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Leloir
Luis Federico Leloir (September 6, 1906 – December 2, 1987) was an Argentine physician and biochemist who received the 1970 Nobel Prize in Chemistry for his discovery of the metabolic pathways in lactose. Although born in France, Leloir received the majority of his education at the University of Buenos Aires and was director of the private research group Fundación Instituto Campomar until his death in 1987. His research into sugar nucleotides, carbohydrate metabolism, and renal hypertension garnered international attention and led to significant progress in understanding, diagnosing and treating the congenital disease galactosemia. Luis Leloir is buried in La Recoleta Cemetery, Buenos Aires. Biography Early years Leloir's parents, Federico Augusto Rufino Leloir Bernal and Hortensia Aguirre de Leloir, traveled from Buenos Aires to Paris in the middle of 1906 with the intention of treating Federico's illness. However, Federico died in late August, and a week later Luis was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
La Recoleta Cemetery
La Recoleta Cemetery ( es, Cementerio de la Recoleta) is a cemetery located in the Recoleta, Buenos Aires, Recoleta Barrios and Communes of Buenos Aires, neighbourhood of Buenos Aires, Argentina. It contains the graves of notable people, including Eva Perón, President of Argentina, presidents of Argentina, Nobel Prize winners, the founder of the Argentine Navy, and military commanders like Julio Argentino Roca. In 2011, the BBC hailed it as one of the world's best cemeteries, and in 2013, CNN listed it among the 10 most beautiful cemeteries in the world. History Franciscan Recollect monks () arrived in this area, then the outskirts of Buenos Aires, in the early eighteenth century. The cemetery is built around the Recollect Convent () and a church, Basilica of Our Lady of the Pillar, Buenos Aires, Our Lady of Pilar ('), built in 1732. The order was disbanded in 1822, and the garden of the convent was converted into the first public cemetery in Buenos Aires. Inaugurated on 17 Nov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Buenos Aires
The University of Buenos Aires ( es, Universidad de Buenos Aires, UBA) is a public university, public research university in Buenos Aires, Argentina. Established in 1821, it is the premier institution of higher learning in the country and one of the most prestigious universities of Ibero-America. It has educated 17 President of Argentina, Argentine presidents, produced four of the country's five Nobel Prize laureates, and is responsible for approximately 40% of the country's research output. The ''QS World University Rankings'' currently places the UBA at number 67, the highest ranking university in the Spanish-speaking world. The university's academic strength and regional leadership make it attractive to many international students, especially at the postgraduate level. Just over 4 percent of undergraduates are foreigners, while 15 percent of postgraduate students come from abroad. The Faculty of Economic Sciences, University of Buenos Aires, Faculty of Economic Sciences has t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Argentina
Argentina (), officially the Argentine Republic ( es, link=no, República Argentina), is a country in the southern half of South America. Argentina covers an area of , making it the second-largest country in South America after Brazil, the fourth-largest country in the Americas, and the eighth-largest country in the world. It shares the bulk of the Southern Cone with Chile to the west, and is also bordered by Bolivia and Paraguay to the north, Brazil to the northeast, Uruguay and the South Atlantic Ocean to the east, and the Drake Passage to the south. Argentina is a federal state subdivided into twenty-three provinces, and one autonomous city, which is the federal capital and largest city of the nation, Buenos Aires. The provinces and the capital have their own constitutions, but exist under a federal system. Argentina claims sovereignty over the Falkland Islands, South Georgia and the South Sandwich Islands, and a part of Antarctica. The earliest recorded human prese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louisa Gross Horwitz Prize
The Louisa Gross Horwitz Prize for Biology or Biochemistry is an annual prize awarded by Columbia University to a researcher or group of researchers who have made an outstanding contribution in basic research in the fields of biology or biochemistry. The prize was established at the bequest of S. Gross Horwitz and is named to honor his mother, Louisa Gross Horwitz, the daughter of trauma surgeon Samuel D. Gross. The prize was first awarded in 1967. As of October 2018, 51 (50%) of the 101 prize recipients have subsequently been awarded the Nobel Prize in Physiology or Medicine (40) or Chemistry (11). It is regarded as one of the important precursors of a future Nobel Prize award. Recipients *1967 Luis Leloir (1970 Chemistry) *1968 Har Gobind Khorana (1968 Physiology or Medicine), Marshall Warren Nirenberg (1968 Physiology or Medicine) *1969 Max Delbrück (1969 Physiology or Medicine), Salvador E. Luria (1969 Physiology or Medicine) *1970 Albert Claude (1974 Physiology or Medicine ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
San Clemente Del Tuyú
San Clemente del Tuyú is an Argentine town in the '' Partido de la Costa'' district of the Province of Buenos Aires. History Noticed by Ferdinand Magellan in 1520, who gave nearby Cape San Antonio its name, Spanish authorities first surveyed the area in 1580. Led by reformist Governor Hernando Arias de Saavedra, his Guaraní staff christened the spot ''Rincón del Tuyú'' ("muddy corner"). First mapped by British Jesuit Thomas Falkner in 1744, the neighboring stream was named ''San Clemente'' by Spanish Jesuit José Cardiel. The waterfront area was soon purchased by the Ortiz de Rozas family, one of Argentina's most well-established landowners. Sold to another prominent family, the Leloirs, in 1816, the area became a sheep ranch. A descendant of the Ortiz de Rozas', General Juan Manuel de Rosas, had the area incorporated into a district of the Province of Buenos Aires in 1825, the area's first assigned jurisdiction since national independence in 1816; as governor, Rosas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galactosemia
