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Kang Zhang
Kang Zhang () is a Chinese-American ophthalmologist specializing in ophthalmic genetics and aging processes in the eye. He is currently a Professor of the Faculty of Medicine at Macau University of Science and Technology. He was previously a Professor of Ophthalmology and the Founding Director of the Institute for Genomic Medicine at the University of California, San Diego. Zhang is particularly known for his work on lanosterol, stem cell research (particularly limbal stem cells), gene editing, and artificial intelligence. Education Born in Chengdu, Sichuan Province, China, Zhang obtained his B.S. in Biochemistry from Sichuan University in Chengdu, China in 1984. In 1991, Zhang graduated with a Ph.D. in Genetics from Harvard University. Subsequently, Zhang obtained his M.D. from a Harvard University Medical School and Massachusetts Institute of Technology Joint M.D. Program with '' magna cum laude'' honors in 1995. Career After completing an ophthalmology residency at the Wi ...
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Zhang (surname)
Zhang () is the third most common surname in China and Taiwan (commonly spelled as "Chang" in Taiwan), and it is one of the most common surnames in the world. Zhang is the pinyin romanization of the very common Chinese surname written in simplified characters and in traditional characters. It is spoken in the first tone: ''Zhāng''. It is a surname that exists in many languages and cultures, corresponding to the surname 'Archer' in English for example. In the Wade-Giles system of romanization, it is romanized as "Chang", which is commonly used in Taiwan; "Cheung" is commonly used in Hong Kong as romanization. It is also the pinyin romanization of the less-common surnames (''Zhāng''), which is the 40th name on the ''Hundred Family Surnames'' poem. There is the even-less common (''Zhǎng''). was listed 24th in the famous Song-era ''Hundred Family Surnames'', contained in the verse 何呂施張 (He Lü Shi Zhang). Today, it is one of the most common surnames in the world a ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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American Institute For Medical And Biological Engineering
The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization founded in 1991, and headquartered in Washington. It represents 50,000 medical and biomedical engineers, and academic institutions, private industry, and professional engineering societies. College of Fellows Since AIMBE’s inception, over 2,000 individuals have been inducted to AIMBE’s College of Fellows. These fellows include heads of medical and engineering schools. Some Fellows work for the government, acting as consultants, or directing clinical trials. Some Fellows are members of other prominent academic institutions, such as the National Academy of Engineering, Institute of Medicine and the National Academy of Sciences. Others have received the National Medal of Science and the National Medal of Technology. Fellows use the post-nominal FAIMBE. Industry Council The Industry Council consists of corporate leaders in the biomedical engineering field. Partnership with FDA AIM ...
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Cataract
A cataract is a cloudy area in the lens of the eye that leads to a decrease in vision. Cataracts often develop slowly and can affect one or both eyes. Symptoms may include faded colors, blurry or double vision, halos around light, trouble with bright lights, and trouble seeing at night. This may result in trouble driving, reading, or recognizing faces. Poor vision caused by cataracts may also result in an increased risk of falling and depression. Cataracts cause 51% of all cases of blindness and 33% of visual impairment worldwide. Cataracts are most commonly due to aging but may also occur due to trauma or radiation exposure, be present from birth, or occur following eye surgery for other problems. Risk factors include diabetes, longstanding use of corticosteroid medication, smoking tobacco, prolonged exposure to sunlight, and alcohol. The underlying mechanism involves accumulation of clumps of protein or yellow-brown pigment in the lens that reduces transmission of li ...
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Eyedrop
Eye drops or eyedrops are liquid drops applied directly to the surface of the eye usually in small amounts such as a single drop or a few drops. Eye drops usually contain saline to match the salinity of the eye. Drops containing only saline and sometimes a lubricant are often used as artificial tears to treat dry eyes or simple eye irritation such as itching or redness. Eye drops may also contain one or more medications to treat a wide variety of eye diseases. Depending on the condition being treated, they may contain steroids, antihistamines, sympathomimetics, beta receptor blockers, parasympathomimetics, parasympatholytics, prostaglandins, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, antifungals, or topical anesthetics. Eye drops have less of a risk of side effects than do oral medicines, and such risk can be minimized by occluding the lacrimal punctum (i.e. pressing on the inner corner of the eye) for a short while after instilling drops. Prior to the ...
