Kurt Henseleit
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Kurt Henseleit
Kurt Henseleit (1907–1973) studied medicine in Berlin, where he was born, with final exams 1929 and was beginning in the winter semester 1930/31 a graduate student of and assistant to Hans Krebs in Freiburg im Breisgau, where he got his M.D. Between them they discovered the urea cycle (known also as the ''Krebs-Henseleit cycle''), and developed the Krebs-Henseleit solution. Later in life he was a physician (Facharzt) in Friedrichshafen Friedrichshafen ( or ; Low Alemannic: ''Hafe'' or ''Fridrichshafe'') is a city on the northern shoreline of Lake Constance (the ''Bodensee'') in Southern Germany, near the borders of both Switzerland and Austria. It is the district capital (''Kre .... References 1907 births 1973 deaths 20th-century German physicians {{biochemist-stub ...
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Urea Cycle
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic. The urea cycle converts highly toxic ammonia to urea for excretion. This cycle was the first metabolic cycle to be discovered ( Hans Krebs and Kurt Henseleit, 1932), five years before the discovery of the TCA cycle. This cycle was described in more detail later on by Ratner and Cohen. The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Function Amino acid catabolism results in waste ammonia. All animals need a way to excrete this product. Most aquatic organisms, or ammonotelic organisms, excrete ammonia without converting it. Organisms that cannot easily and safely remove nitrogen as ammonia convert it to a less toxic substance, such as urea, via the urea cycle, which occurs mainly in the liver. Urea produced by the liver is th ...
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Krebs–Henseleit Solution
Krebs–Henseleit solution, developed by Hans Krebs and Kurt Henseleit, is a solution containing sodium (Na), potassium (K), chloride (Cl), calcium (Ca), magnesium sulfate (MgSO4), bicarbonate (HCO3), phosphate (PO4), glucose, and sometimes supplemented with albumin, and tromethamine (THAM). It has been used experimentally, for instance to study arteries ''ex vivo'', in Langendorff heart preparations, and during isolated muscle testing of mammalian skeletal muscles Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscle .... References Solutions {{pharma-stub ...
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Hans Adolf Krebs
Sir Hans Adolf Krebs, FRS (, ; 25 August 1900 – 22 November 1981) was a German-born British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of humans and many other organisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the key sequence of metabolic reactions that provides energy in the cells of humans and other oxygen-respiring organisms; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, which is a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi. Krebs died in 1981 in Oxford, wh ...
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Urea Cycle
The urea cycle (also known as the ornithine cycle) is a cycle of biochemical reactions that produces urea (NH2)2CO from ammonia (NH3). Animals that use this cycle, mainly amphibians and mammals, are called ureotelic. The urea cycle converts highly toxic ammonia to urea for excretion. This cycle was the first metabolic cycle to be discovered ( Hans Krebs and Kurt Henseleit, 1932), five years before the discovery of the TCA cycle. This cycle was described in more detail later on by Ratner and Cohen. The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Function Amino acid catabolism results in waste ammonia. All animals need a way to excrete this product. Most aquatic organisms, or ammonotelic organisms, excrete ammonia without converting it. Organisms that cannot easily and safely remove nitrogen as ammonia convert it to a less toxic substance, such as urea, via the urea cycle, which occurs mainly in the liver. Urea produced by the liver is th ...
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Friedrichshafen
Friedrichshafen ( or ; Low Alemannic: ''Hafe'' or ''Fridrichshafe'') is a city on the northern shoreline of Lake Constance (the ''Bodensee'') in Southern Germany, near the borders of both Switzerland and Austria. It is the district capital (''Kreisstadt'') of the Bodensee district in the federal state of Baden-Württemberg. Friedrichshafen has a population of about 58,000. History 19th and early 20th century Friedrichshafen was established in 1811 as part of the new Kingdom of Württemberg, an ally of France during the Napoleonic Wars. It was named for King Frederick I of Württemberg, who privileged it as a free port and transshipment point for the kingdom's Swiss trade. Friedrichshafen was created from the former city of Buchhorn, whose coat of arms it adopted. The new city also incorporated the former village of Hofen, whose monastery was refurbished to serve as the summer residence of the Württemberger kings. King William I continued improving the city, including the purch ...
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1907 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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1973 Deaths
Events January * January 1 - The United Kingdom, the Republic of Ireland and Denmark enter the European Economic Community, which later becomes the European Union. * January 15 – Vietnam War: Citing progress in peace negotiations, U.S. President Richard Nixon announces the suspension of offensive action in North Vietnam. * January 17 – Ferdinand Marcos becomes President for Life of the Philippines. * January 20 – Richard Nixon is sworn in for a second term as President of the United States. Nixon is the only person to have been sworn in twice as President ( 1969, 1973) and Vice President of the United States ( 1953, 1957). * January 22 ** George Foreman defeats Joe Frazier to win the heavyweight world boxing championship. ** A Royal Jordanian Boeing 707 flight from Jeddah crashes in Kano, Nigeria; 176 people are killed. * January 27 – U.S. involvement in the Vietnam War ends with the signing of the Paris Peace Accords. February * February 8 – A militar ...
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