Galactosemia (British galactosaemia, from Greek γαλακτόζη + αίμα, meaning galactose + blood, accumulation of galactose in blood) is a rare genetic metabolic disorder that affects an individual's ability to metabolize the sugar galactose properly. Galactosemia follows an autosomal recessive mode of inheritance that confers a deficiency in an enzyme responsible for adequate galactose degradation. Friedrich Goppert (1870–1927), a German physician, first described the disease in 1917, with its cause as a defect in galactose metabolism being identified by a group led by Herman Kalckar in 1956. Galactosemia was the second disorder found to be detectable through newborn screening methods by Robert Guthrie. Its incidence is about 1 per 60,000 births for people of European ancestry. In other populations the incidence rate differs. Galactosaemia is about one hundred times more common (1:480 births) in the Irish Traveller population. Symptoms Adults Infants Infan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Galactosemia
Galactosemia (British galactosaemia, from Greek γαλακτόζη + αίμα, meaning galactose + blood, accumulation of galactose in blood) is a rare genetic metabolic disorder that affects an individual's ability to metabolize the sugar galactose properly. Galactosemia follows an autosomal recessive mode of inheritance that confers a deficiency in an enzyme responsible for adequate galactose degradation. Friedrich Goppert (1870–1927), a German physician, first described the disease in 1917, with its cause as a defect in galactose metabolism being identified by a group led by Herman Kalckar in 1956. Galactosemia was the second disorder found to be detectable through newborn screening methods by Robert Guthrie. Its incidence is about 1 per 60,000 births for people of European ancestry. In other populations the incidence rate differs. Galactosaemia is about one hundred times more common (1:480 births) in the Irish Traveller population. Symptoms Adults Infants Infan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arc De Triomphe
The Arc de Triomphe de l'Étoile (, , ; ) is one of the most famous monuments in Paris, France, standing at the western end of the Champs-Élysées at the centre of Place Charles de Gaulle, formerly named Place de l'Étoile—the ''étoile'' or "star" of the juncture formed by its twelve radiating avenues. The location of the arc and the plaza is shared between three arrondissements, 16th (south and west), 17th (north), and 8th (east). The Arc de Triomphe honours those who fought and died for France in the French Revolutionary and Napoleonic Wars, with the names of all French victories and generals inscribed on its inner and outer surfaces. Beneath its vault lies the Tomb of the Unknown Soldier from World War I. The central cohesive element of the ''Axe historique'' (historic axis, a sequence of monuments and grand thoroughfares on a route running from the courtyard of the Louvre to the Grande Arche de la Défense), the Arc de Triomphe was designed by Jean Chalgrin in 1806; i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms. Long-term high blood pressure, however, is a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide. High blood pressure is classified as primary (essential) hypertension or secondary hypertension. About 90–95% of cases are primary, defined as high blood pressure due to nonspecific lifestyle and genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, excess body weight, smoking, and alcohol use. The remaining 5–10% of cases are categorized as secondary high blood pressure, defined as high blood pressure due to an identifiable cause, such ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basque Country (historical Territory)
The Basque Country ( eu, Euskal Herria; es, País Vasco; french: Pays basque) is the name given to the home of the Basque people. Trask, R.L. ''The History of Basque'' Routledge: 1997 The Basque country is located in the western Pyrenees, straddling the border between France and Spain on the coast of the Bay of Biscay. ''Euskal Herria'' is the oldest documented Basque name for the area they inhabit, dating from the 16th century. It comprises the Autonomous Communities of the Basque Country and Navarre in Spain and the Northern Basque Country in France. The region is home to the Basque people ( eu, Euskaldunak), their language ( eu, Euskara), culture and traditions. The area is neither linguistically nor culturally homogeneous, and certain areas have a majority of people who do not consider themselves Basque, such as the south of Navarre. The concept is still highly controversial, and the Supreme Court of Navarre has ruled against scholarly books that include the Navarre comm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renal
The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood exits into the paired renal veins. Each kidney is attached to a ureter, a tube that carries excreted urine to the bladder. The kidney participates in the control of the volume of various body fluids, fluid osmolality, acid–base balance, various electrolyte concentrations, and removal of toxins. Filtration occurs in the glomerulus: one-fifth of the blood volume that enters the kidneys is filtered. Examples of substances reabsorbed are solute-free water, sodium, bicarbonate, glucose, and amino acids. Examples of substances secreted are hydrogen, ammonium, potassium and uric acid. The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains only ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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