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Luteolytic
Luteolysis (also known as luteal regression) is the structural and functional degradation of the corpus luteum, which occurs at the end of the luteal phase of both the estrous and menstrual cycles in the absence of pregnancy. Prostaglandin F2 alpha (PGF2α) Prostaglandin F2 alpha (PGF2α) has been identified as the key luteolytic hormone in many species. PGF2α is released from uterine endometrial cells in a pulsatile pattern when stimulated by oxytocin to stimulate both luteolytic activity and further release of oxytocin from the corpus luteum. Domestic animals In domestic animals, luteolysis is initiated by the hormones prostaglandin F2alpha and oxytocin and is dependent on the presence of the uterus. In sheep, communication between the pars nervosa (posterior lobe of the pituitary gland), corpus luteum, and the uterus endometrium via the circulatory system is required for luteolysis. Studies with sheep have found that, if the uterine horn is ipsilateral to the ovary possessin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corpus Luteum
The corpus luteum (Latin for "yellow body"; plural corpora lutea) is a temporary endocrine structure in female ovaries involved in the production of relatively high levels of progesterone, and moderate levels of estradiol, and inhibin A. It is the remains of the ovarian follicle that has released a mature ovum during a previous ovulation. The corpus luteum is colored as a result of concentrating carotenoids (including lutein) from the diet and secretes a moderate amount of estrogen that inhibits further release of gonadotropin-releasing hormone (GnRH) and thus secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). A new corpus luteum develops with each menstrual cycle. Development and structure The corpus luteum develops from an ovarian follicle during the luteal phase of the menstrual cycle or oestrous cycle, following the release of a secondary oocyte from the follicle during ovulation. The follicle first forms a corpus hemorrhagicum before it becomes a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
