|
Klaus Rajewsky
Klaus Rajewsky (born 12 November 1936 in Frankfurt am Main) is a German immunologist, renowned for his work on B cells. He studied medicine in Frankfurt, Munich and at the Pasteur Institute, Paris. In 1964 he started working at the Institute of Genetics in the University of Cologne, where he became professor for genetics. He researched Hodgkin's disease and the role of B cells within the immune system. He also developed conditional knockout mice based on Cre-Lox recombination. He is one of the founding fathers of the German society for immunology (1967). Since 1994 he has been a member of the United States National Academy of Sciences. From 1995 to 2001 he was head of the Monterotondo station of the European Molecular Biology Laboratory near Rome. In 1996 he was awarded the Robert Koch Prize (shared with Fritz Melchers). In 1998 he founded Artemis Pharmaceuticals, together with Christiane Nüsslein-Volhard and Peter Stadler. In 2001 he started working at the Center fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frankfurt Am Main
Frankfurt, officially Frankfurt am Main (; Hessian: , "Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its namesake Main River, it forms a continuous conurbation with the neighboring city of Offenbach am Main and its urban area has a population of over 2.3 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.6 million and is Germany's second-largest metropolitan region after the Rhine-Ruhr region. Frankfurt's central business district, the Bankenviertel, lies about northwest of the geographic center of the EU at Gadheim, Lower Franconia. Like France and Franconia, the city is named after the Franks. Frankfurt is the largest city in the Rhine Franconian dialect area. Frankfurt was a city state, the Free City of Frankfurt, for nearly five centuries, and was one of the most import ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rome
, established_title = Founded , established_date = 753 BC , founder = King Romulus (legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = Country , subdivision_name = Italy , subdivision_type2 = Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan city , subdivision_name3 = Rome Capital , government_footnotes= , government_type = Strong Mayor–Council , leader_title2 = Legislature , leader_name2 = Capitoline Assemb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nikolaus Rajewsky
Nikolaus Rajewsky (born 1968) is a German system biologist at the Max-Delbrück-Center for Molecular Medicine (MDC) and at the Charité in Berlin. He founded and directs the “Berlin Institute for Medical Systems Biology” (BIMSB, Max-Delbrück-Center for Molecular Medicine). He leads the Rajewsky lab, where he studies how RNA regulates gene expression. He also co-chairs LifeTime, a pan-European research initiative of more than 90 academic institutions and 70 companies, which aims to revolutionize healthcare by mapping, understanding, and targeting cells during disease progression. LifeTime integrates several technologies: single-cell multiomics, machine learning, and personalized disease models such as organoids. Rajewsky has received numerous awards and honors, including the most prestigious German award, the Gottfried Wilhelm Leibniz Prize, endowed with 2.5 million euros by the German Research Foundation (DFG). Early life and education Nikolaus Rajewsky is the son of the I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boris Rajewsky
Boris Rajewsky (russian: Борис Николаевич Раевский; ukr, Борис Миколайович Раєвський; 17 July 1893 – 22 November 1974) was a Russian Empire, Russian-born Germany, German biophysicist, who was one of the most influential researchers on the impact of radiation on living organisms in the 20th century. He served as Rector of the Goethe University Frankfurt from 1949 to 1951. Life and career He was the son of a Ukrainian people, Ukrainian noble family and grew up in the Russian Empire. He studied physics at the University of Kyiv, St. Vladimir Imperial University of Kiev from 1912, and obtained a doctorate there in 1918. He moved to Germany in 1922 and became a German citizen in 1927. He became the assistant of Friedrich Dessauer and obtained an additional doctorate at the Goethe University in 1929. In 1934 he became Professor of Physics at the Goethe University, and in 1943 he became Pro-Rector of the university. He served as the unive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Delbrück Center For Molecular Medicine
Max or MAX may refer to: Animals * Max (dog) (1983–2013), at one time purported to be the world's oldest living dog * Max (English Springer Spaniel), the first pet dog to win the PDSA Order of Merit (animal equivalent of OBE) * Max (gorilla) (1971–2004), a western lowland gorilla at the Johannesburg Zoo who was shot by a criminal in 1997 Brands and enterprises * Australian Max Beer * Max Hamburgers, a fast-food corporation * MAX Index, a Hungarian domestic government bond index * Max Fashion, an Indian clothing brand Computing * MAX (operating system), a Spanish-language Linux version * Max (software), a music programming language * Commodore MAX Machine * Multimedia Acceleration eXtensions, extensions for HP PA-RISC Films * ''Max'' (1994 film), a Canadian film by Charles Wilkinson * ''Max'' (2002 film), a film about Adolf Hitler * ''Max'' (2015 film), an American war drama film Games * '' Dancing Stage Max'', a 2005 game in the ''Dance Dance Revolution'' series * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MicroRNAs
