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Leslie Z. Benet
Leslie 'Les' Zachary Benet (born May 17, 1937) is an influential pharmaceutical sciences, pharmaceutical scientist heading the University of California, San Francisco, UCSF's Benet Lab at the Department of Bioengineering and Therapeutic Sciences and recipient of the Remington Medal for distinguished service to American pharmacy. Early life and education Leslie Zachary Benet was born on May 17, 1937, in Cincinnati, Ohio, into a family of pharmacists. His father, Jonas and his uncle, Harry, opened Benet's Pharmacies in Cincinnati in the 1930s and in 1942 founded DARA Products, the first drug company to manufacture hypoallergenic dermatologicals. Benet received his B.A. (English, 1959), B.S. (Pharmacy, 1960), M.S. (Pharmaceutical Chemistry, 1962) from the University of Michigan and Ph.D. (Pharmaceutical Chemistry, 1965) from the University of California, San Francisco, University of California. Academic career Benet's early work included Pharmacokinetics#Noncompartmental analysis, no ...
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UCSF School Of Pharmacy
UCSF School of Pharmacy, is the pharmacy school of the University of California, San Francisco, and is located in San Francisco. Founded in 1872, it is the oldest pharmacy school in California and the western United States. For 41 consecutive years it has been the top recipient of NIH funding among all US pharmacy programs, with a total of $40.9 million in awards in 2020 (increasing almost $15 million from the previous year). In 2020, it was ranked second nationwide by U.S. News & World Report. History The school was founded in 1872 as the California College of Pharmacy by the California Pharmaceutical Society, itself then only four years old. At the time, the school became the first in the West and the tenth in the United States. The objectives of the founders were to “advance pharmaceutical knowledge and elevate the professional character of apothecaries throughout California.” On June 2, 1873, the college affiliates with the University of California, shortly after the Tola ...
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Biopharmaceutics Classification System
The Biopharmaceutics Classification System is a system to differentiate the drugs on the basis of their solubility and permeability. This system restricts the prediction using the parameters solubility and intestinal permeability. The solubility classification is based on a United States Pharmacopoeia (USP) aperture. The intestinal permeability classification is based on a comparison to the intravenous injection. All those factors are highly important because 85% of the most sold drugs in the United States and Europe are orally administered . BCS classes According to the Biopharmaceutical Classification System (BCS) drug substances are classified to four classes upon their solubility and permeability: *Class I - high permeability, high solubility ** Example: metoprolol, paracetamol ** Those compounds are well absorbed and their absorption rate is usually higher than excretion. *Class II - high permeability, low solubility ** Example: glibenclamide, bicalutamide, ezetim ...
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American Pharmacists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * Ba ...
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University Of Lisbon
The University of Lisbon (ULisboa; pt, Universidade de Lisboa, ) is a public research university in Lisbon, and the largest university in Portugal. It was founded in 2013, from the merger of two previous public universities located in Lisbon, the former University of Lisbon (1911–2013) and the Technical University of Lisbon (1930–2013). History The first Portuguese university was established in Lisbon between 1288 and 1290, when Dinis I promulgated the letter ''Scientiae thesaurus mirabili'', granting several privileges to the students of the ''studium generale'' in Lisbon, proving that it was already founded on that date. There was an active participation in this educational activity by the Portuguese Crown and its king, through its commitment of part of the subsidy of the same, as by the fixed incomes of the Church. This institution moved several times between Lisbon and Coimbra, where it settled permanently in 1537. The current University of Lisbon is the result of the ...
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International Pharmaceutical Federation
The International Pharmaceutical Federation or Fédération Internationale Pharmaceutique, abbreviated as FIP, is an international federation of national organizations that represent pharmacists and pharmaceutical scientists. It was founded in 1912 and is based in The Hague in the Netherlands. Mission statement The International Pharmaceutical Federation (FIP) is the global federation of national associations of pharmacists and pharmaceutical scientists. It gathers 127 member organizations and represents three million practitioners and scientists around the world. It is a nongovernmental organization (NGO) in official relations with the World Health Organization. The mission of FIP is to "improve global health by advancing pharmacy practice and science to enable better discovery, development, access to and safe use of appropriate, cost-effective, quality medicines worldwide."FIP. 2020 Vision - FIP's vision, mission and strategic plan. The Hague: FIP. 2008 History The Federation w ...
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American Pharmacists Association
The American Pharmacists Association (APhA, previously known as the American Pharmaceutical Association), founded in 1852, is the first-established professional society of pharmacists in the United States. The association consists of more than 62,000 practicing pharmacists, pharmaceutical scientists, student pharmacists, pharmacy technicians, and others interested in the profession. Nearly all U.S. pharmacy specialty organizations were originally a section or part of this association. Mary Munson Runge became the first woman and the first African-American elected president of this association in 1979; she was president for two terms, from 1979 to 1981. Organization All members choose one of these three Academies : *American Pharmacists Association - Academy of Pharmacy Practice and Management (APhA–APPM) *American Pharmacists Association - Academy of Pharmaceutical Research and Science (APhA–APRS) *American Pharmacists Association - Academy of Student Pharmacists ...
