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Loa Loa
''Loa loa'' is a filarial (arthropod-borne) nematode (roundworm) that causes ''Loa loa'' filariasis. ''Loa loa'' actually means "worm worm", but is commonly known as the "eye worm", as it localizes to the conjunctiva of the eye. ''Loa loa'' is commonly found in Africa.Schmidt, Gerald et al. "Foundations of Parasitology". 7th ed. McGraw Hill, New York, NY, 2005. It mainly inhabits rain forests in West Africa and has native origins in Ethiopia. The disease caused by ''Loa loa'' is called loiasis and is one of the neglected tropical diseases. ''L. loa'' is one of three parasitic filarial nematodes that cause subcutaneous filariasis in humans. The other two are ''Mansonella streptocerca and Onchocerca volvulus'' (causes river blindness). Maturing larvae and adults of the "eye worm" occupy the subcutaneous layer of the skin – the fat layer – of humans, causing disease. The ''L. loa'' adult worm which travels under the skin can survive up to 10–15 years, causing inflammati ...
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Microfilaria
::''Microfilaria may also refer to an informal "collective group" genus name, proposed by Cobbold in 1882. While a convenient category for newly discovered microfilariae which can not be assigned to a known species because the adults are unknown, it is seldom used today.'' The microfilaria (plural microfilariae, sometimes abbreviated mf) is an early stage in the life cycle of certain parasitic nematodes in the family Onchocercidae. In these species, the adults live in a tissue or the circulatory system of vertebrates (the "definitive hosts"). They release microfilariae into the bloodstream of the vertebrate host. The microfilariae are taken up by blood-feeding arthropod vectors (the "intermediate hosts"). In the intermediate host the microfilariae develop into infective larvae that can be transmitted to a new vertebrate host. The presence of microfilariae in the host bloodstream is called "microfilaraemia". The success of filariasis eradication programs is typically gauged by ...
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Horse-fly
Horse-flies or horseflies are true Fly, flies in the family Tabanidae in the insect Order (biology), order Diptera. They are often large and agile in flight, and only the female horseflies bite animals, including humans, to hematophagy, obtain blood. They prefer to fly in sunlight, avoiding dark and shady areas, and are inactive at night. They are found all over the world except for some islands and the polar regions (Hawaii, Greenland, Iceland). Both horse-flies and Botfly, botflies (Oestridae) are sometimes referred to as gadflies. Adult horse-flies feed on nectar and plant exudates; the males have weak insect mouthparts, mouthparts and only the females bite animals to obtain enough protein from blood to produce eggs. The mouthparts of females are formed into a stout stabbing organ with two pairs of sharp cutting blades, and a spongelike part used to lap up the blood that flows from the wound. The larvae are Predation, predaceous and grow in semiaquatic habitats. Female hor ...
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Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) " isotype") that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing four Ig-like constant domains (Cε1–Cε4). IgE is thought to be an important part of the immune response against infection by certain parasitic worms, including ''Schistosoma mansoni'', ''Trichinella spiralis'', and ''Fasciola hepatica''. IgE is also utilized during immune defense against certain protozoan parasites such as ''Plasmodium falciparum''. IgE may have evolved as a defense to protect against venoms. IgE also has an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, most types of sinusitis, allergic rhinitis, food allergies, and specific types of chronic urticaria and atopic dermatitis. IgE also plays a pivotal role in responses to allergens, such as ...
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Eosinophil
Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells (WBCs) and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. They form about 2 to 3% of WBCs. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such ...
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Cyst
A cyst is a closed sac, having a distinct envelope and cell division, division compared with the nearby Biological tissue, tissue. Hence, it is a cluster of Cell (biology), cells that have grouped together to form a sac (like the manner in which water molecules group together to form a bubble); however, the distinguishing aspect of a cyst is that the cells forming the "shell" of such a sac are distinctly abnormal (in both appearance and behaviour) when compared with all surrounding cells for that given location. A cyst may contain air, fluids, or semi-solid material. A collection of pus is called an abscess, not a cyst. Once formed, a cyst may resolve on its own. When a cyst fails to resolve, it may need to be removed surgically, but that would depend upon its type and location. Cancer-related cysts are formed as a defense mechanism for the body following the development of mutations that lead to an uncontrolled cellular division. Once that mutation has occurred, the affected cell ...
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Diurnal Cycle
A diurnal cycle (or diel cycle) is any pattern that recurs every 24 hours as a result of one full rotation of the planet Earth around its axis. Earth's rotation causes surface temperature fluctuations throughout the day and night, as well as weather changes throughout the year. The diurnal cycle depends mainly on incoming solar radiation. Climate and atmosphere In climatology, the diurnal cycle is one of the most basic forms of climate patterns, including variations in diurnal temperature and rainfall. Diurnal cycles may be approximately sinusoidal or include components of a truncated sinusoid (due to the Sun's rising and setting) and thermal relaxation ( Newton cooling) at night. The diurnal cycle also has a great impact on carbon dioxide levels in the atmosphere, due to processes such as photosynthesis and cellular respiration. Biological effects Diurnal cycles of light and temperature can result in similar cycles in biological processes, such as photosynthesis i ...
