|
Legonmycin
Legonmycins are a group of chemical compounds that belong to the pyrrolizidine family of naturally occurring alkaloids. Discovered by a joint team of researchers from University of Ghana, University of Aberdeen, and Wuhan University, the compounds were isolated from ''Streptomyces'' microorganisms in Legon, a suburb of Accra, Ghana Accra (; or ''Gaga''; ; Ewe: Gɛ; ) is the capital and largest city of Ghana, located on the southern coast at the Gulf of Guinea, which is part of the Atlantic Ocean. As of 2021 census, the Accra Metropolitan District, , had a population .... Laboratory syntheses of legonmycin A and legonmycin B have been reported. References Pyrrolizidine alkaloids {{Ghana-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Streptomyces
''Streptomyces'', from στρεπτός (''streptós''), meaning "twisted", and μύκης (''múkés''), meaning "fungus", is the largest genus of Actinomycetota, and the type genus of the family Streptomycetaceae. Over 700 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, and have very large genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin. Different strains of the same species may colonize very diverse environments. Streptomycetes are characterised by a complex secondary metabolism. Between 5-23% (average: 12%) of the protein-coding genes of each ''Streptomyces'' species are implicated in secondary metabolism. Streptomycetes produce over two-thirds of the clinically useful antibiotics of natural origin (e.g., neomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyrrolizidine Alkaloid
Pyrrolizidine alkaloids (PAs), sometimes referred to as necine bases, are a group of naturally occurring alkaloids based on the structure of pyrrolizidine. Their use dates back centuries and is intertwined with the discovery, understanding, and eventual recognition of their toxicity on humans and animals. History PAs were first discovered in plants in the 19th century, but their toxic effects were not immediately recognized. Instead, many PA-containing plants were traditionally used for medicinal purposes in various cultures around the world. For example, herbs containing PAs were used in traditional Chinese medicine and by Native American tribes for their purported therapeutic properties. It has been estimated that 3% of the world's flowering plants contain pyrrolizidine alkaloids. Honey can contain pyrrolizidine alkaloids, as can grains, milk, offal and eggs. To date (2011), there is no international regulation of PAs in food, unlike those for herbs and medicines. In the earl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Ghana
The University of Ghana is a public university located in Accra, Ghana. It is the oldest public university in the country. The university was founded in 1948 as the University College of the Gold Coast in the British colony of the Gold Coast. It was originally an affiliate college of the University of London, which supervised its academic programs and awarded degrees. After Ghana gained independence in 1957, the college was renamed the University College of Ghana. It changed it name again to the University of Ghana in 1961, when it gained full university status. The University of Ghana is situated on the west side of the Accra Legon Hills and northeast of the center of Accra. It has over 60,000 registered students. Introduction The original emphasis on establishing the University of Ghana was on the Liberal Arts, Social Sciences, Law, Basic Science, Agriculture, and Medicine. However, as part of a national educational reform program, the university's curriculum was expanded ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Aberdeen
The University of Aberdeen (abbreviated ''Aberd.'' in List of post-nominal letters (United Kingdom), post-nominals; ) is a public university, public research university in Aberdeen, Scotland. It was founded in 1495 when William Elphinstone, Bishop of Aberdeen and Chancellor of Scotland, petitioned Pope Alexander VI on behalf of James IV, King of Scots to establish King's College, Aberdeen, King's College, making it one of Scotland's four Ancient universities of Scotland, ancient universities and the List of oldest universities in continuous operation, fifth-oldest university in the English-speaking world. Along with the universities of University of St Andrews, St Andrews, University of Glasgow, Glasgow, and University of Edinburgh, Edinburgh, the university was part of the Scottish Enlightenment during the 18th century. The university as it is currently constituted was formed in 1860 by a merger between King's College, Aberdeen, King's College and Marischal College, a second un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wuhan University
Wuhan University (WHU; 武汉大学) is a key comprehensive public university in Wuhan, Hubei, China. It is directly affiliated with and funded by the Ministry of Education of the People's Republic of China, Ministry of Education of China. The university is part of Project 985, Project 211, and a pioneer in the Double First-Class Construction initiative. History The university's origins trace back to 1893 with the establishment of Ziqiang Institute by Zhang Zhidong, the then governor of Hubei and Hunan provinces during the late Qing Dynasty (1644-1911). In 1926, National Wuchang University, National Wuchang University of Commerce, Hubei Provincial Medical University, Hubei Provincial University of Legislation, Hubei Provincial University of Liberal Arts, and the private Wuchang Zhonghua University were merged into National Wuchang Sun Yat-sen University (also known as National Second Sun Yat-sen University). The school has an undergraduate department and 6 subjects including libe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legon
Legon , a suburb of the Ghanaian city Accra, is situated about north-east of the city center in the Ayawaso West Municipal District, a district in the Greater Accra Region of Ghana. Legon is home to the main campus of the University of Ghana. Ghanaians loosely refer to the University of Ghana simply as "Legon". Legon is also home to a few of Ghana's well known educational institutions such as Presbyterian Boys' Secondary School (PRESEC-Legon), Ghana Institute of Management and Public Administration(GIMPA) and the University of Professional Studies, Accra(UPSA). Legon is adjacent to one of the most prestigious residential suburbs of Accra - East Legon and only about 20 minutes drive from the Kotoka International Airport. Education The university has its own Elementary school, elementary and middle schools known commonly as the University of Ghana Primary School Legon, University Primary and Junior Secondary School (UPS) and the University of Ghana Staff Village Basic School. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Accra
Accra (; or ''Gaga''; ; Ewe: Gɛ; ) is the capital and largest city of Ghana, located on the southern coast at the Gulf of Guinea, which is part of the Atlantic Ocean. As of 2021 census, the Accra Metropolitan District, , had a population of 284,124 inhabitants, and the larger Greater Accra Region, , had a population of 5,455,692 inhabitants. In common usage, the name "Accra" often refers to the territory of the Accra Metropolitan District as it existed before 2008, when it covered .Sum of the land areas of Accra Metropolitan District, Ablekuma Central Municipal District, Ablekuma North Municipal District, Ablekuma West Municipal District, Ayawaso Central Municipal District, Ayawaso East Municipal District, Ayawaso North Municipal District, Ayawaso West Municipal District, Korle Klottey Municipal District, Krowor Municipal District, La Dade Kotopon Municipal District, La Dadekotopon Municipal District, Ledzokuku Municipal District, and Okaikwei North Municipal District, Okaiko ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