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. miRNAs base-pair to complementary sequences in mRNA molecules, then gene silence said mRNA molecules by one or more of the following processes: (1) cleavage of mRNA strand into two pieces, (2) destabilization of mRNA by shortening its poly(A) tail, or (3) translation of mRNA into proteins. This last method of gene silencing is the least efficient of the three, and requires the aid of ribosomes. miRNAs resemble the small interfering RNAs (siRNAs) of the RNA interference (RNAi) pathway, except miRNAs derive from regions of RNA transcripts that fold back on themselves to form short hairpins, whereas siRNAs derive from longer regions of double-stranded RNA. The human genome may encode over 1900 miRNAs, although more recent analysis suggests th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNAi
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by other names, including ''co-suppression'', ''post-transcriptional gene silencing'' (PTGS), and ''quelling''. The detailed study of each of these seemingly different processes elucidated that the identity of these phenomena were all actually RNAi. Andrew Fire and Craig C. Mello shared the 2006 Nobel Prize in Physiology or Medicine for their work on RNAi in the nematode worm ''Caenorhabditis elegans'', which they published in 1998. Since the discovery of RNAi and its regulatory potentials, it has become evident that RNAi has immense potential in suppression of desired genes. RNAi is now known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Boston
Boston (), officially the City of Boston, is the state capital and most populous city of the Commonwealth of Massachusetts, as well as the cultural and financial center of the New England region of the United States. It is the 24th- most populous city in the country. The city boundaries encompass an area of about and a population of 675,647 as of 2020. It is the seat of Suffolk County (although the county government was disbanded on July 1, 1999). The city is the economic and cultural anchor of a substantially larger metropolitan area known as Greater Boston, a metropolitan statistical area (MSA) home to a census-estimated 4.8 million people in 2016 and ranking as the tenth-largest MSA in the country. A broader combined statistical area (CSA), generally corresponding to the commuting area and including Providence, Rhode Island, is home to approximately 8.2 million people, making it the sixth most populous in the United States. Boston is one of the oldest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peter Stadler
Peter may refer to: People * List of people named Peter, a list of people and fictional characters with the given name * Peter (given name) ** Saint Peter (died 60s), apostle of Jesus, leader of the early Christian Church * Peter (surname), a surname (including a list of people with the name) Culture * Peter (actor) (born 1952), stage name Shinnosuke Ikehata, Japanese dancer and actor * Peter (album), ''Peter'' (album), a 1993 EP by Canadian band Eric's Trip * Peter (1934 film), ''Peter'' (1934 film), a 1934 film directed by Henry Koster *Peter (2021 film), ''Peter'' (2021 film), Marathi language film * Peter (Fringe episode), "Peter" (''Fringe'' episode), an episode of the television series ''Fringe'' * Peter (novel), ''Peter'' (novel), a 1908 book by Francis Hopkinson Smith * Peter (short story), "Peter" (short story), an 1892 short story by Willa Cather Animals * Peter, the Lord's cat, cat at Lord's Cricket Ground in London * Peter (chief mouser), Chief Mouser between 1929 a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christiane Nüsslein-Volhard
Christiane (Janni) Nüsslein-Volhard (; born 20 October 1942) is a German developmental biologist and a 1995 Nobel Prize in Physiology or Medicine laureate. She is the only woman from Germany to have received a Nobel Prize in the sciences. Nüsslein-Volhard earned her PhD in 1974 from the University of Tübingen, where she studied protein-DNA interaction. She won the Albert Lasker Award for Basic Medical Research in 1991 and the Nobel Prize in Physiology or Medicine in 1995, together with Eric Wieschaus and Edward B. Lewis, for their research on the genetic control of embryonic development. Early life and education Nüsslein-Volhard was born in Magdeburg on 20 October 1942, the second of five children to Rolf Volhard, an architect, and Brigitte Haas Volhard, a nursery school teacher. She has four siblings: three sisters and one brother. She grew up and went to school in south Frankfurt, exposed to art and music and thus was "trained in looking at things and recognizing thing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
