Krikor Pambuccian
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Krikor Pambuccian
Krikor (Grigore) Pambuccian ( hy, Գրիգոր Բամպուքծեան; 23 August 1915 – 1996) was an Armenian–Romanian Professor of Pathology at the Carol Davila University of Medicine and Pharmacy and longtime Vice-President of the Armenian Apostolic Parish of Romania (1944-1993). Life and career Krikor (Grigore) Pambuccian was born in Adana, a city in the eastern Ottoman Empire (present Turkey). During the Armenian genocide his family was forced to leave and ended up as stateless refugees, holders of the Nansen passport, going through Damascus, Cairo, Alexandria, Larnaca, to settle in Constanța. There he studied at the Deutsche Evangelische Volksschule and at the Mircea cel Bătrân High School, which he graduated as Valedictorian. He studied medicine at the Carol Davila University of Medicine and Pharmacy between 1936 and 1942, was a battalion physician during World War II, and then climbed the ladders of an academic career to become, in 1973, Professor of Pathology at ...
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Armenian Romanian
Armenians have been present in what is now Romania and Moldova for over a millennium, and have been an important presence as traders since the 14th century. Numbering only in the thousands in modern times, they were culturally suppressed in the Communist era, but have undergone a cultural revival since the Romanian Revolution of 1989. History Danubian Principalities The earliest traces of Armenians in what was later Moldavia are dated by 967 (recorded presence in Cetatea Albă). Early Armenian Diasporas stemmed in the fall of the Bagratuni rule and other disasters, including the Mongol invasion. In 1572–1574, Ioan Vodă cel Cumplit was Hospodar (Prince) of Moldavia, grandson of Stephen the Great, son of Bogdan III and his Armenian concubine Serpega. Armenian expatriates were awarded tax exemptions at different times in the Danubian Principalities' history. Encouraged to settle as early as the 14th century, they became a familiar presence in towns, usually as the main e ...
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Cerebrotendineous Xanthomatosis
Cerebrotendinous xanthomatosis, also called cerebral cholesterosis, is an autosomal recessive form of xanthomatosis. It falls within a group of genetic disorders called the leukodystrophies. Presentation An inherited disorder associated with the deposition of a steroid known as cholestanol in the brain and other tissues and with elevated levels of cholesterol in plasma but with normal total cholesterol level; it is characterized by progressive cerebellar ataxia beginning after puberty and by juvenile cataracts, juvenile or infantile onset chronic diarrhea, childhood neurological deficit, and tendineous or tuberous xanthomas. Genetics CTX is associated with mutations in the CYP27A1 gene, located on chromosome 2q33-qter. The disorder is inherited in an autosomal recessive manner. This means the defective gene responsible for the disorder is located on an autosome (chromosome 2 is an autosome), and two copies of the defective gene (one inherited from each parent) are required in o ...
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Armenian Apostolic Church
, native_name_lang = hy , icon = Armenian Apostolic Church logo.svg , icon_width = 100px , icon_alt = , image = Էջմիածնի_Մայր_Տաճար.jpg , imagewidth = 250px , alt = , caption = Etchmiadzin Cathedral, the mother church of the Armenian Apostolic Church , abbreviation = , type = , main_classification = Eastern Christian , orientation = Oriental Orthodox , scripture = Septuagint, New Testament, Armenian versions , theology = Miaphysitism , polity = Episcopal , governance = Mother See of Holy Etchmiadzin , structure = , leader_title = Head , leader_name = Catholicos of All Armenians Karekin II , leader_title1 = , leader_name1 = , leader_title2 = , leader_name2 = , leader_title3 = , leader_name3 = , associations ...
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Catholicos
Catholicos, plural Catholicoi, is a title used for the head of certain churches in some Eastern Christian traditions. The title implies autocephaly and in some cases it is the title of the head of an autonomous church. The word comes from ancient Greek , pl. , derived from (, "generally") from (, "down") and (, "whole"), meaning "concerning the whole, universal, general"; it originally designated a financial or civil office in the Roman Empire.Wigram, p. 91. The name of the Catholic Church comes from the same word—however, the title "Catholicos" does not exist in its hierarchy. The Church of the East, some Oriental Orthodox, Eastern Orthodox, and Eastern Catholic churches historically use this title;The Motu Proprio ''Cleri Sanctitati'' Canon 335 for example the Armenian Apostolic Church and the Georgian Orthodox Church. In the Church of the East, the title was given to the church's head, the Patriarch of the Church of the East. It is still used in two successor churches, th ...