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Epigenetic Marker
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression can ...
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Molecular Clock
The molecular clock is a figurative term for a technique that uses the mutation rate of biomolecules to deduce the time in prehistory when two or more life forms diverged. The biomolecular data used for such calculations are usually nucleotide sequences for DNA, RNA, or amino acid sequences for proteins. The benchmarks for determining the mutation rate are often fossil or archaeological dates. The molecular clock was first tested in 1962 on the hemoglobin protein variants of various animals, and is commonly used in molecular evolution to estimate times of speciation or radiation. It is sometimes called a gene clock or an evolutionary clock. Early discovery and genetic equidistance The notion of the existence of a so-called "molecular clock" was first attributed to Émile Zuckerkandl and Linus Pauling who, in 1962, noticed that the number of amino acid differences in hemoglobin between different lineages changes roughly linearly with time, as estimated from fossil evidence. ...
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Trey Ideker
Trey Ideker is a professor of medicine and bioengineering at UC San Diego. He is the Director of the National Resource for Network Biology, the San Diego Center for Systems Biology, and the Cancer Cell Map Initiative. He uses genome-scale measurements to construct network models of cellular processes and disease. Education Ideker received Bachelor’s and Master’s degrees from M.I.T. in Electrical Engineering and Computer Science, and his Ph.D. from the University of Washington in Molecular Biology under the supervision of Leroy Hood. While working with Hood, Ideker was one of the first researchers to publish an integrated computational model of a metabolic network. As of 2017, the paper describing this model has been cited over 2,200 times. Career Following his PhD, Ideker worked at the Whitehead Institute for Biomedical Research at M.I.T. In 2003, Ideker joined UC San Diego as an Assistant Professor of Bioengineering. In 2006, became an Associate Professor of Bioengineering a ...
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University Of Utah
The University of Utah (U of U, UofU, or simply The U) is a public research university in Salt Lake City, Utah. It is the flagship institution of the Utah System of Higher Education. The university was established in 1850 as the University of Deseret () by the General Assembly of the provisional State of Deseret, making it Utah's oldest institution of higher education. It received its current name in 1892, four years before Utah attained statehood, and moved to its current location in 1900. As of Fall 2019, there were 24,485 undergraduate students and 8,333 graduate students, for an enrollment total of 32,818, making it the second largest public university in the state after Utah Valley University. Graduate studies include the S.J. Quinney College of Law and the School of Medicine, Utah's first medical school. It is a member of the Association of American Universities (AAU) and is classified among "R1: Doctoral Universities – Very high research activity". According to the ...
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Cleveland Clinic Foundation
Cleveland Clinic is a nonprofit American academic medical center based in Cleveland, Ohio. Owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation established in 1921, it runs a 170-acre (69 ha) campus in Cleveland, as well as 11 affiliated hospitals, 19 family health centers in Northeast Ohio, and hospitals in Florida and Nevada. International operations include the Cleveland Clinic Abu Dhabi hospital in the United Arab Emirates and Cleveland Clinic Canada, which has two executive health and sports medicine clinics in Toronto."Facts & Figures"
Cleveland Clinic.
Another hospital campus in the United Kingdom, Cleveland Clinic London, opened to outpatients in 2021 and is scheduled to fully open in 2022. Tomislav Mihaljevic is the president and CEO. Cleveland ...
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Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest Philanthropy, philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as :Presidents of Johns Hopkins University, Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all Higher education in the U ...
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Magna Cum Laude
Latin honors are a system of Latin phrases used in some colleges and universities to indicate the level of distinction with which an academic degree has been earned. The system is primarily used in the United States. It is also used in some Southeastern Asian countries with European colonial history, such as Indonesia and the Philippines, although sometimes translations of these phrases are used instead of the Latin originals. The honors distinction should not be confused with the honors degrees offered in some countries, or with honorary degrees. The system usually has three levels of honor: ''cum laude'', ''magna cum laude'', and ''summa cum laude''. Generally, a college or university's regulations set out definite criteria a student must meet to obtain a given honor. For example, the student might be required to achieve a specific grade point average, submit an honors thesis for evaluation, be part of an honors program, or graduate early. Each school sets its own standards. ...
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