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Hemolymph
Hemolymph, or haemolymph, is a fluid, analogous to the blood in vertebrates, that circulates in the interior of the arthropod (invertebrate) body, remaining in direct contact with the animal's tissues. It is composed of a fluid plasma in which hemolymph cells called hemocytes are suspended. In addition to hemocytes, the plasma also contains many chemicals. It is the major tissue type of the open circulatory system characteristic of arthropods (e.g. arachnids, crustaceans and insects). In addition, some non-arthropods such as molluscs possess a hemolymphatic circulatory system. Oxygen-transport systems were long thought unnecessary in insects, but ancestral and functional hemocyanin has been found in the hemolymph. Insect "blood" generally does not carry hemoglobin, although hemoglobin may be present in the tracheal system instead and play some role in respiration. Method of transport In the grasshopper, the closed portion of the system consists of tubular hearts and an aort ...
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Circulatory System
The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek ''kardia'' meaning ''heart'', and from Latin ''vascula'' meaning ''vessels''). The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms ''cardiovascular system'' and ''vascular system'' interchangeably with the ''circulatory system''. The network of blood vessels are the great vessels of the heart including large elastic arteries, and large veins; other arteries, smaller arterioles, capillaries that join with venules (small veins), and other veins. The Closed circulatory system, circulatory system is closed in vertebrates, which means that the blood never leaves the network of blood vessels. Some in ...
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Filarioidea
The Filarioidea are a Taxonomic rank, superfamily of highly Generalist and specialist species, specialised Parasitism, parasitic nematodes. Species within this superfamily are known as filarial worms or filariae (singular filaria). Infections with parasitic filarial worms cause disease conditions generically known as filariasis. Drugs against these worms are known as filaricides. Introduction Filarioidea all are Generalist and specialist species, specialised parasites and the Host (biology), definitive host is always a vertebrate, a mammal, bird, reptile or amphibian, but ''not'' a fish. The Host (biology), intermediate host is always an arthropod. Most of Filarioidea parasitise wild species, birds in particular, but some, especially in the family Onchocercidae, attack mammals, including humans and some domestic animals. Conditions that result from parasitism by Onchocercidae include some of the most troublesome diseases of the warmer regions, including Onchocerciasis, river blin ...
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Host (biology)
In biology and medicine, a host is a larger organism that harbours a smaller organism; whether a parasite, parasitic, a mutualism (biology), mutualistic, or a commensalism, commensalist ''guest'' (symbiont). The guest is typically provided with nourishment and shelter. Examples include animals playing host to parasitic worms (e.g. nematodes), cell (biology), cells harbouring pathogenic (disease-causing) viruses, a Fabaceae, bean plant hosting mutualistic (helpful) Rhizobia, nitrogen-fixing bacteria. More specifically in botany, a host plant supplies nutrient, food resources to micropredators, which have an evolutionarily stable strategy, evolutionarily stable relationship with their hosts similar to ectoparasitism. The host range is the collection of hosts that an organism can use as a partner. Symbiosis Symbiosis spans a wide variety of possible relationships between organisms, differing in their permanence and their effects on the two parties. If one of the partners in an ass ...
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Loa Loa
''Loa loa'' is a filarial (arthropod-borne) nematode (roundworm) that causes ''Loa loa'' filariasis. ''Loa loa'' actually means "worm worm", but is commonly known as the "eye worm", as it localizes to the conjunctiva of the eye. ''Loa loa'' is commonly found in Africa.Schmidt, Gerald et al. "Foundations of Parasitology". 7th ed. McGraw Hill, New York, NY, 2005. It mainly inhabits rain forests in West Africa and has native origins in Ethiopia. The disease caused by ''Loa loa'' is called loiasis and is one of the neglected tropical diseases. ''L. loa'' is one of three parasitic filarial nematodes that cause subcutaneous filariasis in humans. The other two are ''Mansonella streptocerca and Onchocerca volvulus'' (causes river blindness). Maturing larvae and adults of the "eye worm" occupy the subcutaneous layer of the skin – the fat layer – of humans, causing disease. The ''L. loa'' adult worm which travels under the skin can survive up to 10–15 years, causing inflammati ...
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Chrysops Silacea
Deer flies (also known in some parts of the mid-Atlantic United States as sheep flies) are bloodsucking insects considered pests to humans and cattle. They are large flies with large brightly-coloured compound eyes, and large clear wings with dark bands. They are larger than the common housefly and smaller than the horse-fly. There are 250 species of deer fly in the genus ''Chrysops''. Their distribution is worldwide, though they have not been reported in Iceland, Greenland, and Hawaii. Deer flies lay between 100 and 800 eggs in batches on vegetation near water or dampness. During the larval stage, which lasts one to three weeks, they feed on small creatures or rotting organic matter near or in the water. After a pupal stage, they emerge as adults in late spring and summer. While male deer flies collect pollen, female deer flies feed on blood, which they require to produce eggs. Females feed primarily on mammals. They are attracted to prey by sight, smell, or the detection of car ...
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