, and consists of an oblique and a horizontal portion. The IPS contains a series of functionally distinct subregions that have been intensively investigated using both single cell neurophysiology in primates and human functional neuroimaging. Its principal functions are related to perceptual-motor coordination (e.g., directing eye movements and reaching) and visual attention, which allows for visually-guided pointing, grasping, and object manipulation that can produce a desired effect. The IPS is also thought to play a role in other functions, including processing symbolic numerical information, visuospatial working memory and interpreting the intent of others. Function Five regions of the intraparietal sulcus (IPS): anterior, lateral, ventral, caudal, and medial * LIP & VIP: involved in visual attention and saccadic eye movements * VIP & MIP: visual control of reaching and pointing * AIP: visu ...
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Lippincott Williams & Wilkins
Lippincott Williams & Wilkins (LWW) is an American imprint of the American Dutch publishing conglomerate Wolters Kluwer. It was established by the acquisition of Williams & Wilkins and its merger with J.B. Lippincott Company in 1998. Under the LWW brand, Wolters Kluwer, through its Health Division, publishes scientific, technical, and medical content such as textbooks, reference works, and over 275 scientific journals (most of which are medical or other public health journals). Publications are aimed at physicians, nurses, clinicians, and students. Overview LWW grew out of the gradual consolidation of various earlier independent publishers by Wolters Kluwer. Predecessor Wolters Samson acquired Raven Press of New York in 1986. Wolters Samson merged with Kluwer in 1987. The merged company bought J. B. Lippincott & Co. of Philadelphia in 1990; it merged Lippincott with the Raven Press to form Lippincott-Raven in 1995. In 1997 and 1998, Wolters Kluwer acquired Thomson Science (owner ...
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Saccade
A saccade ( , French for ''jerk'') is a quick, simultaneous movement of both eyes between two or more phases of fixation in the same direction.Cassin, B. and Solomon, S. ''Dictionary of Eye Terminology''. Gainesville, Florida: Triad Publishing Company, 1990. In contrast, in smooth pursuit movements, the eyes move smoothly instead of in jumps. The phenomenon can be associated with a shift in frequency of an emitted signal or a movement of a body part or device. Controlled cortically by the frontal eye fields (FEF), or subcortically by the superior colliculus, saccades serve as a mechanism for fixation, rapid eye movement, and the fast phase of optokinetic nystagmus. The word appears to have been coined in the 1880s by French ophthalmologist Émile Javal, who used a mirror on one side of a page to observe eye movement in silent reading, and found that it involves a succession of discontinuous individual movements. Function Humans and many animals do not look at a scene in f ...
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Working Memory
Working memory is a cognitive system with a limited capacity that can hold information temporarily. It is important for reasoning and the guidance of decision-making and behavior. Working memory is often used synonymously with short-term memory, but some theorists consider the two forms of memory distinct, assuming that working memory allows for the manipulation of stored information, whereas short-term memory only refers to the short-term storage of information. Working memory is a theoretical concept central to cognitive psychology, neuropsychology, and neuroscience. History The term "working memory" was coined by Miller, Galanter, and Pribram, and was used in the 1960s in the context of theories that likened the mind to a computer. In 1968, Atkinson and Shiffrin used the term to describe their "short-term store". What we now call working memory was formerly referred to variously as a "short-term store" or short-term memory, primary memory, immediate memory, operant memo ...
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Two-alternative Forced Choice
Two-alternative forced choice (2AFC) is a method for measuring the sensitivity of a person, child or infant, or animal to some particular sensory input, stimulus, through that observer's pattern of choices and response times to two versions of the sensory input. For example, to determine a person's sensitivity to dim light, the observer would be presented with a series of trials in which a dim light was randomly either in the top or bottom of the display. After each trial, the observer responds "top" or "bottom". The observer is not allowed to say "I do not know", or "I am not sure", or "I did not see anything". In that sense the observer's choice is forced between the two alternatives. Both options can be presented concurrently (as in the above example) or sequentially in two intervals (also known as two-interval forced choice, 2IFC). For example, to determine sensisitivity to a dim light in a two-interval forced choice procedure, an observer could be presented with series of trials ...
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Sensory Modality
Stimulus modality, also called sensory modality, is one aspect of a stimulus or what is perceived after a stimulus. For example, the temperature modality is registered after heat or cold stimulate a receptor. Some sensory modalities include: light, sound, temperature, taste, pressure, and smell. The type and location of the sensory receptor activated by the stimulus plays the primary role in coding the sensation. All sensory modalities work together to heighten stimuli sensation when necessary. Multimodal perception Multimodal perception is the ability of the mammalian nervous system to combine all of the different inputs of the sensory nervous system to result in an enhanced detection or identification of a particular stimulus. Combinations of all sensory modalities are done in cases where a single sensory modality results in ambiguous and incomplete result. Integration of all sensory modalities occurs when multimodal neurons receive sensory information which overlaps with di ...
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Memory
Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed. It is the retention of information over time for the purpose of influencing future action. If past events could not be remembered, it would be impossible for language, relationships, or personal identity to develop. Memory loss is usually described as forgetfulness or amnesia. Memory is often understood as an informational processing system with explicit and implicit functioning that is made up of a sensory processor, short-term (or working) memory, and long-term memory. This can be related to the neuron. The sensory processor allows information from the outside world to be sensed in the form of chemical and physical stimuli and attended to various levels of focus and intent. Working memory serves as an encoding and retrieval processor. Information in the form of stimuli is encoded in accordance with explicit or implicit functions by the working memory processor. ...
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