Ketoacyl Synthase
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Ketoacyl Synthase
Ketoacyl synthases (KSs) catalyze the condensation reaction of acyl-CoA or acyl-acyl ACP with malonyl-CoA to form 3-ketoacyl-CoA or with malonyl-ACP to form 3-ketoacyl-ACP. This reaction is a key step in the fatty acid synthesis cycle, as the resulting acyl chain is two carbon atoms longer than before. KSs exist as individual enzymes, as they do in type II fatty acid synthesis and type II polyketide synthesis, or as domains in large multidomain enzymes, such as type I fatty acid synthases (FASs) and polyketide synthases (PKSs). KSs are divided into five families: KS1, KS2, KS3, KS4, and KS5. Multidomain enzyme systems Fatty acid synthase Fatty acid synthase (FAS) is the enzyme system involved in de novo fatty acid synthesis. FAS is an iterative multienzyme consisting of several component enzymes, one of which is ketoacyl synthase. There are two types of FASs: type I and type II. Type I FASs are highly integrated multidomain enzymes. They contain discrete functional domains resp ...
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Condensation Reaction
In organic chemistry, a condensation reaction is a type of chemical reaction in which two molecules are combined to form a single molecule, usually with the loss of a small molecule such as water. If water is lost, the reaction is also known as a dehydration synthesis. However other molecules can also be lost, such as ammonia, ethanol, acetic acid and hydrogen sulfide. The addition of the two molecules typically proceeds in a step-wise fashion to the addition product, usually in equilibrium, and with loss of a water molecule (hence the name condensation). The reaction may otherwise involve the functional groups of the molecule, and is a versatile class of reactions that can occur in acidic or basic conditions or in the presence of a catalyst. This class of reactions is a vital part of life as it is essential to the formation of peptide bonds between amino acids and to the biosynthesis of fatty acids. Many variations of condensation reactions exist. Common examples include the ...
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Brassica Napus
Rapeseed (''Brassica napus ''subsp.'' napus''), also known as rape, or oilseed rape, is a bright-yellow flowering member of the family Brassicaceae (mustard or cabbage family), cultivated mainly for its oil-rich seed, which naturally contains appreciable amounts of erucic acid. The term ''canola'' denotes a group of rapeseed cultivars which were bred to have very low levels of erucic acid and are especially prized for use as human and animal food. Rapeseed is the third-largest source of vegetable oil and the second-largest source of protein meal in the world. Description ''Brassica napus'' grows to in height with hairless, fleshy, pinnatifid and glaucous lower leaves which are stalked whereas the upper leaves have no Petiole (botany), petioles. ''Brassica napus'' can be distinguished from ''Brassica nigra'' by the upper leaves which do not clasp the stem, and from ''Brassica rapa'' by its smaller petals which are less than across. Rapeseed flowers are bright yellow and ...
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Beta-ketoacyl-ACP Synthase II
In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase II () is an enzyme that catalyzes the chemical reaction :(Z)-hexadec-11-enoyl- cyl-carrier-protein+ malonyl- cyl-carrier-protein\rightleftharpoons (Z)-3-oxooctadec-13-enoyl- cyl-carrier-protein+ CO2 + cyl-carrier-protein Thus, the two substrates of this enzyme are (Z)-hexadec-11-enoyl- cyl-carrier-proteinand malonyl- cyl-carrier-protein whereas its 3 products are (Z)-3-oxooctadec-13-enoyl- cyl-carrier-protein CO2, and acyl-carrier-protein. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is (Z)-hexadec-11-enoyl- cyl-carrier-proteinmalonyl- cyl-carrier-pr oteinC-acyltransferase (decarboxylating). Other names in common use include KASII, KAS II, FabF, 3-oxoacyl-acyl carrier protein synthase I, and beta-ketoacyl-ACP synthase II. This enzyme participates in fatty acid biosynthesis Fatty is a ...