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Vazgen I
Vazgen I also Vazken I of Bucharest, (), born Levon Garabed Baljian ( hy, Լևոն Կարապետ Աբրահամի Պալճյան; September 20, 1908 – August 18, 1994) was the Catholicos of All Armenians between 1955 and 1994, for a total of 39 years, the 4th longest reign in the history of the Armenian Apostolic Church. The following three served for 39 years as Catholicos of All Armenians or Catholicos of the Great House of Cilicia: #Peter I (1019–1058) — Պետրոս Ա Գետադարձ (Catholicos of All Armenians), #Gregory II the Martyrophile (1066–1105) — Գրիգոր Բ. Վկայասէր ( Catholicos of the Great House of Cilicia) and #David IV (1590–1629), d. 1633 — Դավիթ Դ Վաղարշապատցի (Catholicos of All Armenians). The three longest reigning Catholicoi were: #) Nerses IV the Graceful (1166–1173) -- Սուրբ Ներսէս Դ. Կլայեցի (Շնորհալի), who served 53 years as Catholicos of the Great House of Cilicia, #) Constan ...
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Dental Implants
A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodontic anchor. The basis for modern dental implants is a biologic process called osseointegration, in which materials such as titanium or zirconia form an intimate bond to bone. The implant fixture is first placed so that it is likely to osseointegrate, then a dental prosthetic is added. A variable amount of healing time is required for osseointegration before either the dental prosthetic (a tooth, bridge or denture) is attached to the implant or an abutment is placed which will hold a dental prosthetic/crown. Success or failure of implants depends on the health of the person receiving the treatment, drugs which affect the chances of osseointegration, and the health of the tissues in the mouth. The amount of stress that will be put on the impla ...
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Adrenocortical Hormones
In humans and other animals, the adrenocortical hormones are hormones produced by the adrenal cortex, the outer region of the adrenal gland. These polycyclic steroid hormones have a variety of roles that are crucial for the body’s response to stress (for example, the fight-or-flight response), and they also regulate other functions in the body. Threats to homeostasis, such as injury, chemical imbalances, infection, or psychological stress, can initiate a stress response. Examples of adrenocortical hormones that are involved in the stress response are aldosterone and cortisol. These hormones also function in regulating the conservation of water by the kidneys and glucose metabolism, respectively.Genest, J., Biron, P., Koiw, E., Nowaczynski, W., Chretien, M., & Boucher, R. (1961). Adrenocortical hormones in human hypertension and their relation to angiotensin. Circulation Research, 9, 775-791. Classes Adrenocortical hormones are divided into three classes by function: mineraloc ...
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Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which the heart becomes thickened without an obvious cause. The parts of the heart most commonly affected are the interventricular septum and the ventricles. This results in the heart being less able to pump blood effectively and also may cause electrical conduction problems. People who have HCM may have a range of symptoms. People may be asymptomatic, or may have fatigue, leg swelling, and shortness of breath. It may also result in chest pain or fainting. Symptoms may be worse when the person is dehydrated. Complications may include heart failure, an irregular heartbeat, and sudden cardiac death. HCM is most commonly inherited from a person's parents in an autosomal dominant pattern. It is often due to mutations in certain genes involved with making heart muscle proteins. Other inherited causes of left ventricular hypertrophy may include Fabry disease, Friedreich's ataxia, and certain medica ...
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Sudden Infant Death Syndrome
Sudden infant death syndrome (SIDS) is the sudden unexplained death of a child of less than one year of age. Diagnosis requires that the death remain unexplained even after a thorough autopsy and detailed death scene investigation. SIDS usually occurs during sleep. Typically death occurs between the hours of midnight and 9:00 a.m. There is usually no noise or evidence of struggle. SIDS remains the leading cause of infant mortality in Western countries, contributing to half of all post-neonatal deaths. The exact cause of SIDS is unknown. The requirement of a combination of factors including a specific underlying susceptibility, a specific time in development, and an environmental stressor has been proposed. These environmental stressors may include sleeping on the stomach or side, overheating, and exposure to tobacco smoke. Accidental suffocation from bed sharing (also known as co-sleeping) or soft objects may also play a role. Another risk factor is being born before 39 ...
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Syphilis
Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter) though there may be multiple sores. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. There may also be sores in the mouth or vagina. In latent syphilis, which can last for years, there are few or no symptoms. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. Syphilis has been known as "the great imitator" as it may cause symptoms similar to many other diseases. Syphilis is most commonly spread through sexual activity. It may also be transmi ...
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Prednisone
Prednisone is a glucocorticoid medication mostly used to immunosuppressive drug, suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other steroids. It is taken Oral administration, by mouth. Common side effects with long-term use include cataracts, Osteoporosis, bone loss, easy bruising, muscle weakness, and oral candidiasis, thrush. Other side effects include weight gain, swelling, high blood sugar, increased risk of infection, and psychosis. It is generally considered safe in pregnancy and low doses appear to be safe when breastfeeding. After prolonged use, prednisone needs to be stopped gradually. Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. Pred ...
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Aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat include Kawasaki disease, pericarditis, and rheumatic fever. Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. For pain or fever, effects typically begin within 30 minutes. Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. One common adverse effect is an upset stomach. More significant side effects include stomach ulcers, stomach bleeding, and worsening asthma. Bleeding risk is greater among those who are older, drink alcohol, take other NSAIDs, or are on other blood thinners. Aspirin is not recommended in the last part of pregnancy. It is not generally recommended in children with infections because of the risk of ...
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