Karel Frederik Wenckebach
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Karel Frederik Wenckebach
Karel Frederik Wenckebach (; March 24, 1864 – November 11, 1940) was a Dutch anatomist who was a native of the Hague. He studied medicine in Utrecht, and in 1901 become a professor of medicine at the University of Groningen. Later he was a professor at the Universities of Strasbourg (1911–14) and Vienna (1914–29). Contributions in cardiology Wenckebach is primarily remembered for his work in cardiology. In 1899 he provided a description of irregular pulses due to partial blockage of atrioventricular conduction, creating a progressive lengthening of conduction time in cardiac tissue. The condition was referred to as a "second degree AV block" and later named the "Wenckebach phenomenon" and reclassified as Mobitz type I block in Mobitz's 1924 paper. A similar phenomenon can also occur in the sinoatrial node where it gives rise to type I second degree SA block, and this is also known as a Wenckebach block; the two have distinct features on an ECG however. Wenckebach is ...
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The Hague
The Hague ( ; nl, Den Haag or ) is a city and municipality of the Netherlands, situated on the west coast facing the North Sea. The Hague is the country's administrative centre and its seat of government, and while the official capital of the Netherlands is Amsterdam, The Hague has been described as the country's de facto capital. The Hague is also the capital of the province of South Holland, and the city hosts both the International Court of Justice and the International Criminal Court. With a population of over half a million, it is the third-largest city in the Netherlands, after Amsterdam and Rotterdam. The Hague is the core municipality of the Greater The Hague urban area, which comprises the city itself and its suburban municipalities, containing over 800,000 people, making it the third-largest urban area in the Netherlands, again after the urban areas of Amsterdam and Rotterdam. The Rotterdam–The Hague metropolitan area, with a population of approximately 2.6&n ...
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Sinoatrial Block
A sinoatrial block (also spelled sinuatrial block) is a disorder in the normal rhythm of the heart, known as a heart block, that is initiated in the sinoatrial node. The initial action impulse in a heart is usually formed in the sinoatrial node (SA node) and carried through the atria, down the internodal atrial pathways to the atrioventricular node (AV) node. In normal conduction, the impulse would travel across the bundle of His (AV bundle), down the bundle branches, and into the Purkinje fibers. This would depolarize the ventricles and cause them to contract. In an SA block, the electrical impulse is delayed or blocked on the way to the atria, thus delaying the atrial beat. (An AV block, occurs in the AV node and delays ventricular depolarisation). SA blocks are categorized into three classes based on the length of the delay. Symptoms Sinoatrial blocks are typically well tolerated. They are not as serious as an AV block and most often do not require treatment. In some people, ...
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1864 Births
Events January–March * January 13 – American songwriter Stephen Foster ("Oh! Susanna", "Old Folks at Home") dies aged 37 in New York City, leaving a scrap of paper reading "Dear friends and gentle hearts". His parlor song " Beautiful Dreamer" is published in March. * January 16 – Denmark rejects an Austrian-Prussian ultimatum to repeal the Danish Constitution, which says that Schleswig-Holstein is part of Denmark. * January 21 – New Zealand Wars: The Tauranga campaign begins. * February – John Wisden publishes '' The Cricketer's Almanack for the year 1864'' in England; it will go on to become the major annual cricket reference publication. * February 1 – Danish-Prussian War (Second Schleswig War): 57,000 Austrian and Prussian troops cross the Eider River into Denmark. * February 15 – Heineken brewery founded in Netherlands. * February 17 – American Civil War: The tiny Confederate hand-propelled submarine ''H. L. Hunl ...
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Ireland
Ireland ( ; ga, Éire ; Ulster Scots dialect, Ulster-Scots: ) is an island in the Atlantic Ocean, North Atlantic Ocean, in Northwestern Europe, north-western Europe. It is separated from Great Britain to its east by the North Channel (Great Britain and Ireland), North Channel, the Irish Sea, and St George's Channel. Ireland is the List of islands of the British Isles, second-largest island of the British Isles, the List of European islands by area, third-largest in Europe, and the List of islands by area, twentieth-largest on Earth. Geopolitically, Ireland is divided between the Republic of Ireland (officially Names of the Irish state, named Ireland), which covers five-sixths of the island, and Northern Ireland, which is part of the United Kingdom. As of 2022, the Irish population analysis, population of the entire island is just over 7 million, with 5.1 million living in the Republic of Ireland and 1.9 million in Northern Ireland, ranking it the List of European islan ...
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Resuscitation (journal)
''Resuscitation'' is a monthly peer-reviewed medical journal covering research on cardiac arrest and cardiopulmonary resuscitation. It is an official journal of the European Resuscitation Council and is published by Elsevier. The editor-in-chief is Jerry Nolan (University of Southampton). Editorial introductions. ''Current Opinion in Critical Care'', 2013, Wolters Kluwer Health/Lippincott Williams & Wilkins The journal is abstracted and idexed in Current Contents, Index Medicus/MEDLINE/PubMed, Embase, Scopus, and the Science Citation Index Expanded. According to the ''Journal Citation Reports'', the journal has a 2018 impact factor of 4.572. See also * List of medical journals * European Resuscitation Council The European Resuscitation Council (ERC) is the European Interdisciplinary Council for Resuscitation Medicine and Emergency Medical Care Emergency medicine is the medical speciality concerned with the care of illnesses or injuries requiring i ... References Ext ...
