Late Devonian Genus Extinctions
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Late Devonian Genus Extinctions
Late may refer to: * LATE, an acronym which could stand for: ** Limbic-predominant age-related TDP-43 encephalopathy, a proposed form of dementia ** Local-authority trading enterprise, a New Zealand business law ** Local average treatment effect, a concept in econometrics Music * ''Late'' (album), a 2000 album by The 77s * Late!, a pseudonym used by Dave Grohl on his ''Pocketwatch'' album * Late (rapper), an underground rapper from Wolverhampton * "Late" (song), a song by Blue Angel * "Late", a song by Kanye West from ''Late Registration'' Other * Late (Tonga), an uninhabited volcanic island southwest of Vavau in the kingdom of Tonga * "Late" (''The Handmaid's Tale''), a television episode * LaTe, Oy Laivateollisuus Ab, a defunct shipbuilding company * Late may refer to a person who is Dead See also * * * ''Lates'', a genus of fish in the lates perch family * Later (other) * Tardiness * Tardiness (scheduling) In scheduling, tardiness is a measure of a delay in exe ...
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Limbic-predominant Age-related TDP-43 Encephalopathy
LATE is a term that describes a prevalent condition with impaired memory and thinking in advanced age, often culminating in the dementia clinical syndrome. In other words, the symptoms of LATE are similar to those of Alzheimer's disease.   The acronym LATE stands for Limbic-predominant Age-related TDP-43 Encephalopathy: “Limbic system, limbic” is related to the brain areas first involved, “age-related” and the name “LATE” itself refer to the onset of disease usually in persons aged 80 or older,  “TDP-43” indicates the aberrant mis-folded protein (or proteinopathy) deposits in the brain that characterize LATE, and “encephalopathy” means illness of brain. At present LATE can only be diagnosed with certainty at autopsy. The terminology used to refer to the brain changes identified in autopsy-confirmed LATE is: LATE neuropathologic change (LATE-NC). The diagnosis of LATE-NC at autopsy requires detection of pathologic TDP-43 protein deposits in the brain, especi ...
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