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Knome
Knome, Inc. was a human genome interpretation company based in Cambridge, Massachusetts. Launched in 2007, Knome focused on improving quality of life by applying scientific insights gained from the Whole genome sequencing, interpretation of human genomes. Their products and services helped identify and classify the variants, genes, and gene sets that are likely to govern or underlie a specific disease, tumor, or drug response. Their clients included academic, pharmaceutical and medical researchers. In 2015, it was acquired by Tute Genomics. Technology Knome developed proprietary technologies that automated many of the manual tasks involved in interpreting human whole genomes. These technologies were designed to address the informatics and workflow bottlenecks that typically hinder whole genome interpretation. The company’s core technology, kGAP, was developed in 2009 and served as the foundation for a number of Knome’s products and services including the knoSYS® platform. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tute Genomics
Tute Genomics is a genomics startup that provides a cloud-based web application for rapid and accurate annotation of human genomic data. Built on the expertise of ANNOVAR, Tute assists researchers in identifying disease genes and biomarkers, and assists clinicians/labs in performing genetic diagnosis. Based in Provo, Utah, Tute was co-founded by Dr. Kai Wang, an Assistant Professor at the University of Southern California (USC); and Reid Robison, Dr. Reid J. Robison, a board-certified psychiatrist with fellowship training in both neurodevelopmental genetics and bioinformatics. The word "tute" means "personal" in the Na’vi language created for the 2009 film Avatar (2009 film), ''Avatar'' by Paul Frommer, a linguist and communications professor at the USC Marshall School of Business. Tute Genomics was acquired by PierianDX in 2016. Timeline 2013 * Tute Genomics launched in 2013 and entered the accelerator, BoomStartup. By "demo day" of BoomStartup, Tute had raised their seed round ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ozzy Osbourne
John Michael "Ozzy" Osbourne (born 3 December 1948) is an English singer, songwriter, and television personality. He rose to prominence during the 1970s as the lead vocalist of the heavy metal band Black Sabbath, during which period he adopted the nickname "Prince of Darkness". Born and raised in Birmingham, Osbourne became a founding member of Black Sabbath in 1967, and sang on every album from their debut in 1970 to ''Never Say Die!'' in 1978. The band was highly influential on the development of heavy metal music, in particular their critically acclaimed releases ''Paranoid'', ''Master of Reality'' and ''Sabbath Bloody Sabbath''. Osbourne was fired from Black Sabbath in 1979 due to alcohol and drug problems, but went on to have a successful solo career, releasing 13 studio albums, the first seven of which received multi-platinum certifications in the US. Osbourne has since reunited with Black Sabbath on several occasions. He rejoined in 1997 and helped record the group ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henry Louis Gates Jr
Henry Louis "Skip" Gates Jr. (born September 16, 1950) is an American literary critic, professor, historian, and filmmaker, who serves as the Alphonse Fletcher University Professor and Director of the Hutchins Center for African and African American Research at Harvard University. He is a Trustee of the Gilder Lehrman Institute of American History. He rediscovered the earliest African-American novels, long forgotten, and has published extensively on appreciating African-American literature as part of the Western canon. In addition to producing and hosting previous series on the history and genealogy of prominent American figures, since 2012, Gates has been host of the television series '' Finding Your Roots'' on PBS. It combines the work of expert researchers in genealogy, history, and genetics historic research to tell guests about their ancestors' lives and histories. Early life and education Gates was born in Keyser, West Virginia, to Henry Louis Gates Sr. (c. 1913–2010) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whole Genome Sequencing
Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondrial DNA, mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of DNA sequencing, gene sequencing at Single-nucleotide polymorphism, SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Faces Of America
''Faces of America'' is a four-part Public Broadcasting Service (PBS) Public television television series hosted by Professor Henry Louis Gates. The series originally aired February 10 – March 3, 2010 from 8–9 p.m. ET.PBS WNET: About Faces of America Accessed online 7 March 2010. In , this program aired on each Sunday at 7:30pm from 9 -30 January 2011. About It uses genealogical research and genetics to find the family history of 12 Americans:[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Privately Held Company
