|
Lifespan Extension Advocacy Foundation
The Lifespan Extension Advocacy Foundation (LEAF) is a non-profit organization with mission to support fundamental research on the main mechanisms of aging and age-related diseases and educate the public on the possibility of bringing aging under medical control in order to prevent, postpone and cure age-related diseases. It was founded in 2014 and is based in New York City, New York, USA. Its activities include a news outlet covering aging research, an annual scientific conference on aging in New York City, and the nonprofit crowdfunding platform ''Lifespan.io''. As of 2020, the platform has hosted eight successful campaigns, including three research projects by SENS Research Foundation. News outlet LEAF established its news outlet in 2016 with the goal of educating the public on the progress in aging and longevity research. As of 2020, it contains over 900 news articles, including over 90 interviews with aging and rejuvenation researchers, such as Aubrey de Grey, Judith Camp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
501(c)
A 501(c) organization is a nonprofit organization in the Law of the United States#Federal law, federal law of the United States according to Internal Revenue Code (26 U.S.C. § 501(c)) and is one of over 29 types of nonprofit organizations exempt from some Taxation in the United States, federal Income tax in the United States, income taxes. Sections 503 through 505 set out the requirements for obtaining such exemptions. Many states refer to Section 501(c) for definitions of organizations exempt from state taxation as well. 501(c) organizations can receive unlimited contributions from individuals, corporations, and Labor union, unions. For example, a nonprofit organization may be tax-exempt under section 501(c)(3) organization, 501(c)(3) if its primary activities are charitable, religious, educational, scientific, literary, testing for public safety, fostering amateur sports competition, or preventing cruelty to Child abuse, children or Animal cruelty, animals. Types According ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jeanne Calment
Jeanne Louise Calment (; 21 February 1875 – 4 August 1997) was a French supercentenarian and the oldest human whose age is documented, with a lifespan of 122 years and 164 days. Her longevity attracted media attention and medical studies of her health and lifestyle. She is the only person verified to have lived to the age of 120 and beyond. According to census records, Calment outlived both her daughter and grandson. In January 1988, she was widely reported to have been the oldest living person, and in 1995, at age 120, was declared the oldest person to have lived. Early life Calment was born on 21 February 1875 in Arles, Bouches-du-Rhône, Provence. Some of her close family members also had an above-average lifespan as her older brother, François (1865–1962), lived to the age of 97, her father, Nicolas (1837–1931), who was a shipbuilder, 93, and her mother, Marguerite Gilles (1838–1924), who was from a family of millers, 86. From the age of seven until her ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rejuvenation Research
''Rejuvenation Research'' is a bimonthly peer-reviewed scientific journal published by Mary Ann Liebert that covers research on rejuvenation and biogerontology. The journal was established in 1998. The current acting editor-in-chief is Ben Zealley. It is the official journal of the European Society of Preventive, Regenerative and Anti-Aging Medicine as well as PYRAMED: World Federation and World Institute of Preventive & Regenerative Medicine. The journal exhibited unusual levels of self-citation and its journal impact factor of 2019 was suspended from ''Journal Citation Reports'' in 2020, a sanction which hit 33 journals in total. However, the journal's 2020 impact factor was made available again in June 2021. History The journal was established in 1998 as the ''Journal of Anti-Aging Medicine'' with Michael Fossel (Michigan State University) as editor-in-chief. It obtained its current title in 2004, when Aubrey de Grey took over as editor-in-chief. The current acting editor-in-ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maximum Life Span
Maximum life span (or, for humans, maximum reported age at death) is a measure of the maximum amount of time one or more members of a population have been observed to survive between birth and death. The term can also denote an estimate of the maximum amount of time that a member of a given species could survive between birth and death, provided circumstances that are optimal to that member's longevity. Most living species have an upper limit on the number of times somatic cells not expressing telomerase can divide. This is called the Hayflick limit, although this number of cell divisions does not strictly control lifespan. Definition In animal studies, maximum span is often taken to be the mean life span of the most long-lived 10% of a given cohort. By another definition, however, maximum life span corresponds to the age at which the oldest known member of a species or experimental group has died. Calculation of the maximum life span in the latter sense depends upon the i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immortality
Immortality is the concept of eternal life. Some modern species may possess biological immortality. Some scientists, futurists, and philosophers have theorized about the immortality of the human body, with some suggesting that human immortality may be achievable in the first few decades of the 21st century with the help of certain technologies such as mind uploading (digital immortality). Other advocates believe that life extension is a more achievable goal in the short term, with immortality awaiting further research breakthroughs. The absence of aging would provide humans with biological immortality, but not invulnerability to death by disease or injury. Whether the process of internal immortality is delivered within the upcoming years depends chiefly on research (and in neuron research in the case of internal immortality through an immortalized cell line) in the former view and perhaps is an awaited goal in the latter case. What form an unending human life would take, o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Geroprotector
