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Leadiant Biosciences
Leadiant Biosciences, formerly known as Sigma-Tau Industrie Farmaceutiche Riunite, was founded in 1957 by research chemist Claudio Cavazza. In 2018 Leadiant Biosciences has come under fire for creating a monopoly for CDCA and unnecessarily increasing the price by a factor of 335. Construction began in 1964 of an industrial facility in Pomezia equipped with state-of-the-art automatic production machinery to provide steady employment for 64 people. The choice of Pomezia for its headquarters created one of the first industrialization and urban development initiatives in an area of Central-southern Italy that had previously been mainly devoted to agriculture. With the creation and launch of the Rekord B12 vitamin complex in September 1966 – an antiasthenic medicine that soon spread within the field of restorative infantile therapies – Sigma-Tau definitively asserted itself as a pharmaceutical manufacturer in Italy and abroad. From the 1970s to today From the 1970s onwards, ...
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Pomezia
Pomezia () is a municipality (''comune'') in the Metropolitan City of Rome Capital, Lazio, central Italy. In 2009 it had a population of about 60,000. History The town was built entirely new near the location of ancient Lavinium on land resulting from the final reclamation of the Pontine Marshes under Benito Mussolini, being inaugurated on 29 October 1939. Its new population was extracted from the poor peasants of Romagna, Veneto and Friuli. Peace did not last long. After being occupied by the forces of the Third Reich, Pomezia was heavily bombed during the Battle of Anzio in World War II. After the end of the war, Pomezia developed as a strong industrial center, especially in the medical and pharmaceutical sectors, as well as a recreational center. It is also home to the production plant of Italian food company Colavita. ''Pratica di Mare'' is the ''frazione'' of Pomezia where the ruins of the ancient port of Lavinium are located, now from the Tyrrhenian Sea. The ancient communi ...
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European Medicines Agency
The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of medicinal products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency (EMEA).Set up by EC Regulation No. 2309/93 as the European Agency for the Evaluation of Medicinal Products, and renamed by EC Regulation No. 726/2004 to the European Medicines Agency, it had the acronym EMEA until December 2009. The European Medicines Agency does not call itself EMA either – it has no official acronym but may reconsider if EMA becomes commonly accepted (secommunication on new visual identity an). The EMA was set up in 1995, with funding from the European Union and the pharmaceutical industry, as well as indirect subsidy from member states, its stated intention to harmonise (but not replace) the work of existing national medicine regulatory bodies. The hope was that this plan would not onl ...
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India
India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast, it shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the north; and Bangladesh and Myanmar to the east. In the Indian Ocean, India is in the vicinity of Sri Lanka and the Maldives; its Andaman and Nicobar Islands share a maritime border with Thailand, Myanmar, and Indonesia. Modern humans arrived on the Indian subcontinent from Africa no later than 55,000 years ago., "Y-Chromosome and Mt-DNA data support the colonization of South Asia by modern humans originating in Africa. ... Coalescence dates for most non-European populations average to between 73–55 ka.", "Modern human beings—''Homo sapiens''—originated in Africa. Then, int ...
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Unicef
UNICEF (), originally called the United Nations International Children's Emergency Fund in full, now officially United Nations Children's Fund, is an agency of the United Nations responsible for providing Humanitarianism, humanitarian and Development aid, developmental aid to children worldwide. The agency is among the most widespread and recognizable social welfare organizations in the world, with a presence in 192 countries and territories. UNICEF's activities include providing immunizations and disease prevention, administering Antiretroviral drug, treatment for children and mothers with HIV, enhancing childhood and maternal nutrition, improving sanitation, promoting education, and providing emergency relief in response to disasters. UNICEF is the successor of the United Nations International Children's Emergency Fund, created on 11 December 1946, in New York, by the United Nations Relief and Rehabilitation Administration, U.N. Relief Rehabilitation Administration to provide ...
