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Lovelace Respiratory Research Institute
Lovelace Biomedical Research Institute is a private contract research organization that is part of Touro University and New York Medical College (NYMC). It was founded after WWII in Albuquerque, New Mexico by two physicians, William Randolph Lovelace I and his nephew, surgeon William Randolph Lovelace II. LRRI originally performed not-for-profit biomedical research into the prevention, treatment and cure of respiratory disease. The organization expanded with military grants into the research and development of CBRNe, setting up a lab inside Kirtland Air Force Base, preclinical contract research for drug development, clinical trials and in 1998, the study of mental illness by providing neuroimaging and big data analysis with machine learning. The U.S. Department of Agriculture (USDA) found LRRI violated the Animal Welfare Act on multiple occasions since 2008. In 2018, its name appeared in the European dieselgate scandal, as it had tested the health effect of diesel exhaust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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Lovelace Biomedical Research Institute is a private contract research organization that is part of Touro University and New York Medical College (NYMC). It was founded after WWII in Albuquerque, New Mexico by two physicians, William Randolph Lovelace I and his nephew, surgeon William Randolph Lovelace II. LRRI originally performed not-for-profit biomedical research into the prevention, treatment and cure of respiratory disease. The organization expanded with military grants into the research and development of CBRNe, setting up a lab inside Kirtland Air Force Base, preclinical contract research for drug development, clinical trials and in 1998, the study of mental illness by providing neuroimaging and big data analysis with machine learning. The U.S. Department of Agriculture (USDA) found LRRI violated the Animal Welfare Act on multiple occasions since 2008. In 2018, its name appeared in the European dieselgate scandal, as it had tested the health effect of diesel exhaust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research And Development
Research and development (R&D or R+D), known in Europe as research and technological development (RTD), is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existing ones. Research and development constitutes the first stage of development of a potential new service or the production process. R&D activities differ from institution to institution, with two primary models of an R&D department either staffed by engineers and tasked with directly developing new products, or staffed with industrial scientists and tasked with applied research in scientific or technological fields, which may facilitate future product development. R&D differs from the vast majority of corporate activities in that it is not intended to yield immediate profit, and generally carries greater risk and an uncertain return on investment. However R&D is crucial for acquiring larger shares of the market through the marketisation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bronchitis
Bronchitis is inflammation of the bronchi (large and medium-sized airways) in the lungs that causes coughing. Bronchitis usually begins as an infection in the nose, ears, throat, or sinuses. The infection then makes its way down to the bronchi. Symptoms include coughing up sputum, wheezing, shortness of breath, and chest pain. Bronchitis can be acute or chronic. Acute bronchitis usually has a cough that lasts around three weeks, and is also known as a chest cold. In more than 90% of cases the cause is a viral infection. These viruses may be spread through the air when people cough or by direct contact. A small number of cases are caused by a bacterial infection such as ''Mycoplasma pneumoniae'' or ''Bordetella pertussis''. Risk factors include exposure to tobacco smoke, dust, and other air pollution. Treatment of acute bronchitis typically involves rest, paracetamol (acetaminophen), and nonsteroidal anti-inflammatory drugs (NSAIDs) to help with the fever. Chronic bronchi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lung Cancer
Lung cancer, also known as lung carcinoma (since about 98–99% of all lung cancers are carcinomas), is a malignant lung tumor characterized by uncontrolled cell growth in tissue (biology), tissues of the lung. Lung carcinomas derive from transformed, malignant cells that originate as epithelial cells, or from tissues composed of epithelial cells. Other lung cancers, such as the rare sarcomas of the lung, are generated by the malignant transformation of connective tissues (i.e. nerve, fat, muscle, bone), which arise from mesenchymal cells. Lymphomas and melanomas (from lymphoid and melanocyte cell lineages) can also rarely result in lung cancer. In time, this uncontrolled neoplasm, growth can metastasis, metastasize (spreading beyond the lung) either by direct extension, by entering the lymphatic circulation, or via hematogenous, bloodborne spread – into nearby tissue or other, more distant parts of the body. Most cancers that originate from within the lungs, known as primary ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emphysema
Emphysema, or pulmonary emphysema, is a lower respiratory tract disease, characterised by air-filled spaces ( pneumatoses) in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the walls of the alveoli and they replace the spongy lung parenchyma. This reduces the total alveolar surface available for gas exchange leading to a reduction in oxygen supply for the blood. Emphysema usually affects the middle aged or older population because it takes time to develop with the effects of tobacco smoking, and other risk factors. Alpha-1 antitrypsin deficiency is a genetic risk factor that may lead to the condition presenting earlier. When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asthma
Asthma is a long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diagnosis is usually based on the pattern of symptoms, response to therapy over time, and spirometry lung function testing. Asthma is classified according to the frequency of symptoms, forced expiratory volume in one second (FEV1), and peak expiratory flow rate. It may also be classified as atopic or non-atopic, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Defeat Device