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American Association Of Colleges Of Pharmacy
The American Association of Colleges of Pharmacy (AACP) is the national organization representing the interests of pharmacy education. Founded in 1900, AACP comprises all accredited colleges and schools with pharmacy degree programs, including more than 6,400 faculty, 63,800 students enrolled in professional programs, and 4,800 individuals pursuing graduate study in the field of pharmacy. The mission of AACP is to lead and partner with our members in advancing pharmacy education, research, scholarship, practice and service to improve societal health. AACP provides member services – including meetings and events, webinars, continuing education, publications, reports and searchable directories for faculty, speakers and grants. AACP also works to promote the profession of pharmacy and the value of pharmacy education to audiences beyond the academic community. References External links AACP home pageOfficial Publication''The American Journal of Pharmaceutical Education The '' ...
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Rho Chi
Rho Chi () is an international honor society for pharmaceutical sciences. It was founded on May 19, 1922, to "encourage high scholastic achievement and fellowship among students in pharmacy and to promote the pharmaceutical sciences". History The organization evolved from the Aristolochite Society which had been established at the University of Michigan as a local honor society in 1908. Discussion of national expansion began in 1917, met with urging at that same time from pharmacy faculty, which resulted in a second chapter of Aristolochite being established in 1919 at what is now Oregon State University, and a third at the University of Oklahoma. The Society adopted the name Rho Chi Society that year, with the grant of a charter from the State of Michigan.Rho Chi Bylaws and History
from the ΡΧ National Website, accessed 11 June 2014
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American College Of Clinical Pharmacology
The American College of Clinical Pharmacology® (ACCP) is a national organization of clinical pharmacology healthcare professionals who seek to advance clinical pharmacology. History and mission In the 1960s, a group of physicians formulated the concept of an organization dedicated to a new branch of pharmacology that dealt with the effectiveness and safety of drugs in humans. As a result of their efforts, the American College of Clinical Pharmacology (ACCP) was founded on September 11, 1969. The mission is to improve health by optimizing therapeutics and to provide leadership and education that enables the generation, integration and translation of scientific knowledge to optimize research, development and utilization of medication. Structure ACCP is governed by a Board of Regents elected by ACCP Members. The Board is advised by a network of ACCP committees. Membership Levels of membership in ACCP are Retired, Student, Member and Fellow (FCP). Fellowship is the organization ...
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Sweden
Sweden, formally the Kingdom of Sweden,The United Nations Group of Experts on Geographical Names states that the country's formal name is the Kingdom of SwedenUNGEGN World Geographical Names, Sweden./ref> is a Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, Finland to the east, and is connected to Denmark in the southwest by a bridgetunnel across the Öresund. At , Sweden is the largest Nordic country, the third-largest country in the European Union, and the fifth-largest country in Europe. The capital and largest city is Stockholm. Sweden has a total population of 10.5 million, and a low population density of , with around 87% of Swedes residing in urban areas in the central and southern half of the country. Sweden has a nature dominated by forests and a large amount of lakes, including some of the largest in Europe. Many long rivers run from the Scandes range through the landscape, primarily ...
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Uppsala University
Uppsala University ( sv, Uppsala universitet) is a public university, public research university in Uppsala, Sweden. Founded in 1477, it is the List of universities in Sweden, oldest university in Sweden and the Nordic countries still in operation. The university rose to significance during the rise of Swedish Empire, Sweden as a great power at the end of the 16th century and was then given a relative financial stability with a large donation from King Gustavus Adolphus of Sweden, Gustavus Adolphus in the early 17th century. Uppsala also has an important historical place in Swedish national culture, identity and for the Swedish establishment: in historiography, literature, politics, and music. Many aspects of Swedish academic culture in general, such as the white student cap, originated in Uppsala. It shares some peculiarities, such as the student nation system, with Lund University and the University of Helsinki. Uppsala belongs to the Coimbra Group of European universities a ...
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Drug Interaction
Drug interactions occur when a drug's mechanism of action is disturbed by the concomitant administration of substances such as foods, beverages, or other drugs. The cause is often the inhibition of the specific receptors available to the drug, forcing the drug molecules to bind to other non-intended targets which results in an array of side-effects. The term selectivity describes a drug’s ability to target a single receptor, rendering a predictable physiological response. For example, the binding of acetylcholine to muscarinic tracheal smooth-muscle receptors (M3) results in smooth muscle contractions. When free receptors become occupied by agonists - drugs that bind and activate receptors - and antagonists - drugs that inhibit/ block activation - the opportunity for drugs to target their intended receptor decreases as most receptors are already occupied. Therefore, when the number of free receptors decreases, the drugs begin binding to other secondary receptors, causing s ...
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