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List Of Biophysicists
This is a list of notable people known for their research in biophysics. A * Gary Ackers (American, 1939–2011) — thermodynamics of protein assembly into complexes, protein-DNA interactions and enzyme subunit interactions * David Agard * Christian B. Anfinsen (American, 1916–1995) — author of the postulate about spontaneous protein folding, for which he received a Nobel Prize B * David Baker — Protein structure prediction; protein design; Rosetta software * Adriaan (Ad) Bax (Dutch-born American, 1956–) — development of methodology for NMR (Nuclear magnetic resonance) spectroscopy * Georg von Békésy (Hungarian, 1899–1972) — research on the human ear * Boris Pavlovich Belousov — known for discovery of Belousov–Zhabotinsky reaction * Howard Berg (American, 1934–2021) — characterized properties of bacterial chemotaxis * Helen M. Berman (American, 1943–) — pioneer in study of nucleic acid structure; ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and biochemistry. Overview ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Desmond Bernal
John Desmond Bernal (; 10 May 1901 – 15 September 1971) was an Irish scientist who pioneered the use of X-ray crystallography in molecular biology. He published extensively on the history of science. In addition, Bernal wrote popular books on science and society. He was a communist activist and a member of the Communist Party of Great Britain (CPGB). Education and early life His family was Irish, of mixed Spanish, Portuguese and Italian Sephardic origin on his father's side (his grandfather Jacob Genese, properly Ginesi, had adopted the family name Bernal of his paternal grandmother around 1837). His father Samuel Bernal had been raised as a Catholic in Limerick and after graduating from Albert Agricultural College spent 14 years in Australia before returning to Tipperary to buy a farm, ''Brookwatson'', near Nenagh where Bernal was brought up. His American mother, née Elizabeth Miller, whose mother was from Antrim, was a graduate of Stanford University and a journalist a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Detlev Wulf Bronk
Detlev Wulf Bronk (August 13, 1897 – November 17, 1975) was a prominent American scientist, educator, and administrator. He is credited with establishing biophysics as a recognized discipline. Bronk served as president of Johns Hopkins University from 1949 to 1953 and as president of The Rockefeller University from 1953 to 1968. Bronk also held the presidency of the United States National Academy of Sciences, National Academy of Sciences between 1950 and 1962. Biography Bronk was a descendant of Pieter Bronck, an early settler to New Netherland for whose relative Jonas Bronck the New York City borough The Bronx is named. Bronk graduated from Swarthmore with a B.S. in electrical engineering, where he was a member of Phi Kappa Psi, Phi Kappa Psi Fraternity. In September 1921 Bronk married Helen Alexander Ramsey, who had been a fellow student at Swarthmore. Turning to physics, he received an M.S. in 1922 from the University of Michigan. By 1924 he was intent on applying physics and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jagadish Chandra Bose
Sir Jagadish Chandra Bose (;, ; 30 November 1858 – 23 November 1937) was a biologist, physicist, Botany, botanist and an early writer of science fiction. He was a pioneer in the investigation of radio microwave optics, made significant contributions to botany, and was a major force behind the expansion of experimental science on the Indian subcontinent. Bose is considered the father of Bengali science fiction. He invented the crescograph, a device for measuring the growth of plants. Bose (crater), A crater on the moon was named in his honour. He founded Bose Institute, a premier research institute in India and also one of its oldest. Established in 1917, the institute was the first interdisciplinary research centre in Asia. He served as the Director of Bose Institute from its inception until his death. Born in Munshiganj, Bengal Presidency, during British India, British governance of India (now in Bangladesh), Bose graduated from St. Xavier's College, Calcutta (now Kolkata, W ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tom Blundell
Sir Thomas Leon Blundell, (born 7 July 1942) is a British biochemist, structural biologist, and science administrator. He was a member of the team of Dorothy Hodgkin that solved in 1969 the first structure of a protein hormone, insulin. Blundell has made contributions to the structural biology of polypeptide hormones, growth factors, receptor activation, signal transduction, and DNA double-strand break repair, subjects important in cancer, tuberculosis, and familial diseases. He has developed software for protein modelling and understanding the effects of mutations on protein function, leading to new approaches to structure-guided and Fragment-based lead discovery. In 1999 he co-founded the oncology company Astex Therapeutics, which has moved ten drugs into clinical trials. Blundell has played central roles in restructuring British research councils and, as President of the UK Science Council, in developing professionalism in the practice of science. Education Born in Bri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Optical Tweezers
Optical tweezers (originally called single-beam gradient force trap) are scientific instruments that use a highly focused laser beam to hold and move microscopic and sub-microscopic objects like atoms, nanoparticles and droplets, in a manner similar to tweezers. If the object is held in air or vacuum without additional support, it can be called optical levitation. The laser light provides an attractive or repulsive force (typically on the order of pico newtons), depending on the relative refractive index between particle and surrounding medium. Levitation is possible if the force of the light counters the force of gravity. The trapped particles are usually micron-sized, or even smaller. Dielectric and absorbing particles can be trapped, too. Optical tweezers are used in biology and medicine (for example to grab and hold a single bacterium, a cell like a sperm cell or a blood cell, or a molecule like DNA), nanoengineering and nanochemistry (to study and build materials from sing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA Polymerase