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Partnerships
A partnership is an arrangement where parties, known as business partners, agree to cooperate to advance their mutual interests. The partners in a partnership may be individuals, businesses, interest-based organizations, schools, governments or combinations. Organizations may partner to increase the likelihood of each achieving their mission and to amplify their reach. A partnership may result in issuing and holding equity or may be only governed by a contract. History Partnerships have a long history; they were already in use in medieval times in Europe and in the Middle East. According to a 2006 article, the first partnership was implemented in 1383 by Francesco di Marco Datini, a merchant of Prato and Florence. The Covoni company (1336-40) and the Del Buono-Bencivenni company (1336-40) have also been referred to as early partnerships, but they were not formal partnerships. In Europe, the partnerships contributed to the Commercial Revolution which started in the 13th centur ...
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Netherlands Authority For Consumers And Markets
The Netherlands Authority for Consumers and Markets (Dutch: ''Autoriteit Consument & Markt (ACM)'') is the competition regulator in The Netherlands. It is a regulatory authority based in The Hague. It is charged with competition oversight, sector-specific regulation of several sectors, and enforcement of consumer protection laws. It enforces Section 24 of the Dutch Competition Act. Organisation The Authority falls under the responsibility of the Ministry of Economic Affairs and Climate Policy and employs around 600 persons, divided over multiple Directions e.g. Direction of Consumers, Competition, Healthcare, Transportation etc. History ACM was founded on 1 April 2013 through the merger of the Consumer Authority (Consumentenautoriteit, CA), the Independent Postal and Telecommunications Authority (Onafhankelijke Post en Telecommunicatie Autoriteit, OPTA), and the Netherlands Competition Authority (Nederlandse Mededingingsautoriteit, NMa). Notable cases In 2017 ACM imposed a fin ...
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Pharmaceutical Accountability Foundation
The Pharmaceutical Accountability Foundation (in Dutch Stichting Farma Ter Verantwoording) was established in Amsterdam in July 2018 to deal with pharmaceutical companies that demand excessive prices for medicines in the Netherlands. This followed a report by the in 2017. Wilbert Bannenberg, an epidemiologist, is the chairman. The group plans to deploy both health and pharmaceutical expertise and lawyers. They have investigated 12 cases all with the same business model, which they describe as: "buy an old, cheap product, get the old versions off the market, win orphan drug designation, and put up the price as high as you can." They say that European orphan drug legislation needs to be reformed. It plans to make a referral to the Netherlands Authority for Consumers and Markets in respect of the pricing policy of Leadiant Biosciences Ltd, formerly known as Sigma-Tau Rare Disease, for chenodeoxycholic acid which is used to treat about 60 children with cerebrotendineous xanthomatosis ...
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Industrial Wastewater Treatment
Industrial wastewater treatment describes the processes used for treating wastewater that is produced by industries as an undesirable by-product. After treatment, the treated industrial wastewater (or effluent) may be reused or released to a sanitary sewer or to a surface water in the environment. Some industrial facilities generate wastewater that can be treated in sewage treatment plants. Most industrial processes, such as petroleum refineries, chemical and petrochemical plants have their own specialized facilities to treat their wastewaters so that the pollutant concentrations in the treated wastewater comply with the regulations regarding disposal of wastewaters into sewers or into rivers, lakes or oceans. This applies to industries that generate wastewater with high concentrations of organic matter (e.g. oil and grease), toxic pollutants (e.g. heavy metals, volatile organic compounds) or nutrients such as ammonia. Some industries install a pre-treatment system to remove som ...
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Respiratory System
The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies greatly, depending on the size of the organism, the environment in which it lives and its evolutionary history. In land animals the respiratory surface is internalized as linings of the lungs. Gas exchange in the lungs occurs in millions of small air sacs; in mammals and reptiles these are called alveoli, and in birds they are known as atria. These microscopic air sacs have a very rich blood supply, thus bringing the air into close contact with the blood. These air sacs communicate with the external environment via a system of airways, or hollow tubes, of which the largest is the trachea, which branches in the middle of the chest into the two main bronchi. These enter the lungs where they branch into progressively narrower secondary and tert ...
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts. It is a structure composed of nervous tissue positioned along the rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain (precursor structures exist in onychophorans, gastropods and lancelets). The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal cord are both enclosed in the meninges. The meninges provide a barrier to chemicals dissolv ...
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