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Lipozyme
Lipozyme, a registered trademark of Novo Nordisk A/S Corp., is a class of industrial enzymes, specifically: lipases. Lipozymes can be differentiated by origin - it can be extracted from ''Mucor miehei'', '' Thermomyces lanuginosus'', ''Candida antarctica'', and others.https://www.novozymes.com/-/media/Project/Novozymes/Website/website/document-library/Advance-your-business/Pharma/Biocatalysis_brochure_Lipases.pdf https://www.sigmaaldrich.com/catalog/product/sigma/62350?lang=de®ion=DE For industrial purposes, it can be immobilized on macroporous ion-exchange resins. Lipases like Lipozyme and Novozyme (reg.trademark by Novozymes) play a big role in the synthesis of biodiesel. Lipozyme is also offered as a food supplement A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order ... clad in c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Industrial Enzymes
Industrial enzymes are enzymes that are commercially used in a variety of industries such as pharmaceuticals, chemical production, biofuels, food & beverage, and consumer products. Due to advancements in recent years, biocatalysis through isolated enzymes is considered more economical than use of whole cells. Enzymes may be used as a unit operation within a process to generate a desired product, or may be the product of interest. Industrial biological catalysis through enzymes has experienced rapid growth in recent years due to their ability to operate at mild conditions, and exceptional chiral and positional specificity, things that traditional chemical processes lack. Isolated enzymes are typically used in hydrolytic and isomerization reactions. Whole cells are typically used when a reaction requires a co-factor. Although co-factors may be generated in vitro, it is typically more cost-effective to use metabolically active cells. Enzymes as a unit of operation Immobilizatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novo Nordisk
Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in nine countries, and affiliates or offices in five countries. Novo Nordisk is controlled by majority shareholder Novo Holdings A/S which holds approximately 25% of its shares and a supermajority (45%) of its voting shares. Novo Nordisk manufactures and markets pharmaceutical products and services specifically diabetes care medications and devices. Novo Nordisk is also involved with hemostasis management, growth hormone therapy and hormone replacement therapy. The company makes several drugs under various brand names, including Levemir, Tresiba, NovoLog, Novolin R, NovoSeven, NovoEight and Victoza. Novo Nordisk employs more than 48,000 people globally, and markets its products in 168 countries. The corporation was created in 1989 through a merger of two Danish companies which date back to the 1920s. The Novo Nordisk logo is the Apis bull, one of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lipase
Lipase ( ) is a family of enzymes that catalyzes the hydrolysis of fats. Some lipases display broad substrate scope including esters of cholesterol, phospholipids, and of lipid-soluble vitamins and sphingomyelinases; however, these are usually treated separately from "conventional" lipases. Unlike esterases, which function in water, lipases "are activated only when adsorbed to an oil–water interface". Lipases perform essential roles in digestion, transport and processing of dietary lipids in most, if not all, organisms. Structure and catalytic mechanism Classically, lipases catalyse the hydrolysis of triglycerides: :triglyceride + H2O → fatty acid + diacylglycerol :diacylglycerol + H2O → fatty acid + monacylglycerol :monacylglycerol + H2O → fatty acid + glycerol Lipases are serine hydrolases, i.e. they function by transesterification generating an acyl serine intermediate. Most lipases act at a specific position on the glycerol backbone of a lipid sub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mucor Miehei
''Rhizomucor miehei'' (also: ''Mucor miehei'' ) is a species of fungus A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from t .... It is commercially used to produce enzymes which can be used to produce a microbial rennet to curd milk and produce cheese. Under experimental conditions, this species grows particularly well at temperatures between 24 and 55°C, and their growth becomes negligible below 21°C or above 57°C. It is also used to produce lipases for interesterification of fats. See also * Industrial enzymes References External links Index Fungorumlisting Fungi {{zygomycota-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thermomyces Lanuginosus
''Thermomyces lanuginosus'' is a species of thermophilic fungus that belongs to ''Thermomyces,'' a genus of hemicellulose degraders. It is classified as a deuteromycete and no sexual form has ever been observed. It is the dominant fungus of compost heaps, due to its ability to withstand high temperatures and use complex carbon sources for energy. As the temperature of compost heaps rises and the availability of simple carbon sources decreases, it is able to out compete pioneer microflora. It plays an important role in breaking down the hemicelluloses found in plant biomass due to the many hydrolytic enzymes that it produces, such as lipolase, amylase, xylanase, phytase, and chitinase. These enzymes have chemical, environmental, and industrial applications due to their hydrolytic properties. They are used in the food, petroleum, pulp and paper, and animal feed industries, among others. A few rare cases of endocarditis due to ''T. lanuginosus'' have been reported in humans. Histo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Candida Antarctica