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Beta-ketoacyl-acyl-carrier-protein Synthase II
In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase II () is an enzyme that catalyzes the chemical reaction :(Z)-hexadec-11-enoyl- cyl-carrier-protein+ malonyl- cyl-carrier-protein\rightleftharpoons (Z)-3-oxooctadec-13-enoyl- cyl-carrier-protein+ CO2 + cyl-carrier-protein Thus, the two substrates of this enzyme are (Z)-hexadec-11-enoyl- cyl-carrier-proteinand malonyl- cyl-carrier-protein whereas its 3 products are (Z)-3-oxooctadec-13-enoyl- cyl-carrier-protein CO2, and acyl-carrier-protein. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is (Z)-hexadec-11-enoyl- cyl-carrier-proteinmalonyl- cyl-carrier-pr oteinC-acyltransferase (decarboxylating). Other names in common use include KASII, KAS II, FabF, 3-oxoacyl-acyl carrier protein synthase I, and beta-ketoacyl-ACP synthase II. This enzyme participates in fatty acid biosynthesis Fatty is a ...
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Mycobacterium Tuberculosis
''Mycobacterium tuberculosis'' (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, ''M. tuberculosis'' has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, ''M. tuberculosis'' can appear weakly Gram-positive. Acid-fastness, Acid-fast stains such as Ziehl–Neelsen stain, Ziehl–Neelsen, or Fluorescence, fluorescent stains such as Auramine O, auramine are used instead to identify ''M. tuberculosis'' with a microscope. The physiology of ''M. tuberculosis'' is highly aerobic organism, aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the Mantoux test, tuberculin skin test, Acid-Fast Stain, acid-fast stain, Microbiological cultu ...
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Escherichia Coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escherichia'' that is commonly found in the lower intestine of warm-blooded organisms. Most ''E. coli'' strains are harmless, but some serotypes ( EPEC, ETEC etc.) can cause serious food poisoning in their hosts, and are occasionally responsible for food contamination incidents that prompt product recalls. Most strains do not cause disease in humans and are part of the normal microbiota of the gut; such strains are harmless or even beneficial to humans (although these strains tend to be less studied than the pathogenic ones). For example, some strains of ''E. coli'' benefit their hosts by producing vitamin K2 or by preventing the colonization of the intestine by pathogenic bacteria. These mutually beneficial relationships between ''E. col ...
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Streptococcus Pneumoniae
''Streptococcus pneumoniae'', or pneumococcus, is a Gram-positive, spherical bacteria, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), aerotolerant anaerobic member of the genus Streptococcus. They are usually found in pairs (diplococci) and do not form spores and are non motile. As a significant human pathogenic bacterium ''S. pneumoniae'' was recognized as a major cause of pneumonia in the late 19th century, and is the subject of many humoral immunity studies. ''Streptococcus pneumoniae'' resides asymptomatically in healthy carriers typically colonizing the respiratory tract, sinuses, and nasal cavity. However, in susceptible individuals with weaker immune systems, such as the elderly and young children, the bacterium may become pathogenic and spread to other locations to cause disease. It spreads by direct person-to-person contact via respiratory droplets and by auto inoculation in persons carrying the bacteria in their upper res ...
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Allium Ampeloprasu
''Allium'' is a genus of monocotyledonous flowering plants that includes hundreds of species, including the cultivated onion, garlic, scallion, shallot, leek, and chives. The generic name ''Allium'' is the Latin word for garlic,Gledhill, David (2008). "The Names of Plants". Cambridge University Press. (hardback), (paperback). pp 43 and the type species for the genus is ''Allium sativum'' which means "cultivated garlic".''Allium'' In: Index Nominum Genericorum. In: Regnum Vegetabile (see ''External links'' below). Carl Linnaeus first described the genus ''Allium'' in 1753. Some sources refer to Greek ἀλέω (aleo, to avoid) by reason of the smell of garlic. Various ''Allium'' have been cultivated from the earliest times, and about a dozen species are economically important as crops, or garden vegetables, and an increasing number of species are important as ornamental plants. The decision to include a species in the genus ''Allium'' is taxonomically difficult, and species b ...
