Kappapapillomavirus
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Kappapapillomavirus
''Kappapapillomavirus'' is a genus of viruses, in the family ''Papillomaviridae ''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected ...''. Rabbits serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: cutaneous and mucosal lesions. Taxonomy The following two species are assigned to the genus: * '' Kappapapillomavirus 1'' * '' Kappapapillomavirus 2'' Structure Viruses in ''Kappapapillomavirus'' are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins, and has 6, 8 open reading frames. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host recept ...
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Kappapapillomavirus 1
''Kappapapillomavirus'' is a genus of viruses, in the family ''Papillomaviridae ''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected ...''. Rabbits serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: cutaneous and mucosal lesions. Taxonomy The following two species are assigned to the genus: * '' Kappapapillomavirus 1'' * '' Kappapapillomavirus 2'' Structure Viruses in ''Kappapapillomavirus'' are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins, and has 6, 8 open reading frames. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host recept ...
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Kappapapillomavirus 2
The Shope papilloma virus (SPV), also known as cottontail rabbit papilloma virus (CRPV) or ''Kappapapillomavirus 2'', is a papillomavirus which infects certain leporids, causing keratinous carcinomas resembling horns, typically on or near the animal's head. The carcinomas can metastasize or become large enough to interfere with the host's ability to eat, causing starvation. Richard E. Shope investigated the horns and discovered the virus in 1933, an important breakthrough in the study of oncoviruses. The virus was originally discovered in cottontail rabbits in the Midwestern U.S., but can also infect brush rabbits, black-tailed jackrabbits, snowshoe hares, and European rabbits. History In the 1930s, hunters in northwestern Iowa reported that the rabbits they shot had several "horn" protrusions on many parts of their bodies including their faces and necks. The virus is also a possible source of myths about the jackalope, a rabbit with the horns of an antelope, and related cry ...
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Papillomaviridae
''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected mammals, but also other vertebrates such as birds, snakes, turtles and fish. Infection by most papillomavirus types, depending on the type, is either asymptomatic (e.g. most Beta-PVs) or causes small benign tumors, known as papillomas or warts (e.g. human papillomavirus 1, HPV6 or HPV11). Papillomas caused by some types, however, such as human papillomaviruses 16 and 18, carry a risk of becoming cancerous. Papillomaviruses are usually considered as highly host- and tissue-tropic, and are thought to rarely be transmitted between species. Papillomaviruses replicate exclusively in the basal layer of the body surface tissues. All known papillomavirus types infect a particular body surface, typically the skin or mucosal epithelium of the gen ...
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Papillomavirus
''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, traditionally referred to as "types", have been identified infecting all carefully inspected mammals, but also other vertebrates such as birds, snakes, turtles and fish. Infection by most papillomavirus types, depending on the type, is either asymptomatic (e.g. most Beta-PVs) or causes small benign tumors, known as papillomas or warts (e.g. human papillomavirus 1, HPV6 or HPV11). Papillomas caused by some types, however, such as human papillomaviruses 16 and 18, carry a risk of becoming cancerous. Papillomaviruses are usually considered as highly host- and tissue-tropic, and are thought to rarely be transmitted between species. Papillomaviruses replicate exclusively in the basal layer of the body surface tissues. All known papillomavirus types infect a particular body surface, typically the skin or mucosal epithelium of the gen ...
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Viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i.e ...
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