A privately held company (or simply a private company) is a company whose shares and related rights or obligations are not offered for public subscription or publicly negotiated in the respective listed markets, but rather the company's stock is offered, owned, traded, exchanged privately, or Over-the-counter (finance), over-the-counter. In the case of a closed corporation, there are a relatively small number of shareholders or company members. Related terms are closely-held corporation, unquoted company, and unlisted company. Though less visible than their public company, publicly traded counterparts, private companies have major importance in the world's economy. In 2008, the 441 list of largest private non-governmental companies by revenue, largest private companies in the United States accounted for ($1.8 trillion) in revenues and employed 6.2 million people, according to ''Forbes''. In 2005, using a substantially smaller pool size (22.7%) for comparison, the 339 companies on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms become more common. The most obvious early symptoms are tremor, rigidity, slowness of movement, and difficulty with walking. Cognitive and behavioral problems may also occur with depression, anxiety, and apathy occurring in many people with PD. Parkinson's disease dementia becomes common in the advanced stages of the disease. Those with Parkinson's can also have problems with their sleep and sensory systems. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain, leading to a dopamine deficit. The cause of this cell death is poorly understood, but involves the build-up of misfolded proteins into Lewy bodies in the neurons. Collectively, the main motor symptoms are also known as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sharon Osbourne
Sharon Rachel Osbourne (née Levy, later Arden; born 9 October 1952) is a British-American television personality, music manager and author. She is married to heavy metal singer-songwriter Ozzy Osbourne and came to prominence while appearing on ''The Osbournes'' (2002–2005), a reality television show that aired on MTV, which followed her family's daily life. Osbourne later became a talent show judge on television shows, such as ''The X Factor'' (2004–2007, 2013, 2016–2017) and '' America's Got Talent'' (2007–2012). Osbourne is credited with reviving her husband's heavy metal career by founding the summer Ozzfest tour, which was held almost annually between 1996 and 2018. From 2003 to 2006, she hosted her own television talk show ''The Sharon Osbourne Show.'' In 2010, Osbourne was a contestant on NBC's ''The Celebrity Apprentice'', and became a co-host on the CBS talk show '' The Talk,'' appearing until her termination in 2021. In 2022, she joined TalkTV, hosting a pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nova (American TV Series)
''Nova'' (stylized as ''NOVΛ'') is an American popular science television program produced by WGBH in Boston, Massachusetts, since 1974. It is broadcast on PBS in the United States, and in more than 100 other countries. The program has won many major television awards. ''Nova'' often includes interviews with scientists doing research in the subject areas covered and occasionally includes footage of a particular discovery. Some episodes have focused on the history of science. Examples of topics covered include the following: Colditz Castle, the Drake equation, elementary particles, the 1980 eruption of Mount St. Helens, Fermat's Last Theorem, the AIDS epidemic, global warming, moissanite, Project Jennifer, storm chasing, Unterseeboot 869, Vinland, Tarim mummies, and the COVID-19 pandemic. The ''Nova'' programs have been praised for their pacing, writing, and editing. Websites that accompany the segments have also won awards. Episodes History ''Nova'' was first aired o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins School Of Medicine
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889. It has consistently ranked among the top medical schools in the United States in terms of the number/amount of research grants/funding awarded by the National Institutes of Health, among other measures. History The founding physicians (the "Four Doctors") of the Johns Hopkins School of Medicine included pathologist William Henry Welch (1850–1934), the first dean of the school and a mentor to generations of research scientists; a Canadian, internist Sir William Osler (1849–1919), regarded as the ''Father of Modern Medicine'', having been perhaps the most influential physician of the late 19th and early 20th centuries as author of '' The Principles and Practice of Medicine'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cloud Computing
Cloud computing is the on-demand availability of computer system resources, especially data storage ( cloud storage) and computing power, without direct active management by the user. Large clouds often have functions distributed over multiple locations, each of which is a data center. Cloud computing relies on sharing of resources to achieve coherence and typically uses a "pay as you go" model, which can help in reducing capital expenses but may also lead to unexpected operating expenses for users. Value proposition Advocates of public and hybrid clouds claim that cloud computing allows companies to avoid or minimize up-front IT infrastructure costs. Proponents also claim that cloud computing allows enterprises to get their applications up and running faster, with improved manageability and less maintenance, and that it enables IT teams to more rapidly adjust resources to meet fluctuating and unpredictable demand, providing burst computing capability: high computing p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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