A geroprotector is a senotherapeutic that aims to affect the root cause of aging and age-related diseases, and thus prolong the life span of animals. Some possible geroprotectors include melatonin, carnosine, metformin, rapamycin,nicotinamide mononucleotide Niacinamide or Nicotinamide (NAM) is a form of vitamin B3 found in food and used as a dietary supplement and medication. As a supplement, it is used by mouth to prevent and treat pellagra (niacin deficiency). While nicotinic acid (niacin) may ... (NMN) and delta sleep-inducing peptide. References External linksGeroprotectors A curated database of geroprotectors.Aging Chart A collection of community-curated pathways and knowledge related to aging. Ageing {{medicinal-chem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics Of Aging
Genetics of aging is generally concerned with life extension associated with genetic alterations, rather than with accelerated aging diseases leading to reduction in lifespan. The first mutation found to increase longevity in an animal was the '' age-1'' gene in '' Caenorhabditis elegans''. Michael Klass discovered that lifespan of ''C. elegans'' could be altered by mutations, but Klass believed that the effect was due to reduced food consumption (calorie restriction). Thomas Johnson later showed that life extension of up to 65% was due to the mutation itself rather than due to calorie restriction, and he named the gene ''age-1'' in the expectation that other genes that control aging would be found. The '' age-1'' gene encodes the catalytic subunit of class-I phosphatidylinositol 3-kinase (PI3K). A decade after Johnson's discovery ''daf-2'', one of the two genes that are essential for dauer larva formation, was shown by Cynthia Kenyon to double ''C. elegans'' l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eternal Youth
Eternal youth is the concept of human physical immortality free of ageing. The youth referred to is usually meant to be in contrast to the depredations of aging, rather than a specific age of the human lifespan. Eternal youth is common in mythology, and is a popular theme in fiction. Religion and mythology Eternal youth is a characteristic of the inhabitants of Paradise in Abrahamic religions. The Hindus believe that the Vedic and the post-Vedic rishis have attained immortality, which implies the ability to change one's body's age or even shape at will. These are some of the siddhas in Yoga. Markandeya is said to always stay at the age of 16. The difference between eternal life and the more specific eternal youth is a recurrent theme in Greek and Roman mythology. The mytheme of requesting the boon of immortality from a god, but forgetting to ask for eternal youth appears in the story of Tithonus. A similar theme is found in Ovid regarding the Cumaean Sibyl. In Norse myt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Immortality
Biological immortality (sometimes referred to as bio-indefinite mortality) is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age. Various unicellular and multicellular species, including some vertebrates, achieve this state either throughout their existence or after living long enough. A biologically immortal living being can still die from means other than senescence, such as through injury, poison, disease, predation, lack of available resources, or changes to environment. This definition of immortality has been challenged in the ''Handbook of the Biology of Aging'', because the increase in rate of mortality as a function of chronological age may be negligible at extremely old ages, an idea referred to as the late-life mortality plateau. The rate of mortality may cease to increase in old age, but in most cases that rate is typically very high. The term is also used by biologists to describe cells that are not ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CGP Grey
CGP Grey is an American-Irish educational YouTuber, podcaster, and live streamer who creates short explanatory videos on subjects including politics, geography, economics, sociology, history, and culture. In addition to video production, Grey is known for creating and hosting the podcasts ''Hello Internet'' with Brady Haran and ''Cortex'' with Myke Hurley. Early life Grey grew up in the Long Island suburbs of New York City. He went to college in upstate New York, earning two degrees: one in physics and another in sociology. When Grey was a child, his father applied for Irish citizenship on his behalf, and he gained dual American–Irish citizenship. Grey's Irish citizenship allowed him to move to the European Union and he moved to London. Grey attended a masters program in economics in London, and he continues to live in the city. Grey became a physics teacher while in London. Videos Grey's primary YouTube channel, ''CGP Grey'', predominantly features explanatory video ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kurzgesagt
Kurzgesagt (; German for "In a nutshell" or "in a few words") is a German-made animation and design studio founded by Philipp Dettmer. The studio's YouTube channel focuses on minimalist animated educational content, using the flat and 3D design style. It discusses scientific, technological, political, philosophical, and psychological subjects. Narrated by Steve Taylor, videos on the channel are typically four to sixteen minutes, with many of them available in German through the channel ''Dinge Erklärt – Kurzgesagt,'' their Spanish channel ''En Pocas Palabras - Kurzgesagt,'' and some of their videos are also available in French, Hindi, Arabic, Brazilian Portuguese, Japanese and Korean. With over 19 million subscribers and over 160 videos, the studio's original English language channel was ranked as the world's 198th most subscribed as of 8 November 2022. History The Kurzgesagt YouTube channel was created on 10 July 2013, shortly after the founder, Philipp Dettmer, graduate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Longevity
The word " longevity" is sometimes used as a synonym for "life expectancy" in demography. However, the term ''longevity'' is sometimes meant to refer only to especially long-lived members of a population, whereas ''life expectancy'' is always defined statistically as the average number of years remaining at a given age. For example, a population's life expectancy at birth is the same as the average age at death for all people born in the same year (in the case of cohorts). Longevity is best thought of as a term for general audiences meaning 'typical length of life' and specific statistical definitions should be clarified when necessary. Reflections on longevity have usually gone beyond acknowledging the brevity of human life and have included thinking about methods to extend life. Longevity has been a topic not only for the scientific community but also for writers of travel, science fiction, and utopia A utopia ( ) typically describes an imaginary community or society that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
.JPG "Click for more on -> Biological Immortality")
