Krikor (Grigore) Pambuccian ( hy, Գրիգոր Բամպուքծեան; 23 August 1915 – 1996) was an
Armenian–Romanian Professor of Pathology at the
Carol Davila University of Medicine and Pharmacy
Carol Davila University of Medicine and Pharmacy ( ro, Universitatea de Medicină și Farmacie „Carol Davila”) or University of Medicine and Pharmacy Bucharest, commonly known by the abbreviation UMFCD, is a public health sciences university i ...
and longtime Vice-President of the Armenian Apostolic Parish of Romania (1944-1993).
Life and career
Krikor (Grigore) Pambuccian was born in
Adana
Adana (; ; ) is a major city in southern Turkey. It is situated on the Seyhan River, inland from the Mediterranean Sea. The administrative seat of Adana Province, Adana province, it has a population of 2.26 million.
Adana lies in the heart ...
, a city in the eastern
Ottoman Empire
The Ottoman Empire, * ; is an archaic version. The definite article forms and were synonymous * and el, Оθωμανική Αυτοκρατορία, Othōmanikē Avtokratoria, label=none * info page on book at Martin Luther University) ...
(present
Turkey
Turkey ( tr, Türkiye ), officially the Republic of Türkiye ( tr, Türkiye Cumhuriyeti, links=no ), is a list of transcontinental countries, transcontinental country located mainly on the Anatolia, Anatolian Peninsula in Western Asia, with ...
). During the
Armenian genocide
The Armenian genocide was the systematic destruction of the Armenians in the Ottoman Empire, Armenian people and identity in the Ottoman Empire during World War I. Spearheaded by the ruling Committee of Union and Progress (CUP), it was ...
his family was forced to leave and ended up as stateless refugees, holders of the
Nansen passport
Nansen passports, originally and officially stateless persons passports, were internationally recognized refugee travel documents from 1922 to 1938, first issued by the League of Nations's Office of the High Commissioner for Refugees to stateles ...
, going through
Damascus
)), is an adjective which means "spacious".
, motto =
, image_flag = Flag of Damascus.svg
, image_seal = Emblem of Damascus.svg
, seal_type = Seal
, map_caption =
, ...
,
Cairo
Cairo ( ; ar, القاهرة, al-Qāhirah, ) is the capital of Egypt and its largest city, home to 10 million people. It is also part of the largest urban agglomeration in Africa, the Arab world and the Middle East: The Greater Cairo metro ...
,
Alexandria
Alexandria ( or ; ar, ٱلْإِسْكَنْدَرِيَّةُ ; grc-gre, Αλεξάνδρεια, Alexándria) is the second largest city in Egypt, and the largest city on the Mediterranean coast. Founded in by Alexander the Great, Alexandria ...
,
Larnaca
Larnaca ( el, Λάρνακα ; tr, Larnaka) is a city on the south east coast of Cyprus and the capital of the district of the same name. It is the third-largest city in the country, after Nicosia and Limassol, with a metro population of 144 ...
, to settle in
Constanța
Constanța (, ; ; rup, Custantsa; bg, Кюстенджа, Kyustendzha, or bg, Констанца, Konstantsa, label=none; el, Κωνστάντζα, Kōnstántza, or el, Κωνστάντια, Kōnstántia, label=none; tr, Köstence), histo ...
. There he studied at the Deutsche Evangelische Volksschule and at the
Mircea cel Bătrân High School, which he graduated as
Valedictorian
Valedictorian is an academic title for the highest-performing student of a graduating class of an academic institution.
The valedictorian is commonly determined by a numerical formula, generally an academic institution's grade point average (GPA ...
. He studied medicine at the
Carol Davila University of Medicine and Pharmacy
Carol Davila University of Medicine and Pharmacy ( ro, Universitatea de Medicină și Farmacie „Carol Davila”) or University of Medicine and Pharmacy Bucharest, commonly known by the abbreviation UMFCD, is a public health sciences university i ...
between 1936 and 1942, was a battalion physician during World War II,
and then climbed the ladders of an academic career to become, in 1973, Professor of Pathology at the
Carol Davila University of Medicine and Pharmacy
Carol Davila University of Medicine and Pharmacy ( ro, Universitatea de Medicină și Farmacie „Carol Davila”) or University of Medicine and Pharmacy Bucharest, commonly known by the abbreviation UMFCD, is a public health sciences university i ...
.
Pambuccian's son Stefan (1957-2020) also became a pathologist.
As Vice-President of the Armenian Apostolic Parish of Romania, he aimed at preserving, to the best of his ability, the religious patrimony of the Armenian community in Romania during a difficult time for both the Armenian community and Romania.
Works
In his thesis (''Experimental chemical cancer'') of 1942 he studied tar-induced cancer in rats. Later on, the range of research topics widened to include the pathology of the heart and the blood vessels, the tumors of the heart, the pathology of the digestive tract, of the liver and the pancreas, the pathology of the infant, pre-cancerous states and in situ cancer, the pathology of the mouth (in particular
Lichen planus
Lichen planus (LP) is a chronic inflammatory and immune-mediated disease that affects the skin, nails, hair, and mucous membranes. It is not an actual lichen, and is only named that because it looks like one. It is characterized by polygonal, fla ...
