''Kappapapillomavirus'' is a genus of
viruses, in the family ''
Papillomaviridae''.
Rabbits serve as natural hosts. There are two species in this genus. Diseases associated with this genus include: cutaneous and mucosal lesions.
Taxonomy
The following two species are assigned to the genus:
* ''
Kappapapillomavirus 1
''Kappapapillomavirus'' is a genus of viruses, in the family ''Papillomaviridae
''Papillomaviridae'' is a family of non- enveloped DNA viruses whose members are known as papillomaviruses. Several hundred species of papillomaviruses, tradition ...
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* ''
Kappapapillomavirus 2
The Shope papilloma virus (SPV), also known as cottontail rabbit papilloma virus (CRPV) or ''Kappapapillomavirus 2'', is a papillomavirus which infects certain leporids, causing keratinous carcinomas resembling horns, typically on or near the an ...
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Structure
Viruses in ''Kappapapillomavirus'' are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length. The genome codes for 6 proteins, and has 6, 8 open reading frames.
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown.
Rabbits serve as the natural host. Transmission routes are contact.
References
External links
ICTV Report ''Papillomaviridae''
{{Taxonbar, from=Q18819943
Papillomavirus
Virus genera