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that synthesizes RNA from a DNA template. Using the enzyme helicase, RNAP locally opens the double-stranded DNA so that one strand of the exposed nucleotides can be used as a template for the synthesis of RNA, a process called transcription. A transcription factor and its associated transcription mediator complex must be attached to a DNA binding site called a promoter region before RNAP can initiate the DNA unwinding at that position. RNAP not only initiates RNA transcription, it also guides the nucleotides into position, facilitates attachment and elongation, has intrinsic proofreading and replacement capabilities, and termination recognition capability. In eukaryotes, RNAP can build chains as long as 2.4 million nucleotides. RNAP produces RNA that, functionally, is either for protein coding, i.e. messenger RNA (mRNA); or n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kinesin
A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport, and intraflagellar transport. Most kinesins walk towards the plus end of a microtubule, which, in most cells, entails transporting cargo such as protein and membrane components from the center of the cell towards the periphery. This form of transport is known as anterograde transport. In contrast, dyneins are motor proteins that move toward the minus end of a microtubule in retrograde transport. Discovery Kinesins were discovered in 1985, based on their motility in cytoplasm extruded from the giant axon of the squid. They turned out as MT-based anterograde intracellular trans ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Steven Block
Steven M. Block (born 1952) is an American biophysicist and Professor at Stanford University with a joint appointment in the departments of Biology and Applied Physics. In addition, he is a member of the scientific advisory group JASON, a senior fellow of Stanford's Freeman Spogli Institute for International Studies, and an amateur bluegrass musician. Block received his B.A. and M.A. from Oxford University. He has been elected to the U.S. National Academy of Sciences (2007) and the American Academy of Arts and Sciences (2000), and is a winner of the Max Delbruck Prize of the American Physical Society (2008), as well as the Single Molecule Biophysics Prize of the Biophysical Society (2007). He served as President of the Biophysical Society during 2005-6. His graduate work was completed in the laboratory of Howard Berg at the University of Colorado and Caltech. He received his Ph.D. in 1983 and went on to do postdoctoral research at Stanford. Since that time, Block has held positio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Major Histocompatibility Complex
The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system. These cell surface proteins are called MHC molecules. This locus got its name because it was discovered via the study of transplanted tissue compatibility. Later studies revealed that tissue rejection due to incompatibility is only a facet of the full function of MHC molecules: binding an antigen derived from self-proteins, or from pathogens, and bringing the antigen presentation to the cell surface for recognition by the appropriate T-cells. MHC molecules mediate the interactions of leukocytes, also called white blood cells (WBCs), with other leukocytes or with body cells. The MHC determines donor compatibility for organ transplant, as well as one's susceptibility to autoimmune diseases. In a cell, protein molecules of the host's own phenotype or of other biologic entities ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histocompatibility
Histocompatibility, or tissue compatibility, is the property of having the same, or sufficiently similar, alleles of a set of genes called human leukocyte antigens (HLA), or major histocompatibility complex (MHC). Each individual expresses many unique HLA proteins on the surface of their cells, which signal to the immune system whether a cell is part of the self or an invading organism. T cells recognize foreign HLA molecules and trigger an immune response to destroy the foreign cells. Histocompatibility testing is most relevant for topics related to whole organ, tissue, or stem cell transplants, where the similarity or difference between the donor's HLA alleles and the recipient's triggers the immune system to reject the transplant. The wide variety of potential HLA alleles lead to unique combinations in individuals and make matching difficult. Discovery The discovery of the MHC and role of histocompatibility in transplantation was a combined effort of many scientists in the 20t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pamela J
Pamela may refer to: *''Pamela; or, Virtue Rewarded'', a novel written by Samuel Richardson in 1740 *Pamela (name), a given name and, rarely, a surname *Pamela Spence, a Turkish pop-rock singer. Known as her stage name "Pamela" * MSC ''Pamela'', a container ship launched in 2005 * ''Pamela'' (butterfly), a butterfly genus *''Perrhybris pamela'', a butterfly with the common name Pamela *Pamela hat, a straw hat named after Richardson's heroine, worn 1790s–1870s * ''Pamela'' (film), a 1945 French film * Super Typhoon Pamela, a typhoon in 1976 *''Una donna da guardare'', a 1990 Italian erotic movie *''P.A.M.E.L.A.'', a first-person survival video game Songs *"Pamela Pamela", a song recorded by Wayne Fontana that reached number 11 in the UK Singles Chart in 1967 * "Pamela" (song), a 1988 hit song for the band Toto *"Pamella", a song by Remmy Ongala from the album ''Songs For the Poor Man'' *"Pamela Wan", a song composed by Vhong Navarro in 2004, inspired by the movie Otso-Otso Pam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