), accidental and professional exposure to toxins (in the late 1960s and early 1970s doing an in-depth study of the toxic (carcinogenic) nature of the environment of
Copşa Mică),
toxic reactions to
phenylhydrazine
Phenylhydrazine is the chemical compound with the formula . It is often abbreviated as . It is also found in edible mushrooms.
Properties
Phenylhydrazine forms monoclinic prisms that melt to an oil around room temperature which may turn yellow ...
, hypertoxic forms of viral disease, suppurating pulmonary infections,
cerebrotendineous xanthomatosis
Cerebrotendinous xanthomatosis, also called cerebral cholesterosis, is an autosomal recessive form of xanthomatosis. It falls within a group of genetic disorders called the leukodystrophies.
Presentation
An inherited disorder associated with the ...
, visceral lesions in
rheumatic disorder
Rheumatism or rheumatic disorders are conditions causing chronic, often intermittent pain affecting the joints or connective tissue. Rheumatism does not designate any specific disorder, but covers at least 200 different conditions, including a ...
and
rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involv ...
,
trichinosis
Trichinosis, also known as trichinellosis, is a parasitic disease caused by roundworms of the ''Trichinella'' type. During the initial infection, invasion of the intestines can result in diarrhea, abdominal pain, and vomiting. Migration of larv ...
, the reactions of the gastric mucosa to
aspirin
Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and/or inflammation, and as an antithrombotic. Specific inflammatory conditions which aspirin is used to treat inc ...
, and to aspirin combined with
prednisone
Prednisone is a glucocorticoid medication mostly used to immunosuppressive drug, suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. It is also used to treat high blood calcium ...
, experimental research in
syphilis
Syphilis () is a sexually transmitted infection caused by the bacterium ''Treponema pallidum'' subspecies ''pallidum''. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, an ...
and in
trichinosis
Trichinosis, also known as trichinellosis, is a parasitic disease caused by roundworms of the ''Trichinella'' type. During the initial infection, invasion of the intestines can result in diarrhea, abdominal pain, and vomiting. Migration of larv ...
,
sudden infant death syndrome
Sudden infant death syndrome (SIDS) is the sudden unexplained death of a child of less than one year of age. Diagnosis requires that the death remain unexplained even after a thorough autopsy and detailed death scene investigation. SIDS usuall ...
, and on
hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which the heart becomes thickened without an obvious cause. The parts of the heart most commonly affected are the interventricular septum and the ventricles. This r ...
caused by hypersecretion of
adrenocortical hormones.
He pioneered the pathological study of the effects of
dental implants
A dental implant (also known as an endosseous implant or fixture) is a prosthesis that interfaces with the bone of the jaw or skull to support a dental prosthesis such as a crown, bridge, denture, or facial prosthesis or to act as an orthodonti ...
on the oral cavity, in collaboration with
Dr. Grigore Osipov-Sinești (1907-1989) and with Ernst Helmut Pruin (1913-2008) and Benedict Heinrich.
Recognition
In 1978, he was awarded the Saint Nerses Shnorhali medal by
Vazgen I
Vazgen I also Vazken I of Bucharest, (), born Levon Garabed Baljian ( hy, Լևոն Կարապետ Աբրահամի Պալճյան; September 20, 1908 – August 18, 1994) was the Catholicos of All Armenians between 1955 and 1994, for a total of 39 ...
, the
Catholicos
Catholicos, plural Catholicoi, is a title used for the head of certain churches in some Eastern Christian traditions. The title implies autocephaly and in some cases it is the title of the head of an autonomous church. The word comes from ancient ...
of the
Armenian Apostolic Church
, native_name_lang = hy
, icon = Armenian Apostolic Church logo.svg
, icon_width = 100px
, icon_alt =
, image = Էջմիածնի_Մայր_Տաճար.jpg
, imagewidth = 250px
, a ...
.
[Victor Pambuccian, ''File din viața lui Krikor Pambuccian''. Editura Ararat, București, 2015, p. 69]
Publications
* (co-author) ''Morfopatologia aparatului cardiovascular'' (1959)
* (co-author) ''Diagnosticul precoce al tumorilor maligne'' (1964)
* (co-author)''Trichineloza'' (1970)
* (co-author) ''Anatomia patologică'' (1980)
* ''Morfopatologie stomatologică'' (1987)
References
Victor Pambuccian, ''File din viața lui Krikor Pambuccian''. Editura Ararat, București, 2015
Notes
{{DEFAULTSORT:Pambuccian, Krikor
1915 births
1996 deaths
People from Adana
Pathologists
Romanian people of Armenian descent
Armenians from the Ottoman Empire
Emigrants from the Ottoman Empire to Romania
Refugees in Romania
Mircea cel Bătrân National College (Constanța) alumni