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Kenneth B. Storey
Kenneth B. Storey (born October 23, 1949) is a Canadian scientist whose work draws from a variety of fields including biochemistry and molecular biology. He is a Professor of Biology, Biochemistry and Chemistry at Carleton University in Ottawa, Canada. Storey has a world-wide reputation for his research on biochemical adaptation - the molecular mechanisms that allow animals to adapt to and endure severe environmental stresses such as deep cold, oxygen deprivation, and desiccation. Biography Kenneth Storey studied biochemistry at the University of Calgary (B.Sc. '71) and zoology at the University of British Columbia (Ph.D. '74). Storey is a Professor of Biochemistry, cross-appointed in the Departments of Biology, Chemistry and Neuroscience and holds the Canada Research Chair in Molecular Physiology at Carleton University in Ottawa, Canada. Storey is an elected fellow of the Royal Society of Canada, of the Society for Cryobiology and of the American Association for the Advance ...
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Taber, Alberta
Taber is a town in southern Alberta, Canada that is surrounded by the Municipal District of Taber. It is approximately east of the City of Lethbridge at the intersection of Highway 3 and Highway 36. Taber is famous for its corn due to the large amounts of sunshine the area receives. It is therefore known as the ''Corn Capital of Canada'' and holds an annual " Cornfest" in the last week of August. History Originally, Taber was known as "Tank No. 77," and was used by the railway to fill up on water. In 1903, it is said that the first Mormon settlers from the U.S. were the ones to establish a hamlet at the Tank. After the town's post office was built in 1907, the CPR decided to call the town "Tabor," probably after Mount Tabor in the Holy Land. However, various letters and station heads came out printed "Taber," so the CPR changed the name to make it match the records. An alternate version of the town's name origin is that the first part of the word tabernacle was used by Mo ...
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Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent property, emergent properties, properties of cell (biology), cells, tissue (biology), tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell ...
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Rana Sylvatica
''Lithobates sylvaticus'' or ''Rana sylvatica'', commonly known as the wood frog, is a frog species that has a broad distribution over North America, extending from the boreal forest of the north to the southern Appalachians, with several notable disjunct populations including lowland eastern North Carolina. The wood frog has garnered attention from biologists because of its freeze tolerance, relatively great degree of terrestrialism (for a ranid), interesting habitat associations (peat bogs, vernal pools, uplands), and relatively long-range movements. The ecology and conservation of the wood frog has attracted research attention in recent years because they are often considered "obligate" breeders in ephemeral wetlands (sometimes called "vernal pools"), which are themselves more imperiled than the species that breed in them. The wood frog has been proposed to be the official state amphibian of New York. Description Wood frogs range from in length. Females are larger than ...
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Cryobiology
Cryobiology is the branch of biology that studies the effects of low temperatures on living things within Earth's cryosphere or in science. The word cryobiology is derived from the Greek words κρῧος ryos "cold", βίος ios "life", and λόγος ogos "word". In practice, cryobiology is the study of biological material or systems at temperatures below normal. Materials or systems studied may include proteins, cells, tissues, organs, or whole organisms. Temperatures may range from moderately hypothermic conditions to cryogenic temperatures. Areas of study At least six major areas of cryobiology can be identified: 1) study of cold-adaptation of microorganisms, plants ( cold hardiness), and animals, both invertebrates and vertebrates (including hibernation), 2) cryopreservation of cells, tissues, gametes, and embryos of animal and human origin for (medical) purposes of long-term storage by cooling to temperatures below the freezing point of water. This usually requires the ...
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Signal Transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway. When signaling pathways interact with one another they form networks, which allow cellular responses to be coordinated, often by combinatorial signaling events. At the molecular level, such responses include changes in the transcription or translation of genes, and post-translational and conformational changes in proteins, as well as changes in their location. These molecular events are the basic mechanisms controlling cell growth, ...
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Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression c ...
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Phosphorylation
In chemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion. This process and its inverse, dephosphorylation, are common in biology and could be driven by natural selection. Text was copied from this source, which is available under a Creative Commons Attribution 4.0 International License. Protein phosphorylation often activates (or deactivates) many enzymes. Glucose Phosphorylation of sugars is often the first stage in their catabolism. Phosphorylation allows cells to accumulate sugars because the phosphate group prevents the molecules from diffusing back across their transporter. Phosphorylation of glucose is a key reaction in sugar metabolism. The chemical equation for the conversion of D-glucose to D-glucose-6-phosphate in the first step of glycolysis is given by :D-glucose + ATP → D-glucose-6-phosphate + ADP : ΔG° = −16.7 kJ/mol (° indicates measurement at standard condition) Hepatic cells are freely permeable to glucose, and ...
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Gene Expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA (snRNA), the product is a functional non-coding RNA. Gene expression is summarized in the central dogma of molecular biology first formulated by Francis Crick in 1958, further developed in his 1970 article, and expanded by the subsequent discoveries of reverse transcription and RNA replication. The process of gene expression is used by all known life—eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses—to generate the macromolecular machinery for life. In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, '' ...
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Enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. Almost all metabolic processes in the cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts are catalytic RNA molecules, called ribozymes. Enzymes' specificity comes from their unique three-dimensional structures. Like all catalysts, enzymes increase the reaction ra ...
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Natural Sciences And Engineering Research Council
The Natural Sciences and Engineering Research Council of Canada (NSERC; french: Conseil de recherches en sciences naturelles et en génie du Canada, CRSNG) is the major federal agency responsible for funding natural sciences and engineering research in Canada. NSERC directly funds university professors and students as well as Canadian companies to perform research and training. With funding from the Government of Canada, NSERC supports the research of over 41,000 students, trainees and professors at universities and colleges in Canada with an annual budget of CA$1.1 billion in 2015. Its current director is Alejandro Adem. NSERC, combined with the Social Sciences and Humanities Research Council (SSHRC) and the Canadian Institutes of Health Research (CIHR), forms the major source of federal government funding to post-secondary research. These bodies are sometimes collectively referred to as the "Tri-Council" or "Tri-Agency". History NSERC came into existence on 1 May 1978 under th ...
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Ayerst Award
Ayerst is a surname. Notable people with the surname include: *Fiona Ayerst (born 1965), South African photographer *Peter Ayerst (1920–2014), Royal Air force officer * William Ayerst (1830–1904), British clergyman and missionary *William Ayerst Ingram William Ayerst Ingram or W. Ayerst Ingram RBA (27 April 1855 Twickenham, Surrey – 20 March 1913 Falmouth, Cornwall) was a painter and member of the Newlyn School. He did notable Landscape art and Marine art. In 1906 he joined the Royal In ...
(1855–1913), British painter {{surname ...
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Ottawa Life Sciences Council
Ottawa (, ; Canadian French: ) is the capital city of Canada. It is located at the confluence of the Ottawa River and the Rideau River in the southern portion of the province of Ontario. Ottawa borders Gatineau, Quebec, and forms the core of the Ottawa–Gatineau census metropolitan area (CMA) and the National Capital Region (NCR). Ottawa had a city population of 1,017,449 and a metropolitan population of 1,488,307, making it the fourth-largest city and fourth-largest metropolitan area in Canada. Ottawa is the political centre of Canada and headquarters to the federal government. The city houses numerous foreign embassies, key buildings, organizations, and institutions of Canada's government, including the Parliament of Canada, the Supreme Court, the residence of Canada's viceroy, and Office of the Prime Minister. Founded in 1826 as Bytown, and incorporated as Ottawa in 1855, its original boundaries were expanded through numerous annexations and were ultimately replac ...
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