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Spinacia Oleracea
Spinach (''Spinacia oleracea'') is a leafy green flowering plant native to central and western Asia. It is of the order Caryophyllales, family Amaranthaceae, subfamily Chenopodioideae. Its leaves are a common edible vegetable consumed either fresh, or after storage using preservation techniques by canning, freezing, or dehydration. It may be eaten cooked or raw, and the taste differs considerably; the high oxalate content may be reduced by steaming. It is an annual plant (rarely biennial), growing as tall as . Spinach may overwinter in temperate regions. The leaves are alternate, simple, ovate to triangular, and very variable in size: long and broad, with larger leaves at the base of the plant and small leaves higher on the flowering stem. The flowers are inconspicuous, yellow-green, in diameter, and mature into a small, hard, dry, lumpy fruit cluster across containing several seeds. In 2018, world production of spinach was 26.3 million tonnes, with China alone accounting f ...
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KS General Reaction
KS and variants may refer to: Businesses and organizations * , a German postwar commando frogman force * , a Norwegian type of company * Norwegian Association of Local and Regional Authorities * PenAir, Peninsula Airways, Anchorage, Alaska, US (IATA airline code) Language * Kashmiri language, a Dardic language of Kashmir (ISO 639 alpha-2 language code "ks") * Kernowek Standard, an orthography for Revived Cornish * Kiasu, Hokkien (a Chinese spoken variant) word for 'extreme fear of losing' (怕输) * Sound of the Latin letter X in many languages Places * Kansas (US postal abbreviation KS) * South Kalimantan, Indonesia (ISO 3166-2 province code) * Krems an der Donau, Austria (vehicle plate code) * Kassel, Germany (vehicle plate code) * Khatumo State, an unrecognised proto-state in northern Somalia * Northampton, Great Britain (vehicle plate code) * Košice-okolie District, Slovakia (vehicle plate code) Science, technology, and mathematics * Kaposi's sarcoma, a tumor caused by Hum ...
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Carthamus Tinctorius
Safflower (''Carthamus tinctorius'') is a highly branched, herbaceous, thistle-like annual plant in the family Asteraceae. It is commercially cultivated for vegetable oil extracted from the seeds and was used by the early Spanish colonies along the Rio Grande as a substitute for saffron. Plants are tall with globular flower heads having yellow, orange, or red flowers. Each branch will usually have from one to five flower heads containing 15 to 20 seeds per head. Safflower is native to arid environments having seasonal rain. It grows a deep taproot which enables it to thrive in such environments. Biology Plant morphology Safflower is a fast growing, erect, winter/spring-growing annual herb, that resembles a thistle. Originating from a leaf rosette emerges a branched central stem (also referred to as terminal stem), when day length and temperature increase. The main shoot reaches heights of . The plant also develops a strong taproot, growing as deep as . First lateral branch ...
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Beta-ketoacyl-ACP Synthase I
In enzymology, a beta-ketoacyl-acyl-carrier-protein synthase I () is an enzyme that catalyzes the chemical reaction :an acyl-acyl-carrier-protein + malonyl-acyl-carrier-protein \rightleftharpoons a 3-oxoacyl-acyl-carrier-protein + CO2 + acyl-carrier-protein Thus, the two substrates of this enzyme are acyl-acyl-carrier-protein and malonyl-acyl-carrier-protein, whereas its 3 products are 3-oxoacyl-acyl-carrier-protein, CO2, and acyl carrier protein. This enzyme participates in fatty acid biosynthesis. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. Nomenclature The systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature. A semisystematic name or semitrivial ... of this enzyme class is acyl- cyl-carrier-proteinmalonyl- c ...
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