''Candida antarctica'' is a yeast species in the genus '' Candida''. ''Candida antarctica'' is a source of important industrial enzymes. Immobilized ''Candida antarctica'' lipase can be used to catalyze the regioselective acylation of flavonoids or the direct acetylation with phenolic acids. This species contains a lipase enzyme that is able to cleave ester bonds in PET plastic. References External links antarctica Antarctica () is Earth's southernmost and least-populated continent. Situated almost entirely south of the Antarctic Circle and surrounded by the Southern Ocean, it contains the geographic South Pole. Antarctica is the fifth-largest cont ... Fungi described in 1983 {{ascomycota-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Immobilization
An immobilized enzyme is an enzyme, with restricted mobility, attached to an inert, insoluble material—such as calcium alginate (produced by reacting a mixture of sodium alginate solution and enzyme solution with calcium chloride). This can provide increased resistance to changes in conditions such as pH or temperature. It also lets enzymes be held in place throughout the reaction, following which they are easily separated from the products and may be used again - a far more efficient process and so is widely used in industry for enzyme catalysed reactions. An alternative to enzyme immobilization is whole cell immobilization. Immobilized enzymes are easily to be handled, simply separated from their products, and can be reused. Enzymes are bio-catalysts which play an essential role in the enhancement of chemical reactions in cells without being persistently modified, wasted, nor resulting in the loss of equilibrium of chemical reactions. Although the characteristics of enzymes are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novozymes
Novozymes A/S is a global biotechnology company headquartered in Bagsværd outside of Copenhagen, Denmark. The company's focus is the research, development and production of industrial enzymes, microorganisms, and biopharmaceutical ingredients. The company has operations around the world, including in China, India, Brazil, Argentina, United Kingdom, the United States, and Canada. Class B shares of its stock are listed on the NASDAQ OMX Nordic exchange. History In 1925 the brothers Harald and Thorvald Pedersen founded Novo Terapeutisk Laboratorium and Nordisk Insulinlaboratorium with the aim to produce insulin. In 1941 the company's predecessor launched its first enzyme, trypsin, extracted from the pancreas of animals and used to soften leather, and was the first to produce enzymes by fermentation using bacteria in the 1950s.NovozymeNovozymes' historyPage accessed August 31, 2014 In the late 1980s Novozymes presented the world's first fat-splitting enzyme for detergents ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biodiesel
Biodiesel is a form of diesel fuel derived from plants or animals and consisting of long-chain fatty acid esters. It is typically made by chemically reacting lipids such as animal fat (tallow), soybean oil, or some other vegetable oil with an alcohol, producing a methyl, ethyl or propyl ester by the process of transesterification. Unlike the vegetable and waste oils used to fuel converted diesel engines, biodiesel is a drop-in biofuel, meaning it is compatible with existing diesel engines and distribution infrastructure. However, it is usually blended with petrodiesel (typically to less than 10%) since most engines cannot run on pure Biodiesel without modification. Biodiesel blends can also be used as heating oil. The US National Biodiesel Board defines "biodiesel" as a mono-alkyl ester. Blends Blends of biodiesel and conventional hydrocarbon-based diesel are most commonly distributed for use in the retail diesel fuel marketplace. Much of the world uses a system know ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food Supplement
A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order to increase the quantity of their consumption. The class of nutrient compounds includes vitamins, minerals, fiber, fatty acids, and amino acids. Dietary supplements can also contain substances that have not been confirmed as being essential to life, but are marketed as having a beneficial biological effect, such as plant pigments or polyphenols. Animals can also be a source of supplement ingredients, such as collagen from chickens or fish for example. These are also sold individually and in combination, and may be combined with nutrient ingredients. The European Commission has also established harmonized rules to help insure that food supplements are safe and appropriately labeled. Creating an industry estimated to have a 2020 value of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme Activity
Enzyme assays are laboratory methods for measuring enzymatic activity. They are vital for the study of enzyme kinetics and enzyme inhibition. Enzyme units The quantity or concentration of an enzyme can be expressed in molar amounts, as with any other chemical, or in terms of activity in enzyme units. Enzyme activity Enzyme activity is a measure of the quantity of active enzyme present and is thus dependent on various physical conditions, ''which should be specified''. It is calculated using the following formula: :\operatorname=\operatorname=\operatorname\times\operatorname where :\operatorname= Enzyme activity :\operatorname= Moles of substrate converted per unit time :\operatorname= Rate of the reaction :\operatorname= Reaction volume The SI unit is the katal, 1 katal = 1 mol s−1 (mole per second), but this is an excessively large unit. A more practical and commonly used value is enzyme unit (U) = 1 μmol min−1 (micromole per minute). 1 U corresponds to 16.67 nano ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