A defeat device is any motor vehicle hardware, software, or design that interferes with or disables emissions controls under real-world driving conditions, even if the vehicle passes formal emissions testing.United States Code of Federal Regulations: * * * European emission standards: FAQ – Air pollutant emissions standards ''European Commission'', 25 September 2015. Quote: Article 5 (2) of Euro 6 Regulation 715/2007/EC prohibits the use of defeat devices. Article 3(10) defines defeat device as any element of design which senses temperature, vehicle speed, engine speed (RPM), transmission gear, manifold vacuum or any other parameter for the purpose of activating, modulating, delaying or deactivating the operation of any part of the emission control system, that reduces the effectiveness of the emission control system under conditions which may reasonably be expected to be encountered in normal vehicle operation and use. REGULATION (EC) No 715/2007 OF THE EUROPEAN PARLIAMENT ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diesel Exhaust
Diesel exhaust is the gaseous exhaust produced by a diesel type of internal combustion engine, plus any contained particulates. Its composition may vary with the fuel type or rate of consumption, or speed of engine operation (e.g., idling or at speed or under load), and whether the engine is in an on-road vehicle, farm vehicle, locomotive, marine vessel, or stationary generator or other application. Diesel exhaust is a Group 1 carcinogen, which causes lung cancer and has a positive association with bladder cancer. It contains several substances that are also listed individually as human carcinogens by the IARC. Methods exist to reduce nitrogen oxides (NOx) and particulate matter (PM) in the exhaust. So, while diesel fuel contains slightly more carbon (2.68 kg CO₂/litre) than petrol (2.31 kg CO₂/litre), overall CO₂ emissions of a diesel car tend to be lower due to higher efficiency. In use, on average, this equates to around 200 g CO₂/km for petrol and 120 g CO ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dieselgate
The Volkswagen emissions scandal, sometimes known as Dieselgate or Emissionsgate, began in September 2015, when the United States Environmental Protection Agency (EPA) issued a notice of violation of the Clean Air Act to German automaker Volkswagen Group. The agency had found that Volkswagen had intentionally programmed turbocharged direct injection (TDI) diesel engines to activate their emissions controls only during laboratory emissions testing, which caused the vehicles' output to meet US standards during regulatory testing. However, the vehicles emitted up to 40 times more in real-world driving. Volkswagen deployed this software in about 11 million cars worldwide, including 500,000 in the United States, in model years 2009 through 2015. Background Introduction In 2014, the California Air Resources Board (CARB) commissioned a study from the International Council on Clean Transportation (ICCT) on emissions discrepancies between European and US models of vehicles, s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Animal Welfare Act Of 1966
The Animal Welfare Act (Laboratory Animal Welfare Act of 1966, ) was signed into law by President Lyndon B. Johnson on August 24, 1966. It is the main federal law in the United States that regulates the treatment of animals in research and exhibition. Other laws, policies, and guidelines may include additional species coverage or specifications for animal care and use, but all refer to the Animal Welfare Act (otherwise known as the "AWA") as the minimally acceptable standard for animal treatment and care. The USDA and APHIS oversee the AWA and the House and Senate Agriculture Committees have primary legislative jurisdiction over the Act. Animals covered under this Act include any live or dead cat, dog, hamster, rabbit, nonhuman primate, guinea pig, and any other warm-blooded animal determined by the Secretary of Agriculture for research, pet use or exhibition. Excluded from the Act are birds, rats of the genus ''Rattus'' (laboratory rats), mice of the genus ''Mus'' (laboratory mic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Machine Learning
Machine learning (ML) is a field of inquiry devoted to understanding and building methods that 'learn', that is, methods that leverage data to improve performance on some set of tasks. It is seen as a part of artificial intelligence. Machine learning algorithms build a model based on sample data, known as training data, in order to make predictions or decisions without being explicitly programmed to do so. Machine learning algorithms are used in a wide variety of applications, such as in medicine, email filtering, speech recognition, agriculture, and computer vision, where it is difficult or unfeasible to develop conventional algorithms to perform the needed tasks.Hu, J.; Niu, H.; Carrasco, J.; Lennox, B.; Arvin, F.,Voronoi-Based Multi-Robot Autonomous Exploration in Unknown Environments via Deep Reinforcement Learning IEEE Transactions on Vehicular Technology, 2020. A subset of machine learning is closely related to computational statistics, which focuses on making predicti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Big Data Analysis
Though used sometimes loosely partly because of a lack of formal definition, the interpretation that seems to best describe Big data is the one associated with large body of information that we could not comprehend when used only in smaller amounts. In it primary definition though, Big data refers to data sets that are too large or complex to be dealt with by traditional data-processing application software. Data with many fields (rows) offer greater statistical power, while data with higher complexity (more attributes or columns) may lead to a higher false discovery rate. Big data analysis challenges include capturing data, data storage, data analysis, search, sharing, transfer, visualization, querying, updating, information privacy, and data source. Big data was originally associated with three key concepts: ''volume'', ''variety'', and ''velocity''. The analysis of big data presents challenges in sampling, and thus previously allowing for only observations and sampling. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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