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IJmuiden
IJ_(digraph).html" ;"title="n IJ (digraph)">n IJ (digraph) and that should remain the only places where they are used. > IJmuiden () is a port city in the Netherlands, Dutch province of North Holland. It is the main town in the municipality of Velsen which lies mainly to the south-east. Including its large sea locks, it straddles the mouth of the North Sea Canal to Amsterdam. To the south it abuts a large reserve of plant-covered dunes, the Zuid-Kennemerland National Park. The city is on the south bank; the north bank is otherwise a steel plant and Velsen-Noord. It is north northwest of Haarlem which is due west of Amsterdam. The port is a deepwater port suited to fully laden Panamax ships, and fourth port of the Netherlands. The internal capitalization within IJmuiden is as IJ is a digraph in modern Dutch so in some typefaces recognised as a ligature which places it in one typed or handwritten space. History In the Roman era, the district was already inhabited, a ...
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Amsterdam
Amsterdam ( , , , lit. ''The Dam on the River Amstel'') is the Capital of the Netherlands, capital and Municipalities of the Netherlands, most populous city of the Netherlands, with The Hague being the seat of government. It has a population of 907,976 within the city proper, 1,558,755 in the City Region of Amsterdam, urban area and 2,480,394 in the Amsterdam metropolitan area, metropolitan area. Located in the Provinces of the Netherlands, Dutch province of North Holland, Amsterdam is colloquially referred to as the "Venice of the North", for its large number of canals, now designated a World Heritage Site, UNESCO World Heritage Site. Amsterdam was founded at the mouth of the Amstel River that was dammed to control flooding; the city's name derives from the Amstel dam. Originally a small fishing village in the late 12th century, Amsterdam became a major world port during the Dutch Golden Age of the 17th century, when the Netherlands was an economic powerhouse. Amsterdam is th ...
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Haarlem
Haarlem (; predecessor of ''Harlem'' in English) is a city and municipality in the Netherlands. It is the capital of the province of North Holland. Haarlem is situated at the northern edge of the Randstad, one of the most populated metropolitan areas in Europe; it is also part of the Amsterdam metropolitan area, being located about 15 km to the west of the core city of Amsterdam. Haarlem had a population of in . Haarlem was granted city status or '' stadsrechten'' in 1245, although the first city walls were not built until 1270. The modern city encompasses the former municipality of Schoten as well as parts that previously belonged to Bloemendaal and Heemstede. Apart from the city, the municipality of Haarlem also includes the western part of the village of Spaarndam. Newer sections of Spaarndam lie within the neighbouring municipality of Haarlemmermeer. Geography Haarlem is located on the river Spaarne, giving it its nickname 'Spaarnestad' (Spaarne city). It is situated a ...
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Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water to impart a bitter taste. Common side effects include headache, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound. How it works as a medicin ...
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Left Atrium
The atrium ( la, ātrium, , entry hall) is one of two upper chambers in the heart that receives blood from the circulatory system. The blood in the atria is pumped into the heart ventricles through the atrioventricular valves. There are two atria in the human heart – the left atrium receives blood from the pulmonary circulation, and the right atrium receives blood from the venae cavae of the systemic circulation. During the cardiac cycle the atria receive blood while relaxed in diastole, then contract in systole to move blood to the ventricles. Each atrium is roughly cube-shaped except for an ear-shaped projection called an atrial appendage, sometimes known as an auricle. All animals with a closed circulatory system have at least one atrium. The atrium was formerly called the 'auricle'. That term is still used to describe this chamber in some other animals, such as the ''Mollusca''. They have thicker muscular walls than the atria do. Structure Humans have a four-chambered ...
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Bachmann's Bundle
In the heart's conduction system, Bachmann's bundle (also called the Bachmann bundle or the interatrial band) is a branch of the anterior internodal tract that resides on the inner wall of the left atrium. It is a broad band of cardiac muscle that passes from the right atrium, between the superior vena cava and the ascending aorta. Bachmann's bundle is, during normal sinus rhythm, the preferential path for electrical activation of the left atrium. It is therefore considered to be part of the "atrial conduction system" of the heart. History In 1916, Jean George Bachmann conducted canine experiments. He found that clamping the muscular bundle of fibers that connects the atria caused a significant conduction delay. Structure Bachman's bundle receives its blood supply from the sinoatrial nodal artery (right, left or both). Besides Bachmann's bundle, the other three conduction tracts that constitute the ''atrial conduction system'' are known as the anterior, middle, and posterior ...
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